Authors: Wang W, Sun C, Mao L, Ma P, Liu F, Yang J. doi: https://doi.org/10.1016/j.tifs.2016.07.004 Abstract Background Quercetin, one of the most well-known flavonoids, has been included in human diet for a long history. The use of quercetin has been widely associated with a great number of health benefits, including antioxidant, anti-inflammatory, antiviral and anticancer [...]

Authors: Mogil RJ, Kaste SC, Ferry RJ, Hudson MM, Howell CR PMID: 26967465 PMCID: PMC4945422 DOI: 10.1001/jamaoncol.2015.6557 Abstract Importance: Bone accrual during youth is critical to establish sufficient strength for lifelong skeletal health. Children with cancer may develop low bone mineral density (BMD) any time before or after diagnosis. Objective: To evaluate the ability of [...]

Authors: Leyva-Lopez N, Gutierrez-Grijalva EP, Ambriz-Perez D. PMID: PMC4926454 DOI: 10.3390/ijms17060921 Abstract High levels of cytokines, such as interleukin (IL)-1β, tumor necrosis factor (TNF)-α and IL-6, are associated with chronic diseases like rheumatoid arthritis, asthma, atherosclerosis, Alzheimer's disease and cancer; therefore cytokine inhibition might be an important target for the treatment of these diseases. Most [...]

Authors: Karatas F, Sahin S, sever AR, Altundag K PMID: 27247882 PMCID: PMC4864803 DOI: 10.1186/s40064-016-2216-3 Abstract Endocrine therapy-induced hair loss (ETIHL) associated with aromatase inhibitors and tamoxifen treatment is currently mostly reported but remained an unresolved therapeutic issue in patients with breast cancer (BC) since the number of studies regarding the management is limited in [...]

Authors: Li Y, Yao J, Han C, Yang J, Chaudhry MT, Wang S et al. PMID: 26999194 doi: 10.3390/nu8030167 Abstract In vitro and some animal models have shown that quercetin, a polyphenol derived from plants, has a wide range of biological actions including anti-carcinogenic, anti-inflammatory and antiviral activities; as well as attenuating lipid peroxidation, platelet [...]

Authors: Verma D, Thompson J, Swaminathan S PMID: 26976570 PMCID: PMC4822607 DOI: 10.1073/pnas.1523686113 Abstract Clinically available drugs active against Epstein-Barr virus (EBV) and other human herpesviruses are limited to those targeting viral DNA replication. To identify compounds directed against other steps in the viral life cycle, we searched for drugs active against the EBV SM [...]

Authors: Gorres KL, Daigle D, Mohanram S, Mcinerney GE, Lyons DE PMID: 26933051 PMCID: PMC4810481 DOI: 10.1128/mBio.00113-16 Abstract Reactivation of Epstein-Barr virus (EBV) from latency into the lytic phase of its life cycle allows the virus to spread among cells and between hosts. Valproic acid (VPA) inhibits initiation of the lytic cycle in EBV-infected B [...]

Authors: Park D, Jeong H, Lee MN, Koh A, Kwon O, Yang YR et al. PMID: 26902888 PMCID: PMC4763238 DOI: 10.1038/srep21772 Abstract Resveratrol (RSV) is a natural polyphenol that has a beneficial effect on health, and resveratrol-induced autophagy has been suggested to be a key process in mediating many beneficial effects of resveratrol, such as [...]

Authors: Nicolson GL, Rosenblatt S, de Mattos GF, Settineri R, Breeding PC, Ash ME PMID: 32309576 PMCID: PMC6941554 DOI: 10.15190/d.2016.1 Abstract Membrane Lipid Replacement is the use of functional oral supplements containing cell membrane glycerolphospholipids and antioxidants to safely replace damaged membrane lipids that accumulate during aging and in various chronic and acute diseases. Most [...]

Authors: Dunlop K, Hanlon CA, Downar J PMID: 26849183 PMCID: PMC5434820 DOI: 10.1111/nyas.12985 Abstract Major depressive disorder (MDD) and substance use disorders (SUDs) are prevalent, disabling, and challenging illnesses for which new treatment options are needed, particularly in comorbid cases. Neuroimaging studies of the functional architecture of the brain suggest common neural substrates underlying MDD [...]