Authors:Seneviratne CJ, Balan P, Ki KK, Udawatte NS, Lai D. PMID: PMC7734110 DOI: 10.1007/s15010-020-01563-9 Abstract Purpose: One of the key approaches to minimize the risk of COVID-19 transmission would be to reduce the titres of SARS-CoV-2 in the saliva of infected COVID-19 patients. This is particularly important in high-risk procedures like dental treatment. The present [...]

Authors:Gandolfi JV, Di Bernardo AP, Chanes DA, Martin DF, Joles VB, Amendola CP et al. PMID:33048904 DOI: 10.1097/CCM.0000000000004690 Abstract Objectives: To evaluate whether the use of exogenous melatonin affects sleep, reduces the prevalence of delirium, and decreases the need for analgosedation and to assess whether serum melatonin indices correlate with exogenous administration in critically ill [...]

Authors: Agrawal PK, Agrawal C, Blunden G. doi: https://doi.org/10.1177/1934578X20976293 Abstract Quercetin, a naturally occurring dietary flavonoid, is well known to ameliorate chronic diseases and aging processes in humans, and its antiviral properties have been investigated in numerous studies. In silico and in vitro studies demonstrated that quercetin can interfere with various stages of the coronavirus [...]

Authors: Jo S, Kim S, Shin DH, Kim MS. PMID: 31724441 PMCID: PMC6882434 DOI: 10.1080/14756366.2019.1690480 Abstract There were severe panics caused by Severe Acute Respiratory Syndrome (SARS) and Middle-East Respiratory Syndrome-Coronavirus. Therefore, researches targeting these viruses have been required. Coronaviruses (CoVs) have been rising targets of some flavonoids. The antiviral activity of some flavonoids against [...]

Authors:Hellwig MD, Maia A. PMID: PMC7698683 DOI: 10.1016/j.ijantimicag.2020.106248 Abstract As COVID-19 (coronavirus disease 2019) continues to rapidly spread throughout the world, the incidence varies greatly among different countries. These differences raise the question whether nations with a lower incidence share any medical commonalities that could be used not only to explain that lower incidence [...]

Authors: Ashraf S, Ashraf S, Ashraf M, Imran MA, Kalsoom L, Siddiqui UN et al. PMID: 36420866 DOI: 10.1002/ptr.7640 Abstract Until now, no specific and effective treatment exists for coronavirus disease 2019 (COVID-19). Since honey and Nigella sativa (HNS) have established antiviral, antibacterial, antiinflammatory, antioxidant, and immunomodulatory properties, we tested their efficacy for this disease [...]

Authors: Murai IH, Fernandes AL, Sales LP, Pinto AJ, Goessler KF. doi: https://doi.org/10.1101/2020.11.16.20232397 Abstract Importance Patients with COVID-19 may exhibit 25-hydroxyvitamin D deficiency, but the beneficial effects of vitamin D3 supplementation in this disease remain to be proven by randomized controlled trials. Objective To investigate the efficacy and safety of vitamin D3 supplementation in patients [...]

Authors: Din AU, Mazhar M, Waseem M, Ahmad w, Bibi A. PMID: 33197765 PMCID: PMC7657099 DOI: 10.1016/j.biopha.2020.110947 Abstract</h5 In December 2019, a pneumonia outbreak of unknown etiology was reported which caused panic in Wuhan city of central China, which was later identified as Coronavirus disease (COVID-19) caused by a novel coronavirus, Severe Acute Respiratory Syndrome [...]

Background Ivermectin is one among several potential drugs explored for its therapeutic and preventive role in COVID-19 infection. The study was aimed to explore the association between ivermectin prophylaxis and development of COVID-19 infection among healthcare workers.

Authors:Frank S, Brown SM, Capriotti JA, Westover JB, Pelletier JS. PMID: PMC7499242 DOI: 10.1001/jamaoto.2020.3053 Abstract Importance: Research is needed to demonstrate the efficacy of nasal povidone-iodine (PVP-I) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Objective: To evaluate the in vitro efficacy of PVP-I nasal antiseptic for the inactivation of SARS-CoV-2 at clinically significant contact [...]