Auhtors: Tokita H, Tsuchida A, Miyazawa K, Ohyashiki K, Katayanagi S, Sudo H, et al. PMID: 16391821 Abstract Vitamin K2 (VK2) has a growth inhibitory effect on various types of cancer cells in vitro, and its efficacy has been demonstrated in clinical applications in a number of patients with leukemia and hepatocellular carcinoma. In this [...]

Authors: Zoger S, Svedlund J, Holgers KM PMID: 16415703 DOI: 10.1097/01.jcp.0000195111.86650.19 Abstract Objective: The relationship between tinnitus and anxiety and depressive disorders has been frequently alluded to, but there are few studies on antidepressants in the treatment of tinnitus, and the efficacy of sertraline on severe refractory tinnitus has not been reported. Method: Consecutive tinnitus [...]

Auhtors: Bettuzzi S, Brausi M, Rizzi F, Castagnetti G, Peracchia G, Corti A PMID: 16424063 DOI: 10.1158/0008-5472.CAN-05-1145 Abstract Green tea catechins (GTCs) proved to be effective in inhibiting cancer growth in several experimental models. Recent studies showed that 30% of men with high-grade prostate intraepithelial neoplasia (HG-PIN) would develop prostate cancer (CaP) within 1 year [...]

Auhtors: Huang B, Pan PY, Li Q, Sato AI, Levy DE, Bromberg J, et al. PMID: 16424049 DOI: 10.1158/0008-5472.CAN-05-1299 Abstract The accumulation of myeloid suppressor cells (MSCs) is associated with immune suppression in tumor-bearing mice and in cancer patients. The suppressive activity of MSC correlates with the expression of the myeloid markers Gr-1, CD115 (macrophage [...]

Authors: Elenkov IJ PMID: 15265778 DOI: 10.1196/annals.1321.010 Abstract Evidence accumulated over the last 5-10 years indicates that glucocorticoids (GCs) inhibit the production of interleukin (IL)-12, interferon (IFN)-gamma, IFN-alpha, and tumor necrosis factor (TNF)-alpha by antigen-presenting cells (APCs) and T helper (Th)1 cells, but upregulate the production of IL-4, IL-10, and IL-13 by Th2 cells. Through [...]

Authors: Bahmad FM, Venosa AR, Oliveira CA PMID: 17260879 Abstract Severe disabling tinnitus (SDT) refers to a symptom severe enough to disrupt affected patients' routine and keep them from performing their daily activities. SDT of a predominantly central origin has been treated successfully with benzodiazepines and GABAergic drugs. Our aim was to test the control [...]

Authors: Levenson CW PMID: 16491668 DOI: 10.1111/j.1753-4887.2006.tb00171.x Abstract Low serum zinc levels have been linked to major depression. Furthermore, zinc treatment has been shown to have an antidepressant effect. With the hope of understanding the role of zinc in mood disorders, recent work has begun to explore possible mechanisms of zinc action on serotonin uptake [...]

Authors: Ichikado K, Suga M, Muranka H, Gushima Y, Miyakawa H PMID: 16293804 DOI: 10.1148/radiol.2373041515 Abstract Purpose: To retrospectively evaluate whether the thin-section computed tomographic (CT) appearance has prognostic value for prediction of mortality, number of ventilator-free days (ie, days without mechanical ventilation), and 28-day risk of barotrauma in patients with a clinically early stage [...]

Authors: Nowak G, Szewczyk B, Pilc A PMID: 16382189 Abstract Unsatisfactory clinical efficacy and a variety of adverse effects of current antidepressant drugs have incited search for better therapy. Zinc, an antagonist of the glutamate/N-methyl-D-aspartate (NMDA) receptor, exhibits antidepressant-like activity in rodent tests/models of depression. Similarly to antidepressants, zinc induces brain derived neurotrophic factor (BDNF) [...]

Auhtors: Martin RM, Middleton N, Gunnell D, Owen CG, Smith GD PMID: 16204694 DOI: 10.1093/jnci/dji291 Abstract Background: Having been breast-fed has been suggested to influence cancer risk in adulthood. We investigated associations between breast-feeding during infancy and adult cancer incidence and mortality in a cohort study and meta-analyses of published studies. Methods: The Boyd Orr [...]