Authors: Yang R, Li X, Liu H, Zhen Y, Zhang X, Xiong Q et al. PMID: 33778560 PMCID: PMC7233443 DOI: 10.1148/ryct.2020200047 Abstract Purpose: To evaluate the value of chest CT severity score (CT-SS) in differentiating clinical forms of coronavirus disease 2019 (COVID-19). Materials and methods: A total of 102 patients with COVID-19 confirmed by a [...]

Authors: Zhang C, Wu Z, Li JW, Zhao H, Wang GQ PMID: 32234467 PMCID: PMC7118634 DOI: 10.1016/j.ijantimicag.2020.105954 Abstract Since December 2019, a viral pneumonia, named coronavirus disease 2019 (COVID-19), from Wuhan, China, has swept the world. Although the case fatality rate is not high, the number of people infected is large and there is still [...]

Authors: Das UN PMID: 32229155 PMCID: PMC7270578 doi: 10.1016/j.arcmed.2020.03.004 Abstract SARS-CoV-2, SARS and MERS are all enveloped viruses that can cause acute respiratory syndrome. Arachidonic acid (AA) and other unsaturated fatty acids (especially eicosapentaenoic acd, EPA and docosahexaenoic acid DHA) are known to inactivate enveloped viruses and inhibit proliferation of various microbial organisms. The pro-inflammatory [...]

Authors: Cheng RZ PMID: 32328576 PMCID: PMC7167497 DOI: 10.1016/j.medidd.2020.100028 Abstract The COVID-19 (SARS-2-Cov) pandemic, first reported in Wuhan, China, is now spreading to many continents and countries, causing a severe public health burden. Currently, there is no vaccine or specific antiviral drug for this deadly disease. A quick, deployable and accessible, effective and safe treatment [...]

Auhtors: Cassetta L, Pollard JW PMID: 32208142 DOI: 10.1016/j.cub.2020.01.031 Abstract Cassetta and Pollard introduce tumor-associated macrophages and discuss their origin, diversity, function and plasticity. Keywords: tumor, tumor-associated macrophages Source: https://pubmed.ncbi.nlm.nih.gov/32208142/ Archive: https://archive.is/HUVcb

Authors: Ma KL, Liu ZH, Cao CF, Liu MK, Liao J doi: https://doi.org/10.1101/2020.03.19.20034124 Abstract Background Notwithstanding the clinical hallmarks of COVID-19 patients were reported, several critical issues still remain mysterious, i.e., prognostic factors for COVID-19 including extrinsic factors as viral load of SARS-CoV-2 and intrinsic factors as individual’s health conditions; myocarditis [...]

Authors: Iglesias J, Vassallo AV, Patel V, Sullivan JB, Cavanaugh J, Elbaga Y PMID: 32194058 DOI: 10.1016/j.chest.2020.02.049 Abstract Background: Sepsis is a major public health burden resulting in 25% to 30% in-hospital mortality and accounting for over 20 billion dollars of US hospital costs. Research question: Does hydrocortisone, ascorbic acid, thiamine (HAT) therapy improve clinical [...]

Authors: Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ PMID: 32192578 PMCID: PMC7270045 DOI: 10.1016/S0140-6736(20)30628-0 Abstract As of March 12, 2020, coronavirus disease 2019 (COVID-19) has been confirmed in 125 048 people worldwide, carrying a mortality of approximately 3·7%,1 compared with a mortality rate of less than 1% from influenza. There [...]

Authors: Zhou Y, Fu B, Zheng X, Wang D, Zhao C PMID: 34676125 PMCID: PMC7108005 DOI: 10.1093/nsr/nwaa041 Abstract Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV (SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity and mortality [1,2]. Recently, a severe pneumonia-associated respiratory syndrome caused by a new coronavirus (SARS-CoV-2) [...]

Authors: Spyropoulos AC, Lipardi C, Xu J, Peluso C, Spiro TE PMID: 32190813 PMCID: PMC7069762 DOI: 10.1055/s-0040-1705137 Abstract An individualized approach to identify acutely ill medical patients at increased risk of venous thromboembolism (VTE) and a low risk of bleeding to optimize the benefit and risk of extended thromboprophylaxis (ET) is needed. The International Medical [...]