Authors: Castillo RR, Quizon GR, Juco MJ, Roman AD, de Leon DG, Punzalan FE et al. DOI:https://doi.org/https://doi.org/10.32794/mr11250063. Abstract Treatment for coronavirus disease 2019 (COVID19) pneumonia remains empirical and the search for therapies that can improve outcomes continues. Melatonin has been shown to have anti-inflammatory, antioxidant, and immune-modulating effects that may address key pathophysiologic mechanisms in [...]

Authors: Wang J, Wang Y, Zhou H, Gu W, Wang X, Yang J PMID: 32317585 DOI: 10.1097/MEG.0000000000001737 Abstract Objective: The aim of the study was to investigate the clinical efficacy and safety of ketotifen for the treatment of irritable bowel syndrome with diarrhea (IBS-D). Methods: A total of 108 enrolled IBS-D patients were randomly divided [...]

This article summarizes the likely benefits of melatonin in the attenuation of COVID-19 based on its putative pathogenesis.

Authors: Chowdhury AT, Shahbaz M, Karim MR, Islam J, Dan G DOI: 10.14744/ejmo.2021.16263 Abstract Objectives: We investigated the outcomes of Ivermectin-Doxycycline vs. Hydroxychloroquine-Azithromycin combination therapy in mild to moderate COVID19 patients. Methods: Patients were divided randomly into two groups: Ivermectin 200µgm/kg single dose + Doxycycline 100mg BID for ten days in group A, and Hydroxychloroquine [...]

Authors: Henriquez MS, de Tejada Romero MJ PMID: 32486496 PMCID: PMC7352679 doi: 10.3390/nu12061617 Abstract Vitamin D deficiency is a global health problem due to its high prevalence and its negative consequences on musculoskeletal and extra-skeletal health. In our comparative review of the two exogenous vitamin D supplementation options most used in our care setting, we [...]

Authors: Sharun K, Dhama K, Patel SK, Pathak M, Tiwari R PMID: 32473642 PMCID: PMC7261036 DOI: 10.1186/s12941-020-00368-w Abstract The recent report by Caly et al., describing the antiviral potential of ivermectin against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro arrive to the agenda of potential candidates for COVID-19 treatment. This discovery gave [...]

Authors: Jacobs JJ PMID: 32512289 PMCID: PMC7832094 DOI: 10.1016/j.mehy.2020.109884 Abstract SARS-CoV-2 is a novel beta-coronavirus causing over 200.000 lethal cases within six months of first infecting humans. SARS-CoV-2 causes COVID-19, a form of severe acute respiratory syndrome (SARS). COVID-19 is characterized by two phases: the first resembles the flu with pneumonia, but after about seven [...]

Authors: Liu J, Zheng X, Huang Y, Shan H, Huang J PMID: 32479759 PMCID: PMC7256545 DOI: 10.1016/j.jaci.2020.05.021 Abstract As of April 4, 2020, a total of 1,051,635 coronavirus disease 2019 (COVID-19) cases had been reported worldwide, among which 56,985 deaths occurred (5.42%).1 However, to date, no vaccine and no specific antiviral medicine are available to [...]

Authors: Unal G, Turan B, Balcioglu YH PMID: 32498007 PMCID: PMC7255327 DOI: 10.1016/j.mehy.2020.109891 Abstract Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) which leads to COVID-19, was first seen in Wuhan province of China in December 2019 and spread globally in a short time. COVID-19 was announced as a pandemic by WHO on March 11th, 2020 and approximately [...]

Authors: dos Santos LM. DOI: 10.30574/gscbps.2020.11.3.0155 Abstract COVID-19 has become an international pandemic and is causing a worldwide public health emergency; therefore, an effective treatment is urgently needed. The hypothesis is that Covid virus interferes with the cobalamin metabolism, causing symptoms of cobalamin deficiency. This is plausible to infer, because there are symptoms of vitamin [...]