Auhtors: Santos HO, de Moraes WM, da Silva GA, restes J, Schoenfeld BJ PMID: 31221273 DOI: 10.1016/j.clnesp.2019.05.008 Abstract Vinegar intake is considered a food item that improves blood glucose in humans. This review aimed to discuss studies that investigated the impact of vinegar intake on the glycemic profile in humans and the putative mechanistic cellular [...]

Auhtors: Mukherjee P, Augur ZM, Li M, Hill C, Greenwood B, Domin MA, et al. Abstract Glioblastoma (GBM) is an aggressive primary human brain tumour that has resisted effective therapy for decades. Although glucose and glutamine are the major fuels that drive GBM growth and invasion, few studies have targeted these fuels for therapeutic management. [...]

Authors: Wang Y, Lin H, Lin BW, Lin JD PMID: 31111241 PMCID: PMC6527630 DOI: 10.1186/s13613-019-0532-9 Abstract Background: Low levels of ascorbic acid (AA) have been detected in critically ill patients in which AA supplementation leads to promising outcomes. However, the ability of AA to reduce mortality in critically ill patients remains controversial. In this study, [...]

Auhtors: Huang W, Sundquist J, Sundquist K, Ji J PMID: 31103628 DOI: 10.1053/j.gastro.2019.05.012 Abstract Background & aims: Phosphodiesterase 5 (PDE5) inhibitors have been proposed to have chemopreventative effects on colorectal cancer (CRC), although data are needed from population-based studies. We performed a nationwide cohort study to investigate the association between the use of PDE5 inhibitors [...]

Auhtors: Gorodetska I, Kozeretska I, Dubrovska A PMID: 31205572 PMCID: PMC6548160 DOI: 10.7150/jca.30410 Abstract Carcinogenesis is a multistep process, and tumors frequently harbor multiple mutations regulating genome integrity, cell division and death. The integrity of cellular genome is closely controlled by the mechanisms of DNA damage signaling and DNA repair. The association of breast cancer [...]

Riva A, Ronchi M, Petrangolini G, Bosisio S, Allegrini P. PMID: 30328058 PMCID: PMC6418071 DOI: 10.1007/s13318-018-0517-3 Abstract Background and objectives: The importance of quercetin and flavonoids in the diet and as food supplements is well known, and literature studies support their potential use to treat several human diseases. Many beneficial properties have been described [...]

Authors: Theoharides TC, Tsilioni I, Ren H PMID: 30884251 PMCID: PMC7003574 DOI: 10.1080/1744666X.2019.1596800 Abstract An increasing number of patients present with multiple symptoms affecting many organs including the brain due to multiple mediators released by mast cells. These unique tissue immune cells are critical for allergic reactions triggered by immunoglobulin E (IgE), but are also [...]

Authors: Theoharides TC, Tsilioni I, Ren H PMID: 30884251 PMCID: PMC7003574 DOI: 10.1080/1744666X.2019.1596800 Abstract An increasing number of patients present with multiple symptoms affecting many organs including the brain due to multiple mediators released by mast cells. These unique tissue immune cells are critical for allergic reactions triggered by immunoglobulin E (IgE), but are also [...]

Auhtors: Wu T, Wu X, Wang HY, Chen L PMID: 30999966 PMCID: PMC6471962 DOI: 10.1186/s40880-019-0365-9 Abstract Tumor immune microenvironment is closely related to tumor initiation, prognosis, and response to immunotherapy. The immune landscapes, number of infiltrating immune cells, and the localization of lymphocytes in the tumor vary in across different types of tumors. The immune [...]

Auhtors: Kim SR, Kim K, Lee SA, Kwon SO, Lee JK, Keum N, Park SM PMID: 30979076 PMCID: PMC6520977 DOI: 10.3390/nu11040826 Abstract Whether the risk of gastric cancer varies by the types of meat consumption still remains disputable. The purpose of this meta-analysis was to identify the exact associations that red, processed, and white meat [...]