Authors: Hoeger J, Simon TP, Beeker T, Marx G, Haase H. PMID: PMC5417428 DOI: 10.1371/journal.pone.0176069 Abstract Zinc is an essential trace element for both pathogens and hosts. Hypozincemia is a well known phenomenon in sepsis patients and represents the innate immune systems attempt to deprive pathogens of zinc. However little is known about course, restitution [...]

Authors:Hemila H. PMID: PMC5418896 DOI: 10.1177/2054270417694291 Abstract Objective: To compare the efficacy of zinc acetate lozenges with zinc gluconate lozenges in common cold treatment and to examine the dose-dependency of the effect. Design: Meta-analysis. Setting: Placebo-controlled zinc lozenge trials, in which the zinc dose was > 75 mg/day. The pooled effect of zinc lozenges on [...]

Authors: Rosa DD, Dias MM, Grzeskowiak LM, Reis SA. PMID: 28222814 DOI: 10.1017/S0954422416000275 Abstract Kefir is fermented milk produced from grains that comprise a specific and complex mixture of bacteria and yeasts that live in a symbiotic association. The nutritional composition of kefir varies according to the milk composition, the microbiological composition of the grains [...]

Authors: Rich GT. PMID: 28165426 doi: 10.3390/nu9020111 PMCID: PMC5331542 Abstract We have studied the uptake of quercetin aglycone into CaCo-2/TC7 cells in the presence and absence of mixed micelles that are present in the human small intestine. The micelles inhibited the transport of quercetin into the cells. To gain an understanding of why this is [...]

Authors: Zhang P, Tsuchiya K, Kinoshita T, Kushiyama H, Suidasari S, Hatakeyama M. PMID: 27733681 PMCID: PMC5114405 DOI: 10.1074/jbc.M116.743815 Abstract Vitamin B6 includes six water-soluble vitamers: pyridoxal (PL), pyridoxamine (PM), pyridoxine (PN), and their phosphorylated forms. Pyridoxal 5'-phosphate (PLP) is an important cofactor for many metabolic enzymes. Several lines of evidence demonstrate that blood levels [...]

Authors:Teng F, He T, Huang S, Bo CP, Li Z, Chang JL. PMID: PMC5113089 DOI: 10.1038/ijos.2016.18 Abstract Oral rinses containing chemotherapeutic agents, such as cetylpyridinium chloride (CPC), can alleviate plaque-induced gingival infections, but how oral microbiota respond to these treatments in human population remains poorly understood. Via a double-blinded, randomised controlled trial of 91 subjects, [...]

Authors: Rahimi HR, Nedaeinia R, Shamloo AS, Nikdoust S. PMID: 27516979 PMCID: PMC4967834 Abstract Objective: Curcumin is extracted from Curcuma longa and regulates the intracellular signal pathways which control the growth of cancerous cell, inflammation, invasion and apoptosis. Curcumin molecules have special intrinsic features that can target the intracellular enzymes, genome (DNA) and messengers (RNA). [...]

Authors: Wang W, Sun C, Mao L, Ma P, Liu F, Yang J. doi: https://doi.org/10.1016/j.tifs.2016.07.004 Abstract Background Quercetin, one of the most well-known flavonoids, has been included in human diet for a long history. The use of quercetin has been widely associated with a great number of health benefits, including antioxidant, anti-inflammatory, antiviral and anticancer [...]

Authors: Leyva-Lopez N, Gutierrez-Grijalva EP, Ambriz-Perez D. PMID: PMC4926454 DOI: 10.3390/ijms17060921 Abstract High levels of cytokines, such as interleukin (IL)-1β, tumor necrosis factor (TNF)-α and IL-6, are associated with chronic diseases like rheumatoid arthritis, asthma, atherosclerosis, Alzheimer's disease and cancer; therefore cytokine inhibition might be an important target for the treatment of these diseases. Most [...]

Authors: Li Y, Yao J, Han C, Yang J, Chaudhry MT, Wang S et al. PMID: 26999194 doi: 10.3390/nu8030167 Abstract In vitro and some animal models have shown that quercetin, a polyphenol derived from plants, has a wide range of biological actions including anti-carcinogenic, anti-inflammatory and antiviral activities; as well as attenuating lipid peroxidation, platelet [...]