Authors: Gassen NC, Papies J, Bajaj T, Emanuel J, Wechmann K, Heinz DE et al. doi: https://doi.org/10.1101/2020.04.15.997254 Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses an acute threat to public health and the world economy, especially because no approved specific drugs or vaccines are available. Pharmacological modulation of metabolism-dependent cellular pathways such as autophagy [...]

Authors: Caly L, Druce JD, Catton MG, Jans DA, Wagstaff KM. PMID: 32251768 PMCID: PMC7129059 DOI: 10.1016/j.antiviral.2020.104787 Abstract Although several clinical trials are now underway to test possible therapies, the worldwide response to the COVID-19 outbreak has been largely limited to monitoring/containment. We report here that Ivermectin, an FDA-approved anti-parasitic previously shown to have broad-spectrum [...]

Authors: Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y et al. PMID: 31986264 PMCID: PMC7159299 DOI: 10.1016/S0140-6736(20)30183-5 Abstract Background: A recent cluster of pneumonia cases in Wuhan, China, was caused by a novel betacoronavirus, the 2019 novel coronavirus (2019-nCoV). We report the epidemiological, clinical, laboratory, and radiological characteristics and treatment and [...]