Oxidative stress acutely increases the permeability of the vascular endothelium to large molecules that would not otherwise cross the barrier. Ascorbic acid is an antioxidant that tightens the endothelial permeability barrier, so we tested whether it might also prevent the increase in endothelial permeability due to cellular oxidative stress.

Authors: Yan S, Ci X, Chen N, Chen C, Li X, Chu X et al. PMID: 21279416 DOI: 10.1007/s00011-011-0307-8 Abstract Background and objective: Asthma is an inflammatory disease of the lungs that is characterised by increased inflammatory cell infiltration into the airways and poor respiratory function. Ivermectin is a semi-synthetic derivative of a family of [...]

Authors: Walle T PMID: 21261636 DOI: 10.1111/j.1749-6632.2010.05842.x Abstract This paper reviews our current understanding of the absorption, bioavailability, and metabolism of resveratrol, with an emphasis on humans. The oral absorption of resveratrol in humans is about 75% and is thought to occur mainly by transepithelial diffusion. Extensive metabolism in the intestine and liver results in [...]

Auhtors: Kenfield SA, Stampfer MJ, Giovannucci E, Chan JM PMID: 21205749 PMCID: PMC3056656 DOI: 10.1200/JCO.2010.31.5226 Abstract Purpose: To determine whether higher physical activity after prostate cancer (PCa) diagnosis decreases risk of overall and PCa-specific death. Patients and methods: We evaluated physical activity in relation to overall and PCa mortality among 2,705 men in the Health [...]

Auhtors: Wagan F, Memon GN Abstract for cesarean section, during 2003 and 2010, after a gap of 7 years and to evaluate, how the implementation of universally acceptable standards, affects rate of cesarean section without compromising maternal and fetal safety. Study Design: Comparative study. Place and Duration: Department of Obstetrics & Gynecology at People's Medical [...]

Authors: Cerutti A, Chen K, Chorny A PMID: 21219173 PMCID: PMC3064559 DOI: 10.1146/annurev-immunol-031210-101317 Abstract Mucosal surfaces are colonized by large communities of commensal bacteria and represent the primary site of entry for pathogenic agents. To prevent microbial intrusion, mucosal B cells release large amounts of immunoglobulin (Ig) molecules through multiple follicular and extrafollicular pathways. IgA [...]

Auhtors: Bartley J PMID: 21133662 DOI: 10.1586/eri.10.102 Abstract In the preantibiotic era, TB of the skin was treated successfully with UV light. By the 1920s, pulmonary TB was being treated with regular sun exposure. During the last decade, basic laboratory research into the antimicrobial actions of vitamin D has provided new insights into these historical [...]

In the preantibiotic era, TB of the skin was treated successfully with UV light. By the 1920s, pulmonary TB was being treated with regular sun exposure. During the last decade, basic laboratory research into the antimicrobial actions of vitamin D has provided new insights into these historical observations.

Authors: May JM, Qu ZC PMID: 21328627 PMCID: PMC3725122 DOI: 10.1002/biof.134 Abstract Oxidative stress acutely increases the permeability of the vascular endothelium to large molecules that would not otherwise cross the barrier. Ascorbic acid is an antioxidant that tightens the endothelial permeability barrier, so we tested whether it might also prevent the increase in endothelial [...]

Auhtors: Proietti S, Cucina A, D'Anselmi F, Dinicola S, Pasqualato A, Lisi E, Bizzarri M PMID: 21091766 DOI: 10.1111/j.1600-079X.2010.00824.x Abstract Melatonin and vitamin D3 inhibit breast cancer cell growth and induce apoptosis, but they have never been combined as a breast cancer treatment. Therefore, we investigated whether their association could lead to an enhanced anticancer [...]