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References

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Cancer Care (474) I-CARE Early Covid (187) I-CARE Flu and RSV (36) I-PREVENT (153) I-RECOVER Long Covid (111) I-RECOVER Post-Vaccine (320) MATH+ (288)

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  • Reference: Anti-inflammatory potential of Quercetin in COVID-19 treatment.

    Published On: January 28, 2021

    Authors: Saeedi-Boroujeni A, Mahmoudian-Sani MR. PMID: Abstract SARS-CoV-2 is a betacoronavirus causing severe inflammatory pneumonia, so that excessive inflammation is considered a risk factor for the disease. According to reports, cytokine storm is strongly responsible for death in such patients. Some of the consequences of severe inflammation and cytokine storms include acute respiratory distress [...]

    Categories: I-CARE Early Covid, I-PREVENT, I-RECOVER Post-Vaccine

    Tags: COVID-19, quercetin

  • Reference: Sudomotor dysfunction in patients recovered from COVID-19.

    Published On: January 26, 2021

    Authors: Hinduja A, Moutairou A, Calvet JH PMID: 33551341 PMCID: PMC7835104 DOI: 10.1016/j.neucli.2021.01.003 Abstract Dysautonomia has been reported in COVID-19. Sweat function testing has been proposed to assess autonomic neuropathy. Fifty Indian patients consulting for neurological symptoms participated in this observational study. The NHS questionnaire for neurological symptoms was completed and electrochemical skin conductance was [...]

    Categories: I-RECOVER Post-Vaccine

    Tags: COVID-19, Sudomotor Dysfunction

  • Reference: COVID-19 and immunological dysregulation: can autoantibodies be useful?

    Published On: January 20, 2021

    Authors: Pascolini S, Vannini A, Deleonardi G, Ciordinik M, Sensoli A PMID: 32989903 PMCID: PMC7536986 DOI: 10.1111/cts.12908 Abstract Coronavirus disease 2019 (COVID-19) is often associated with interstitial pneumonia. However, there is insufficient knowledge on the presence of autoimmune serological markers in patients with COVID-19. We analyzed the presence and role of autoantibodies in patients with [...]

    Categories: I-RECOVER Post-Vaccine

    Tags: autoantibodies, COVID-19

  • Reference: Autophagy blockade mechanistically links proton pump inhibitors to worsened diabetic nephropathy and aborts the renoprotection of metformin/enalapril.

    Published On: January 15, 2021

    Authors: Mostafa DK, Khedr MM, Barakat MK, Abdellatif AA, Elsharkawy AM PMID: 33275985 DOI: 10.1016/j.lfs.2020.118818 Abstract Aim: Proton pump inhibitors (PPIs) are widely used drugs recently linked to chronic kidney disease. However, the invloved mechanisms remained elusive. Since defective autophagy is identified as a new culprit in the pathogenesis of diabetic nephropathy (DN), we aimed [...]

    Categories: I-RECOVER Post-Vaccine

    Tags: autophagy

  • Reference: Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post hospital discharge.

    Published On: January 7, 2021

    Authors: Raman B, Cassar MP, Tunnicliffe EM, Filippini N, Griffanti L, Okell T et al. PMID: 33490928 PMCID: PMC7808914 DOI: 10.1016/j.eclinm.2020.100683 Abstract Background: The medium-term effects of Coronavirus disease (COVID-19) on organ health, exercise capacity, cognition, quality of life and mental health are poorly understood. Methods: Fifty-eight COVID-19 patients post-hospital discharge [...]

    Categories: I-RECOVER Post-Vaccine

    Tags: SARS-CoV-2

  • Reference: COVID-19 and phosphodiesterase enzyme type 5 inhibitors.

    Published On: December 10, 2020

    Authors: Al-kuraishy HM, Ali-Gareeb AI, Al-Niemi MS, Buhadily AK PMID: 33623736 PMCID: PMC7883493 doi: 10.4103/JMAU.JMAU_63_20 Abstract COVID-19 pathology is mainly associated to a pulmonary disease which sometimes might result in an uncontrollable storm related to inflammatory diseases which could be fatal. It is well known that phosphodiesterase enzyme type 5 inhibitors (PDE5Is), such as sildenafil, [...]

    Categories: I-RECOVER Post-Vaccine

    Tags: COVID-19

  • Reference: Prognostic genetic markers for thrombosis in COVID-19 patients: A focused analysis on D-Dimer, homocysteine and thromboembolism.

    Published On: December 9, 2020

    Authors: Abu-Farha M, Al-Sabah S, Hammad MM, Hebbar P, John SE, Taher I et al. PMID: 33362545 PMCID: PMC7756688 DOI: 10.3389/fphar.2020.587451 Abstract COVID-19 is caused by Severe Acute Respiratory Syndrome Coronavirus-2, which has infected over thirty eight million individuals worldwide. Emerging evidence indicates that COVID-19 patients are at a high risk of developing coagulopathy and [...]

    Categories: I-RECOVER Post-Vaccine

    Tags: COVID-19, Homocysteine, Thrombosis

  • Reference: Plasmapheresis reduces cytokine and immune cell levels in COVID-19 patients with acute respiratory distress syndrome (ARDS).

    Published On: December 4, 2020

    Authors: Hashemian SM, Shafigh N, Afzal G, Jamaati H, Tabarsi P, Marjani M PMID: 33358260 PMCID: PMC7834188 DOI: 10.1016/j.pulmoe.2020.10.017 Abstract Background: In December 2019, pneumonia associated with a novel coronavirus (COVID-19) was reported in Wuhan, China. Acute respiratory distress syndrome (ARDS) is the most frequently observed complication in COVID-19 patients with high mortality rates. Objective [...]

    Categories: I-RECOVER Post-Vaccine

    Tags: acute respiratory distress syndrome, COVID-19, Cytokines, Plasmapheresis

  • Reference: Inhibitions of SARS-CoV 3CL protease by flavonoids.

    Published On: December 3, 2020

    Authors: Jo S, Kim S, Shin DH, Kim MS. PMID: 31724441 PMCID: PMC6882434 DOI: 10.1080/14756366.2019.1690480 Abstract There were severe panics caused by Severe Acute Respiratory Syndrome (SARS) and Middle-East Respiratory Syndrome-Coronavirus. Therefore, researches targeting these viruses have been required. Coronaviruses (CoVs) have been rising targets of some flavonoids. The antiviral activity of some flavonoids against [...]

    Categories: I-CARE Early Covid, I-PREVENT, I-RECOVER Post-Vaccine

    Tags: flavonoids

  • Reference: Plasma exchange: An effective rescue therapy in critically ill patients with Coronavirus Disease 2019 infection.

    Published On: December 1, 2020

    Authors: Fernandez J, Gratacos-Gines J, Olivas P, Costa M, Nieto S, Mateo D PMID: 32833695 PMCID: PMC7493773 DOI: 10.1097/CCM.0000000000004613 Abstract Objectives: Infection by severe acute respiratory syndrome coronavirus-2 can induce uncontrolled systemic inflammation and multiple organ failure. The aim of this study was to evaluate if plasma exchange, through the removal of circulating mediators, can [...]

    Categories: I-RECOVER Post-Vaccine, MATH+

    Tags: COVID-19, Therapeutic Plasma Exchange

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