Auhtors: Chazelas E, Srour B, Desmetz E, Kesse-Guyot E, Julia C, Deschamps V, et al. PMID: 31292122 PMCID: PMC6614796 DOI: 10.1136/bmj.l2408 Abstract Objective: To assess the associations between the consumption of sugary drinks (such as sugar sweetened beverages and 100% fruit juices), artificially sweetened beverages, and the risk of cancer. Design: Population based prospective cohort [...]

Auhtors: Ohue Y, Nishikawa H PMID: 31102428 PMCID: PMC6609813 DOI: 10.1111/cas.14069 Abstract Regulatory T (Treg) cells suppress abnormal/excessive immune responses to self- and nonself-antigens to maintain immune homeostasis. In tumor immunity, Treg cells are involved in tumor development and progression by inhibiting antitumor immunity. There are several Treg cell immune suppressive mechanisms: inhibition of costimulatory [...]

Auhtors: Manson JE, Cook NR, Lee IM, Christen W, Bassuk SS, Mora S, et al. PMID: 30415629 PMCID: PMC6425757 DOI: 10.1056/NEJMoa1809944 Abstract Background: It is unclear whether supplementation with vitamin D reduces the risk of cancer or cardiovascular disease, and data from randomized trials are limited. Methods: We conducted a nationwide, randomized, placebo-controlled trial, with [...]

Auhtors: Yang T, Qiao Y, Xiang S, Li W, Gan Y, Chen Y PMID: 30484859 DOI: 10.1002/ijc.31955 Abstract Epidemiological studies have explored the relationship between work stress and the risk of cancer, but it remains unclear on whether work stress could increase the risk of cancer, or by other factors such as smoking and physical [...]

Auhtors: Chen Y, Tan F, Wei L, Li X, Lyu Z, Feng X, et al. PMID: 30463535 PMCID: PMC6249821 DOI: 10.1186/s12885-018-5025-y Abstract Background: The effect of sleep duration on cancer risk remains controversial. We aimed to quantify the available evidence on this relationship using categorical and dose-response meta-analyses. Methods: Population-based cohort studies and case-control studies [...]

Authors: Xu R, Ji Z, Xu C, Zhu J PMID: 30431566 PMCID: PMC6257684 doi: 10.1097/MD.0000000000012912 Abstract Background: Autophagy is a mechanism which relies on lysosomes for clearance and recycling of abnormal proteins or organelles. Many studies have demonstrated that the deregulation of autophagy is associated with the development of various diseases including cancer. The use [...]

Auhtors: Puar YR, Shanmugam MK, Fan L, Arfuso F, Sethi G, Tergaonkar V PMID: 30060453 PMCID: PMC6163404 DOI: 10.3390/biomedicines6030082 Abstract Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is responsible for the regulation of a large number of genes that are involved in important physiological processes, including survival, inflammation, and immune responses. At the same [...]

Authors: Beljanski S Abstract A new breakthrough book, Winning the War on Cancer:The Epic Journey Towards a Natural Cure reveals the visionary discoveries of a French scientist whose suppressed research led to improvements in the prevention and treatment of cancer...naturally and without toxicity.This book is a "story within a story" as through its pages, Sylvie [...]

Auhtors: Fiolet T, Srour B, Sellem L, Kesse-Guyot E, Allès B, Méjean C, et al. PMID: 29444771 PMCID: PMC5811844 DOI: 10.1136/bmj.k322 Abstract Objective: To assess the prospective associations between consumption of ultra-processed food and risk of cancer. Design: Population based cohort study. Setting and participants: 104 980 participants aged at least 18 years (median age [...]

Authors: Mokhtari RB, Baluch N, Homayouni TS, Kumar S, Yeger H PMID: 28735362 PMCID: PMC5842175 DOI: 10.1007/s12079-017-0401-y Abstract Cancer is a multi-stage process resulting from aberrant signaling pathways driving uncontrolled proliferation of transformed cells. The development and progression of cancer from a premalignant lesion towards a metastatic tumor requires accumulation of mutations in many regulatory [...]