Authors: Akbar AN, Gilroy DW PMID: 32675364 DOI: 10.1126/science.abb0762 Abstract Aging is associated with increased morbidity arising from a range of tissue dysfunctions. A common denominator of age-associated frailty is increased baseline inflammation, called inflammaging, that is present in older individuals. Recent studies have shown that the presence of excessive inflammation can inhibit immunity in [...]

Authors: Fontana F, Cazzato S, Giovanella S, Ballestri M, Leonelli M, Mori G PMID: 32838081 PMCID: PMC7363608 DOI: 10.1016/j.ekir.2020.07.008 Abstract Kidney dysfunction is frequently reported in patients with coronavirus disease 2019 (COVID-19). A recent large cohort study described an incidence of acute kidney injury (AKI) of 36% in patients who were hospitalized with COVID-19; AKI [...]

Authors: Zhang J, Meng G, Li W, Shi B, Dong H, Su Z PMID: 32664991 PMCID: PMC7359422 DOI: 10.1186/s12931-020-01440-x Abstract Background: In December 2019, the outbreak of a disease subsequently termed COVID-19 occurred in Wuhan, China. The number of cases increased rapidly and spread to six continents. However, there is limited information on the chest [...]

Authors: Chowdhury AT, Shahabz M, Karim MR, Islam J, Guo D, He D. DOI: https://doi.org/10.21203/rs.3.rs-38896/v1 Abstract Background The worldwide COVID-19 pandemic was caused by a newly discovered Coronavirus. The treatment methods for COVID-19 are emerging and rapidly evolving. Existing drugs, including Ivermectin and Hydroxychloroquine, offer the hope of effective treatment in early disease. In this [...]

Authors: Fakhar-e-Alam Kulyar M, Li R, Mehmood K, Waqas M, Li K, Li J PMID: 32773257 PMCID: PMC7347483 doi: 10.1016/j.phymed.2020.153277 Abstract The world is witnessing a difficult time. The race of developing a new coronavirus (COVID-19) vaccine is becoming more urgent. Many preliminary studies on the pathophysiology of COVID-19 patients have provided some clues to [...]

Authors: Alam MT, Murshed R, Bhiuyan E, Saber S, Alam RF, Robin RC. DOI:10.3329/jbcps.v38i0.47512 Abstract Background: A definitive treatment of SARS CoV-2 is yet toarrive and the human death toll rises exponentially globally.In this health emergency, it might be useful to look into theold therapies which could be effective against the virus. Invitro research showed [...]

Authors: Maurya DK DOI: 10.26434/chemrxiv.12630539.v1 D O I: 10.26434/chemrxiv.12630539.v1 [opens in a new tab] Abstract The current outbreak of the corona virus disease 2019 (COVID-19), has affected almost entire world and become pandemic now. Currently, there is neither any FDA approved drugs nor any vaccines available to control it. Very recently in Bangladesh, a group [...]

Authors: Carfi A, Bernabei R, Landi F doi:10.1001/jama.2020.12603 Abstract In Italy, a large proportion of patients with coronavirus disease 2019 (COVID-19) presented with symptoms (71.4% of 31 845 confirmed cases as of June 3, 2020).1 Common symptoms include cough, fever, dyspnea, musculoskeletal symptoms (myalgia, joint pain, fatigue), gastrointestinal symptoms, and anosmia/dysgeusia.2-4 However, information is lacking on [...]

Authors: Santamarina MG, Boisier D, Contreras R, Baque M, Volpacchio M PMID: 32631389 PMCID: PMC7338110 DOI: 10.1186/s13054-020-03125-9 Abstract In December 2019, a novel human coronavirus, SARS-CoV-2, was detected in the city of Wuhan, China, which since then has expanded throughout the world and caused a pandemic coronavirus disease (COVID-19). SARS-CoV-2 binds to angiotensin-converting enzyme 2 [...]

Authors: Francone M, Lafrate F, Masci GM, Coco S, Cilia F, Manganaro L et al. PMID: 32623505 PMCID: PMC7334627 DOI: 10.1007/s00330-020-07033-y Abstract Objectives: To correlate a CT-based semi-quantitative score of pulmonary involvement in COVID-19 pneumonia with clinical staging of disease and laboratory findings. We also aimed to investigate whether CT findings may be predictive of [...]