Auhtors: Li X, Liu R, Su X, Pan Y, Han X, Shao C, Shi Y PMID: 31805946 PMCID: PMC6894344 DOI: 10.1186/s12943-019-1102-3 Abstract Cancer immunotherapies that engage immune cells to fight against tumors are proving to be powerful weapons in combating cancer and are becoming increasingly utilized in the clinics. However, for the majority of patients [...]

Auhtors: Lundt A, Jentschke E PMID: 30791735 PMCID: PMC7240880 DOI: 10.1177/1534735418822096 Abstract Background: Symptoms of anxiety, depression, and cancer-related fatigue are commonly associated with cancer. Cancer patients increasingly use complementary and alternative treatments, such as yoga, to cope with psychological and physical impairments. In the present article, long-term changes of anxiety, depression, and fatigue in [...]

Auhtors: Agrawal S, Wozniak M, Luc M, Makuch S, Pielka E, Agrawal AK, et al. PMID: 31719636 PMCID: PMC6851401 DOI: 10.1038/s41598-019-53145-x Abstract The present state of cancer chemotherapy is unsatisfactory. New anticancer drugs that marginally improve the survival of patients continue to be developed at an unsustainably high cost. The study aimed to elucidate the [...]

Auhtors: Tian Y, Song W, Li D, Cai L, Zhao Y PMID: 31802896 PMCID: PMC6802539 DOI: 10.2147/OTT.S213043 Abstract Resveratrol, as a natural product compound, has been recently attracted much attention for its potent effects on cancer. Cancer is a serious disease threatening human survival and social development. Autophagy is a cellular pathway to realize the [...]

Auhtors: Gok Metin Z, Karadas C, Izgu N, Ozdemir L, Demirci U PMID: 31520865 DOI: 10.1016/j.ejon.2019.09.003 Abstract Purpose: This study aimed to investigate the effects of progressive muscle relaxation (PMR) and mindfulness meditation (MM) on fatigue, coping styles, and quality of life (QOL) in patients with early breast cancer receiving adjuvant paclitaxel. Methods: The participants [...]

Auhtors: Lopresti AL, Smith SJ, Malvi H, Kodgule R PMID: 31517876 PMCID: PMC6750292 DOI: 10.1097/MD.0000000000017186 Abstract Background: Ashwagandha (Withania somnifera (L.) Dunal) is a herb traditionally used to reduce stress and enhance wellbeing. The aim of this study was to investigate its anxiolytic effects on adults with self-reported high stress and to examine potential mechanisms [...]

Auhtors: Cornet-Masana JM, Banús-Mulet A, Carbó JM, Torrente MÁ, Guijarro F, Cuesta-Casanovas L, et al. PMID: 31473184 PMCID: PMC6796581 DOI: 10.1016/j.ebiom.2019.08.021 Abstract Background: Despite great efforts to identify druggable molecular targets for AML, there remains an unmet need for more effective therapies. Methods: An in silico screening was performed using Connectivity Maps to identify FDA-approved [...]

Auhtors: Amaravadi RK, Kimmelman AC, Debnath J PMID: 31434711 PMCID: PMC7306856 DOI: 10.1158/2159-8290.CD-19-0292 Abstract Autophagy, a multistep lysosomal degradation pathway that supports nutrient recycling and metabolic adaptation, has been implicated as a process that regulates cancer. Although autophagy induction may limit the development of tumors, evidence in mouse models demonstrates that autophagy inhibition can limit [...]

Auhtors: Yin Z, Ma T, Huang B, Lin L, Zhou Y, Yan J, et al. PMID: 31307515 PMCID: PMC6631643 DOI: 10.1186/s13046-019-1313-x Abstract Background: Exosomes from cancer cells or immune cells, carrying bio-macromolecules or microRNAs (miRNAs), participate in tumor pathogenesis and progression by modulating microenvironment. Our study aims to investigate the role of these microRNA-501-3p (miR-501-3p) [...]

Auhtors: Chazelas E, Srour B, Desmetz E, Kesse-Guyot E, Julia C, Deschamps V, et al. PMID: 31292122 PMCID: PMC6614796 DOI: 10.1136/bmj.l2408 Abstract Objective: To assess the associations between the consumption of sugary drinks (such as sugar sweetened beverages and 100% fruit juices), artificially sweetened beverages, and the risk of cancer. Design: Population based prospective cohort [...]