About 3·7 billion doses of ivermectin have been distributed in mass drug administration (MDA) campaigns globally over the past 30 years. At 10–100 times higher than current human doses, ivermectin is a known teratogen in mammals. During these campaigns with recommended doses, pregnant women might be inadvertently exposed. We therefore aimed to evaluate the existing evidence for serious and non-serious adverse events after ivermectin exposure in pregnant women.

To investigate the association between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes, and parameters of immune function and mortality due to a SARS-CoV-2 infection.

Authors: Colunga Biancatelli RM, Berrill M, Marik PE PMID: 31852327 DOI: 10.1080/14787210.2020.1706483 Abstract There is a growing interest in the administration of vitamin C beyond the treatment of hypovitaminosis C in malnourished patients. This has been driven by a 2016 ‘before-after’ study which suggested a substantial survival benefit from a protocol that included hydrocortisone, ascorbic [...]

Authors: Nieman DC, Simonson A, Sakaguchi CA, Sha W, Blevins T. PMID: 31694152 doi: 10.3390/nu11112665 Abstract This randomized, double-blinded, crossover study measured the acute effect of ingesting a mixed flavonoid-caffeine (MFC) supplement compared to placebo (PL) on energy expenditure (EE) and fat oxidation (FATox) in a metabolic chamber with premenopausal women (n = 19, mean [...]

Authors:Winska K, Maczka W, Lyczko J, Szumny A. PMID:PMC6612361 doi: 10.3390/molecules24112130 Abstract Herbs and the essential oils derived from them have been used from the beginning of human history for different purposes. Their beneficial properties have been applied to mask unpleasant odors, attract the attention of other people, add flavor and aroma properties to prepared [...]

Authors:Schnitzler P. PMID:31234166 DOI: 10.1159/000501062 Abstract Infections with herpes simplex virus type (HSV)-1 and HSV-2 are distributed worldwide. Although standard therapies with acyclovir and other synthetic drugs are available, the safety and efficacy of these drugs are limited due to the development of drug resistance and adverse side effects. The literature on essential oils and [...]

Riva A, Ronchi M, Petrangolini G, Bosisio S, Allegrini P. PMID: 30328058 PMCID: PMC6418071 DOI: 10.1007/s13318-018-0517-3 Abstract Background and objectives: The importance of quercetin and flavonoids in the diet and as food supplements is well known, and literature studies support their potential use to treat several human diseases. Many beneficial properties have been described [...]

Authors: Reddy P, Edwards LR. PMID: 28471760 DOI: 10.1097/MJT.0000000000000538 Abstract Background: Vitamin D and magnesium (Mg) are some of the most studied topics in medicine with enormous implications for human health and disease. Majority of the adults are deficient in both vitamin D and magnesium but continue to go unrecognized by [...]

Authors: Marik PE PMID: 30441816 doi: 10.3390/nu10111762 Abstract Sepsis is a devastating disease that carries an enormous toll in terms of human suffering and lives lost. Over 100 novel pharmacologic agents that targeted specific molecules or pathways have failed to improve the outcome of sepsis. Preliminary data suggests that the combination of Hydrocortisone, Ascorbic Acid [...]

Authors: Nieman DC, Kay CD, Rathore AS, Grace MH, Strauch RC. PMID: 30423955 PMCID: PMC6267437 DOI: 10.3390/nu10111718 Abstract Using a randomized, double-blinded, placebo-controlled, parallel group design, this investigation determined if the combination of two weeks of flavonoid supplementation (329 mg/day, quercetin, anthocyanins, flavan-3-ols mixture) and a 45-minute walking bout (62.2 ± 0.9% VO2max (maximal oxygen [...]