Authors: Akagawa M, Nakano M, Ikemoto K PMID: 26168402 DOI: 10.1080/09168451.2015.1062715 Abstract Pyrroloquinoline quinone (PQQ), an aromatic tricyclic o-quinone, was identified initially as a redox cofactor for bacterial dehydrogenases. Although PQQ is not biosynthesized in mammals, trace amounts of PQQ have been found in human and rat tissues because of its wide distribution in dietary [...]

Authors: Misra HS, rajpurohit YS, Khairnar NP. PMID: 22581337 DOI: 10.1007/s12038-012-9195-5 Abstract Pyrroloquinoline-quinine (PQQ) was initially characterized as a redox cofactor for membrane-bound dehydrogenases in the bacterial system. Subsequently, PQQ was shown to be an antioxidant protecting the living cells from oxidative damage in vivo and the biomolecules from artificially produced reaction oxygen species in [...]

Authors: Chowanadisiai W, Bauerly KA, Tchaparian E, Wong A, Rucker RB PMID: 19861415 PMCID: PMC2804159 DOI: 10.1074/jbc.M109.030130 Abstract Bioactive compounds reported to stimulate mitochondrial biogenesis are linked to many health benefits such increased longevity, improved energy utilization, and protection from reactive oxygen species. Previously studies have shown that mice and rats fed diets lacking in [...]