Auhtors: Chang ET, Delzell E PMID: 27015139 PMCID: PMC4866614 DOI: 10.1080/03601234.2016.1142748 Abstract This systematic review and meta-analysis rigorously examines the relationship between glyphosate exposure and risk of lymphohematopoietic cancer (LHC) including NHL, Hodgkin lymphoma (HL), multiple myeloma (MM), and leukemia. Meta-relative risks (meta-RRs) were positive and marginally statistically significant for the association between any versus [...]

Auhtors: Wang Z, Jensen MA, Zenklusen JC PMID: 27008012 DOI: 10.1007/978-1-4939-3578-9_6 Abstract The Cancer Genome Atlas (TCGA) is one of the most ambitious and successful cancer genomics programs to date. The TCGA program has generated, analyzed, and made available genomic sequence, expression, methylation, and copy number variation data on over 11,000 individuals who represent over [...]

Auhtors: Erren TC, Morfeld P, Foster RG, Reiter RJ, Groß JV, Westermann IK PMID: 27003385 DOI: 10.3109/07420528.2016.1149486 Abstract Sleep and its impact on physiology and pathophysiology are researched at an accelerating pace and from many different angles. Experiments provide evidence for chronobiologically plausible links between chronodisruption and sleep and circadian rhythm disruption (SCRD), on the [...]

Auhtors: Temel JS, Abernethy AP, Currow DC, Friend J, Duus EM, Yan Y, Fearon KC PMID: 26906526 DOI: 10.1016/S1470-2045(15)00558-6 Abstract Background: Patients with advanced cancer frequently experience anorexia and cachexia, which are associated with reduced food intake, altered body composition, and decreased functionality. We assessed anamorelin, a novel ghrelin-receptor agonist, on cachexia in patients with [...]

Auhtors: Liu Y, Wheaton AG, Chapman DP, Cunningham TJ, Lu H, Croft JB PMID: 26890214 DOI: 10.15585/mmwr.mm6506a1 Abstract To promote optimal health and well-being, adults aged 18-60 years are recommended to sleep at least 7 hours each night (1). Sleeping <7 hours per night is associated with increased risk for obesity, diabetes, high blood pressure, [...]

Auhtors: Betrán AP, Ye J, Moller AB, Zhang J, Gülmezoglu AM, Torloni MR PMID: 26849801 PMCID: PMC4743929 DOI: 10.1371/journal.pone.0148343 Abstract Background: Caesarean section (CS) rates continue to evoke worldwide concern because of their steady increase, lack of consensus on the appropriate CS rate and the associated additional short- and long-term risks and costs. We present [...]

Auhtors: Benbrook CM PMID: 27752438 PMCID: PMC5044953 DOI: 10.1186/s12302-016-0070-0 Abstract Background: Accurate pesticide use data are essential when studying the environmental and public health impacts of pesticide use. Since the mid-1990s, significant changes have occurred in when and how glyphosate herbicides are applied, and there has been a dramatic increase in the total volume applied. [...]

Auhtors: Schreder ED, Uding N, La Guardia MJ. PMID: 26775187 DOI: 10.1016/j.chemosphere.2015.11.084 Abstract Chlorinated organophosphate flame retardants (ClOPFRs) are widely used as additive flame retardants in consumer products including furniture, children's products, building materials, and textiles. Tests of indoor media in homes, offices, and other environments have shown these compounds are released from products and [...]

Auhtors: Gallego-Ortega D, Ledger A, Roden DL, Law AM, Magenau A, Kikhytyak Z, Cho C PMID: 26717410 PMCID: PMC4696735 DOI: 10.1371/journal.pbio.1002330 Abstract During pregnancy, the ETS transcription factor ELF5 establishes the milk-secreting alveolar cell lineage by driving a cell fate decision of the mammary luminal progenitor cell. In breast cancer, ELF5 is a key transcriptional [...]

Auhtors: Becht E, Giraldo NA, Dieu-Nosjean MC, Sautès-Fridman C, Fridman WH PMID: 26708937 DOI: 10.1016/j.coi.2015.11.009 Abstract The immune contexture that characterizes the density, the location, the organization and the functional orientation of tumor-infiltrating immune cells in cancers has a clinical impact on patient's outcome. It is, in great part, shaped by the malignant cells, as [...]