Authors: Haymet A, Bassi GL, Fraser JF PMID: 33170330 PMCID: PMC7652914 DOI: 10.1007/s00134-020-06314-w Abstract In 2020, a new pandemic caused by SARS-CoV-2 was declared, and since the first cases of coronavirus disease 2019 (COVID-19), clinicians had to apply different modes of respiratory support, previously used on patients with severe respiratory failure from other etiologies. In [...]

Authors: Mandal S, Barnett J, Brill SE, Brown JS, Hare SS PMID: 33172844 PMCID: PMC7661378 DOI: 10.1136/thoraxjnl-2020-215818 Abstract Large numbers of people are being discharged from hospital following COVID-19 without assessment of recovery. In 384 patients (mean age 59.9 years; 62% male) followed a median 54 days post discharge, 53% reported persistent breathlessness, 34% cough [...]

Authors: Patterson BK, seethamraju H, Dhody K, Corley MJ, Kazempour K, Lalezari J et al. PMID: 33186704 PMCID: PMC7654230 DOI: 10.1016/j.ijid.2020.10.101 Abstract Objective: Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now a global pandemic. Emerging results indicate a dysregulated immune response. Given the role of CCR5 in immune cell migration and inflammation, [...]

Auhtors: Fung J Abstract Our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline . . . but the “War on Cancer” has hardly been won. In The Cancer Code, Dr. Jason Fung [...]

Auhtors: Dionisio MR, Vieira AF, Carvalho R, Conde I, Oliveira M, Gomes M, et al. PMID: 33182375 PMCID: PMC7695320 DOI: 10.3390/cells9112442 Abstract Brain metastases remain an unmet clinical need in breast oncology, being frequently found in HER2-overexpressing and triple-negative carcinomas. These tumors were reported to be highly cancer stem-like cell-enriched, suggesting that brain metastases probably [...]

Authors: Harvey CJ PMID: 33304703 PMCID: PMC7721078 DOI: 10.7759/cureus.11371 Abstract Alopecia areata (AA) is a common autoimmune condition resulting in spot baldness and, rarely, more extensive hair loss. There is an association between both the incidence and the severity of AA and several micronutrients, including vitamin D and zinc. This case reports an eight-year-old male [...]

Authors: Bagate F, Tuffet S, Masi P, Perier F, Razazi K PMID: 33150525 PMCID: PMC7641257 DOI: 10.1186/s13613-020-00769-2 Abstract Background: In COVID-19 patients with severe acute respiratory distress syndrome (ARDS), the relatively preserved respiratory system compliance despite severe hypoxemia, with specific pulmonary vascular dysfunction, suggests a possible hemodynamic mechanism for VA/Q mismatch, as hypoxic vasoconstriction alteration. [...]

Background Ivermectin is one among several potential drugs explored for its therapeutic and preventive role in COVID-19 infection. The study was aimed to explore the association between ivermectin prophylaxis and development of COVID-19 infection among healthcare workers.

Authors: Zuo Y, Estes SK, Ali RA, Gandhi AA, Shi H PMID: 33139519 PMCID: PMC7724273 DOI: 10.1126/scitranslmed.abd3876 Abstract Patients with COVID-19 are at high risk for thrombotic arterial and venous occlusions. Lung histopathology often reveals fibrin-based blockages in the small blood vessels of patients who succumb to the disease. Antiphospholipid syndrome is an acquired and [...]

Authors: McCoy J, Cadegiani FA, Wambler CG, Herrera S, Goren A PMID: 33135263 DOI: 10.1111/jdv.17021 Abstract We have previously reported that men with androgenetic alopecia (AGA) are more likely to present with severe COVID-19 symptoms, potentially implicating androgen sensitivity as a risk factor for COVID-19.1-3 As such, we hypothesized that 5-alpha-reductase inhibitors (5ARi) may reduce [...]