Auhtors: Debebe A, Medina V, Chen CY, Mahajan IM, Jia C, Fu D, et al. PMID: 34591416 PMCID: PMC8958883 DOI: 10.20892/j.issn.2095-3941.2021.0306 Abstract The Wnt/β-catenin signaling pathway regulates many aspects of tumor biology, and many studies have focused on the role of this signaling pathway in tumor cells. However, it is now clear that tumor development [...]

Auhtors: Cheah KL, Norhayati MN, Husniati Yaacob L, Abdul Rahman R PMID: 34559859 PMCID: PMC8462692 DOI: 10.1371/journal.pone.0257843 Abstract Objective: To determine the effect of Ashwagandha extract on sleep. Methods: A comprehensive search was conducted in CENTRAL, MEDLINE, SCOPUS, Google Scholars, World Health Organization Trials Portal, ClinicalTrials.gov, Clinical Trial Registry of India, and AYUSH Research Portal [...]

Auhtors: Astrup A, Teicholz N, Magkos F, Bier DM, Brenna JT, King JC, Mente A PMID: 34684304 PMCID: PMC8541481 DOI: 10.3390/nu13103305 Abstract The last decade has seen nearly 20 papers reviewing the totality of the data on saturated fats and cardiovascular outcomes, which, altogether, have demonstrated a lack of rigorous evidence to support continued recommendations [...]

Auhtors: Barclay AW, Augustin LS, Brighenti F, Delport E, Henry CJ, Sievenpiper JL, Yuexin Y PMID: 34579120 PMCID: PMC8466312 DOI: 10.3390/nu13093244 Abstract The glycaemic index (GI) is a food metric that ranks the acute impact of available (digestible) carbohydrates on blood glucose. At present, few countries regulate the inclusion of GI on food labels even [...]

Auhtors: Propovic KJ, Popvic DJ, Miljkovic D, Popvic JK, Lalosevic D, Posa M, Capo I PMID: 34536762 DOI: 10.1016/j.biopha.2021.112168 Abstract We investigated the anticancer effect of disulfiram and metformin combination on fibrosarcoma in hamsters. Hamsters of both sexes (~ 70 g) were randomly allocated to control and experimental groups (8 animals per group). In all [...]

Authors: McLelland J Abstract In this revised second edition, the author includes her ferroptosis protocol, an anticancer weapon using old drugs, a special diet, exercise and supplements. As in the original edition of this book, the author elaborates on her own struggle with cancer and relates the discoveries she made along the way. The book [...]

Auhtors: Farvid MS, Sidahmed E, Spence ND, Mante AK, Rosner BA, Barnett JB PMID: 34455534 DOI: 10.1007/s10654-021-00741-9 Abstract Red meat and processed meat consumption has been hypothesized to increase risk of cancer, but the evidence is inconsistent. We performed a systematic review and meta-analysis of prospective studies to summarize the evidence of associations between consumption [...]

Auhtors: Abbasi F, Lamendola C, Harris CS, Harris V, Tsai M-S, Tripathi P, et al. PMID: 34433298 PMCID: PMC8551023 DOI: 10.1161/ATVBAHA.121.316159 Abstract Objective: Statin treatment reduces the risk of atherosclerotic cardiovascular disease but is associated with a modest increased risk of type 2 diabetes, especially in those with insulin resistance or prediabetes. Our objective was [...]

Auhtors: Qin W-M, Wang K, Huang J-R, Mei X-L, Zhi Z doi: https://doi.org/10.6000/1929- Abstract Phosphodiesterase is an enzyme that degrades the phosphodiester bond in the second messenger molecules cAMP and cGMP, and regulates the localization, duration, and amplitude of cyclic nucleotide signaling within subcellular domains. Sildenafil is a potent and selective inhibitor of the type [...]

Auhtors: Welsh J, Bak MJ, Narvaez CJ PMID: 36028390 PMCID: PMC9509427 DOI: 10.1016/j.molmed.2022.07.002 Abstract Phylloquinone (vitamin K1) and menaquinones (vitamin K2 family) are essential for post-translational γ-carboxylation of a small number of proteins, including clotting factors. These modified proteins have now been implicated in diverse physiological and pathological processes including cancer. Vitamin K intake has [...]