Authors:te Velthuis AJ, van den Worm SH, Sims AC, Baric RS, Snijder EJ, van Hemert MJ. PMID:PMC2973827 Abstract Increasing the intracellular Zn2+ concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses, including poliovirus and influenza virus. For some viruses this effect has been attributed to interference with [...]

Authors: Duma D, Collins JB, Chou JW, Cidlowski JA PMID: 20940427 PMCID: PMC4772900 DOI: 10.1126/scisignal.2001077 Abstract Males and females show differences in the prevalence of many major diseases that have important inflammatory components to their etiology. These gender-specific diseases, which include autoimmune diseases, hepatocellular carcinoma, diabetes, and osteoporosis, are largely considered to reflect the actions [...]

Authors: Martinez-Devesda P, Waddell A, Perera R, Theodoulou M PMID: 20824844 DOI: 10.1002/14651858.CD005233.pub3 Abstract Background: This is an update of a Cochrane Review originally published in Issue 1, 2007 of The Cochrane Library.Tinnitus is an auditory perception that can be described as the experience of sound, in the ear or in the head, in the [...]

Auhtors: Brandi ML PMID: 22460535 PMCID: PMC3213838 Abstract Many arguments are favouring a renewed interest in vitamin D physiology, with a consequent increase in the number of scientific publications and media reports (1). Not surprisingly, TIME magazine nominated vitamin D as one of the “top medical breakthroughs” in the December issue of 2007. This vigorous [...]

Auhtors: Yoo JJ, Kim HY. DOI:10.1080/20932685.2010.10593069 Abstract The goal of this study is to 1) identify the types of beauty product used and to compare the frequency with which adolescent boys and girls use them; and 2) determine types of beauty product use are significant in relation to the degree of media influence among them [...]

Authors: Klooker TK, Braak B, Koopman KE, Welting O, Wouters MM, Schemann M PMID: 20650926 DOI: 10.1136/gut.2010.213108 Abstract Background: Mast cell activation is thought to be involved in visceral hypersensitivity, one of the main characteristics of the irritable bowel syndrome (IBS). A study was therefore undertaken to investigate the effect of the mast cell stabiliser [...]

Auhtors: Buschemeyer WC, Klink JC, Mavropoulos JC, Poulton SH, Hursting SD PMID: 20166128 DOI: 10.1002/pros.21136 Abstract Introduction: Caloric restriction (CR) delays cancer growth in animals, though translation to humans is difficult. We hypothesized intermittent fasting (i.e., intermittent extreme CR), may be better tolerated and prolong survival of prostate cancer (CaP) bearing mice. Methods: We conducted [...]

Authors: Finkelstein Y, Aks SE, Hutson JR, Juurlink DN, Nguyen P, Pollak U PMID: 20586571 DOI: 10.3109/15563650.2010.495348 Abstract Introduction: Colchicine is used mainly for the treatment and prevention of gout and for familial Mediterranean fever (FMF). It has a narrow therapeutic index, with no clear-cut distinction between nontoxic, toxic, and lethal doses, causing substantial [...]

Authors: Yan XM, Kim CH, Lee CK, Shin JS, Cho IH PMID: 20473377 PMCID: PMC2869457 DOI: 10.4196/kjpp.2010.14.2.71 Abstract To investigate the intestinal absorption of a fibrinolytic and proteolytic lumbrokinase extracted from Eisenia andrei, we used rat everted gut sacs and an in situ closed-loop recirculation method. We extracted lumbrokinase from Eisenia andrei, and then raised [...]

Auhtors: Baeke F, Takiishi T, Korf H, Gysemans C, Mathieu C PMID: 20427238 DOI: 10.1016/j.coph.2010.04.001 Abstract 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), the active form of vitamin D, is known to regulate calcium and phosphorus metabolism, thus being a key-player in bone-formation. However 1,25(OH)(2)D(3) also has a physiological role beyond its well-known role in skeletal homeostasis. Here, we [...]