Auhtors: Tseng CH PMID: 30896668 PMCID: PMC6709307 DOI: 10.1097/MD.0000000000014955 Abstract Background: The relationship between metformin use and the risk of prostate cancer is still inconclusive. Therefore, we performed a systematic review and meta-analysis of all eligible cohort studies to evaluate a potential association of metformin use with prostate cancer risk. Methods: A comprehensive literature search [...]

Auhtors: Miyata Y, Shida Y, Hakariya T, Sakai H PMID: 30621039 PMCID: PMC6337309 DOI: 10.3390/molecules24010193 Abstract Prostate cancer is the most common cancer among men. Green tea consumption is reported to play an important role in the prevention of carcinogenesis in many types of malignancies, including prostate cancer; however, epidemiological studies show conflicting results regarding [...]

Auhtors: Kenfield SA, Stampfer MJ, Giovannucci E, Chan JM PMID: 21205749 PMCID: PMC3056656 DOI: 10.1200/JCO.2010.31.5226 Abstract Purpose: To determine whether higher physical activity after prostate cancer (PCa) diagnosis decreases risk of overall and PCa-specific death. Patients and methods: We evaluated physical activity in relation to overall and PCa mortality among 2,705 men in the Health [...]

Auhtors: Buschemeyer WC, Klink JC, Mavropoulos JC, Poulton SH, Hursting SD PMID: 20166128 DOI: 10.1002/pros.21136 Abstract Introduction: Caloric restriction (CR) delays cancer growth in animals, though translation to humans is difficult. We hypothesized intermittent fasting (i.e., intermittent extreme CR), may be better tolerated and prolong survival of prostate cancer (CaP) bearing mice. Methods: We conducted [...]

Auhtors: Mavropoulos JC, Buschemeyer WC, Tewari AK, Rokheld D, Pollak M, Zhao Y PMID: 19470786 PMCID: PMC3774034 DOI: 10.1158/1940-6207.CAPR-08-0188 Abstract Purpose: Numerous dietary factors elevate serum levels of insulin and insulin-like growth factor I (IGF-I), both potent prostate cancer mitogens. We tested whether varying dietary carbohydrate and fat, without energy restriction relative to comparison diets, [...]

Auhtors: Bonorden MJ, Rogozina OP, Kluczny CM, Grossmann ME, Grambsch PL, Grande JP, Perkins S PMID: 19235043 DOI: 10.1080/01635580802419798 Abstract Prostate cancer is the most frequently diagnosed cancer in men. Whereas chronic calorie restriction (CCR) delays prostate tumorigenesis in some rodent models, the impact of intermittent caloric restriction (ICR) has not been determined. Here, transgenic [...]

Auhtors: Bettuzzi S, Brausi M, Rizzi F, Castagnetti G, Peracchia G, Corti A PMID: 16424063 DOI: 10.1158/0008-5472.CAN-05-1145 Abstract Green tea catechins (GTCs) proved to be effective in inhibiting cancer growth in several experimental models. Recent studies showed that 30% of men with high-grade prostate intraepithelial neoplasia (HG-PIN) would develop prostate cancer (CaP) within 1 year [...]