Auhtors: Li M, Li C, Allen A, Stanley CA, Smith TJ PMID: 22079166 PMCID: PMC3294041 DOI: 10.1016/j.abb.2011.10.015 Abstract Glutamate dehydrogenase (GDH) is a homohexameric enzyme that catalyzes the reversible oxidative deamination of l-glutamate to 2-oxoglutarate. Only in the animal kingdom is this enzyme heavily allosterically regulated by a wide array of metabolites. The major activators [...]