Authors: Hong J, Barnes MJ, Kessler NJ PMID: 23561872 DOI: 10.1016/j.jbmt.2012.08.007 Abstract The aim of the study was to describe a case of type II diabetic peripheral small fiber neuropathic pain treated with whole body vibration therapy after a failed trial of conventional drugs and interventional pain management. A 64-year-old male had chronic diabetic peripheral [...]

Authors: Gonzalez-Castejoxn M, Visioli F, Rodrigues-Casado A PMID: 22946853 DOI: 10.1111/j.1753-4887.2012.00509.x Abstract Dandelion (Taraxacum officinale Weber) is a member of the Asteraceae (Compositae) family, native to Europe but widely distributed in the warmer temperate zones of the Northern Hemisphere. Dandelion and its parts are habitually consumed as plant foods in several areas of the world, [...]

Authors: Booth NE, Myhill S, McLaren-Howard J PMID: 22837795 PMCID: PMC3403556 Abstract The objectives of this study are to test the hypothesis that the fatigue and accompanying symptoms of Chronic Myalgic Encephalomyelitis/Fatigue Syndrome are in part due to defects in energy provision at the cellular level, and to understand the pathophysiology of the defects so [...]

Authors: Misra HS, rajpurohit YS, Khairnar NP. PMID: 22581337 DOI: 10.1007/s12038-012-9195-5 Abstract Pyrroloquinoline-quinine (PQQ) was initially characterized as a redox cofactor for membrane-bound dehydrogenases in the bacterial system. Subsequently, PQQ was shown to be an antioxidant protecting the living cells from oxidative damage in vivo and the biomolecules from artificially produced reaction oxygen species in [...]

Authors: Nicolson GL, Settineri R, Ellithorpe R DOI: 10.4236/ijcm.2012.33034 Abstract Objectives: A preliminary open label study was initiated to determine if a combination oral supplement containing a mixture of phosphoglycolipids, coenzyme Q10 and microencapsulated NADH could affect fatigue levels in long-term patients with intractable fatigue. Fatigue was determined by the validated Piper Fatigue Scale before, [...]

Authors: Weng Z, Zhang B, Asadi S, Sismanopoulos N, Butcher A. PMID: 22470478 PMCID: PMC3314669 DOI: 10.1371/journal.pone.0033805 Abstract Mast cells are immune cells critical in the pathogenesis of allergic, but also inflammatory and autoimmune diseases through release of many pro-inflammatory cytokines such as IL-8 and TNF. Contact dermatitis and photosensitivity are skin conditions that involve [...]

Authors: Wu C, Li A, Leng Y, Kang J PMID: 22054065 DOI: 10.1089/dna.2011.1401 Abstract Recent studies suggest that change of macrophage phenotype (M1/M2) is associated with autoimmune diseases. Sodium valproate (VPA) is a class I histone deacetylase (HDAC) inhibitor, which has immunomodulatory function in graft-versus-host disease. However, its impact on macrophage polarization has not been [...]

Authors: Wikramanayake TC, Villasante AC, Mauro LM, Perez CI, Jimenez JJ PMID: 22042611 PMCID: PMC3273564 DOI: 10.1007/s12192-011-0305-3 Abstract Alopecia areata (AA) is an autoimmune non-scarring hair loss disorder. AA can be acute, recurrent, or chronic. Current therapeutic options for AA are limited, and there is no effective prevention for recurrent AA. We have previously shown [...]

Authors: Allen J, Bradley RD PMID: 21875351 PMCID: PMC3162377 DOI: 10.1089/acm.2010.0716 Abstract Background: The tripeptide glutathione (GSH) is the most abundant free radical scavenger synthesized endogenously in humans. Increasing mechanistic, clinical, and epidemiological evidence demonstrates that GSH status is significant in acute and chronic diseases. Despite ease of delivery, little controlled clinical research data exist [...]

Authors: Clarke JD, Hsu A, Riedl K, Bella D, Stevens JF, Ho E PMID: 21816223 PMCID: PMC3183106 DOI: 10.1016/j.phrs.2011.07.005 Abstract Broccoli consumption may reduce the risk of various cancers and many broccoli supplements are now available. The bioavailability and excretion of the mercapturic acid pathway metabolites isothiocyanates after human consumption of broccoli supplements has not [...]