Authors: Andreu S, Ripa I, Bello-Morales R, Lopez-Guerrero JA PMID: 33256172 PMCID: PMC7760627 DOI: 10.3390/v12121356 Abstract Herpes simplex viruses (HSVs) are neurotropic viruses with broad host range whose infections cause considerable health problems in both animals and humans. In fact, 67% of the global population under the age of 50 are infected with HSV-1 and [...]

Authors: Ashraf S, Ashraf S, Ashraf M, Imran MA, Kalsoom L, Siddiqui UN et al. PMID: 36420866 DOI: 10.1002/ptr.7640 Abstract Until now, no specific and effective treatment exists for coronavirus disease 2019 (COVID-19). Since honey and Nigella sativa (HNS) have established antiviral, antibacterial, antiinflammatory, antioxidant, and immunomodulatory properties, we tested their efficacy for this disease [...]

Authors: Wood E, Hall KH, Tate W PMID: 33251031 PMCID: PMC7680046 DOI: 10.1016/j.cdtm.2020.11.002 Abstract A significant number of SARS-CoV-2 (COVID-19) pandemic patients have developed chronic symptoms lasting weeks or months which are very similar to those described for myalgic encephalomyelitis/chronic fatigue syndrome. This study reviews the current literature and understanding of the role that mitochondria, [...]

Authors: Harvey CJ PMID: 33304703 PMCID: PMC7721078 DOI: 10.7759/cureus.11371 Abstract Alopecia areata (AA) is a common autoimmune condition resulting in spot baldness and, rarely, more extensive hair loss. There is an association between both the incidence and the severity of AA and several micronutrients, including vitamin D and zinc. This case reports an eight-year-old male [...]

Authors: Zuo Y, Estes SK, Ali RA, Gandhi AA, Shi H PMID: 33139519 PMCID: PMC7724273 DOI: 10.1126/scitranslmed.abd3876 Abstract Patients with COVID-19 are at high risk for thrombotic arterial and venous occlusions. Lung histopathology often reveals fibrin-based blockages in the small blood vessels of patients who succumb to the disease. Antiphospholipid syndrome is an acquired and [...]

Authors: Shi Z, Puyo CA PMID: 33177829 PMCID: PMC7649937 DOI: 10.2147/TCRM.S273700 Abstract The novel coronavirus disease (COVID-19) is caused by a virus (SARS-Cov-2) and is known for inducing multisystem organ dysfunction associated with significant morbidity and mortality. Current therapeutic strategies for COVID-19 have failed to effectively reduce mortality rate, especially for elderly patients. A newly [...]

Authors: Balagholi S, Dabbaghi R, Eshghi P, Mousavi SA, Heshmati F, Mohammadi S PMID: 33162341 PMCID: PMC7605792 DOI: 10.1016/j.transci.2020.102993 Abstract Therapeutic plasmapheresis (TP) is the process of the separation and removal of plasma from other blood components and is considered as an adjunctive treatment strategy to the discarded abnormal agent in the management of respiratory [...]

Authors: Woodruff MC, Ramoneli RP, Lee FE, Sanz I doi: https://doi.org/10.1101/2020.10.21.20216192 Abstract Severe SARS-CoV-2 infection is linked to the presence of autoantibodies against multiple targets, including phospholipids and type-I interferons. We recently identified activation of an autoimmune-prone B cell response pathway as correlate of severe COVID-19, raising the possibility of de novo autoreactive antibody production [...]

Authors: Valizadeh H, Danshina S, Gencer MZ, Ammari A, Sadeghi A, Aslani S. PMID: PMC7574843 DOI: 10.1016/j.intimp.2020.107088 Abstract Background: As an ongoing worldwide health issue, Coronavirus disease 2019 (COVID-19) has been causing serious complications, including pneumonia, acute respiratory distress syndrome (ARDS), and multi-organ failure. However, there is no decisive treatment approach available for this disorder, [...]

Authors: Sanabria-Mazo JP, Montero-Marin J, Feliu-Soler A, Gasion V, Navarro-Gil M PMID: 33050630 PMCID: PMC7599726 DOI: 10.3390/jcm9103246 Abstract The lack of highly effective treatments for fibromyalgia (FM) represents a great challenge for public health. The objective of this parallel, pilot randomized controlled trial (RCT) was two-fold: (1) to analyze the clinical effects of mindfulness plus [...]