Auhtors: Sobotka T PMID: 29160188 DOI: 10.1017/S0021932017000323 Abstract This study discusses fertility trends and variation in countries that completed the transition from high to around-replacement fertility in the 1950s to 1980s, especially in Europe, East Asia and North America, and summarizes the key relevant findings for those countries with a more recent experience of fertility [...]

Auhtors: Wang N, Tian X, Chen Y, Tan HQ, Xie PJ, Chen SJ, et al. PMID: 29089617 PMCID: PMC5666019 DOI: 10.1038/s41598-017-14408-7 Abstract The aim of this study was to determine whether low dose doxycycline as an anti-inflammatory agent could improve glucose metabolism in diabetic animals. Therefore, doxycycline was supplemented in drinking water to 6-week-old male [...]

Auhtors: Majety M, Runza V, Lehmann C, Hoves S, Ries CH PMID: 28941174 DOI: 10.1111/febs.14277 Abstract Despite decades of research, cancer remains a devastating disease and new treatment options are needed. Today cancer is acknowledged as a multifactorial disease not only comprising of aberrant tumor cells but also the associated stroma including tumor vasculature, fibrotic [...]

Auhtors: Muscaritoli M, Lucia S, Farcomeni A, Lorusso V, Saracino V, Barone C, et al. PMID: 29108370 PMCID: PMC5668103 DOI: 10.18632/oncotarget.20168 Abstract Background: In cancer patients, malnutrition is associated with treatment toxicity, complications, reduced physical functioning, and decreased survival. The Prevalence of Malnutrition in Oncology (PreMiO) study identified malnutrition or its risk among cancer patients [...]

Auhtors: Hoffman K, Lorenzo A, Butt CM, Hammel SC, Henderson BB, Roman SA, et al. PMID: 28772138 DOI: 10.1016/j.envint.2017.06.021 Abstract Background: Thyroid cancer is the fastest increasing cancer in the U.S., and papillary thyroid cancer (PTC) accounts for >80% of incident cases. Increasing exposure to flame retardant chemicals (FRs) has raised concerns about their possible [...]

Auhtors: Sun P, Wang H, He Z, Chen X, Wu Q, Chen W, et al. PMID: 29088814 PMCID: PMC5650369 DOI: 10.18632/oncotarget.20301 Abstract Dietary restriction has been recognized as a healthy and natural therapy for cancer. It is reported that different forms of dietary restriction can promote anti-tumor immunity. However, it is not clear how fasting [...]

Auhtors: Zhu Y, Bu S PMID: 29081818 PMCID: PMC5610853 DOI: 10.1155/2017/5787218 Abstract Objective: Curcumin is an active extract from turmeric. The aim of this study was to identify the underlying mechanism of curcumin on PCa cells and the role of autophagy in this process. Methods: The inhibitory effect of curcumin on the growth of PANC1 [...]

Auhtors: Medema JP PMID: 28854096 DOI: 10.1056/NEJMcibr1706541 Abstract Two recent studies in mice show that, on ablation of colon cancer stem cells, differentiated cancer cells can dedifferentiate to supply a new pool of cancer stem cells, and extracellular signals have a role in this process. Keywords: colorectal cancer, stem cell Source: https://pubmed.ncbi.nlm.nih.gov/28854096/ Archive: https://archive.is/UgkLh [...]

Auhtors: Dehghan M, Mente A, Zhang X, Swaminathan S PMID: 28864332 DOI: 10.1016/S0140-6736(17)32252-3 Abstract Background: The relationship between macronutrients and cardiovascular disease and mortality is controversial. Most available data are from European and North American populations where nutrition excess is more likely, so their applicability to other populations is unclear. Methods: The Prospective Urban Rural [...]

Auhtors: Yuan C, Bao Y, Sato K, Nimptsch K, Song M, Brand-Miller JC, et al. PMID: 28817837 PMCID: PMC5625675 DOI: 10.1038/bjc.2017.272 Abstract Background: Although hyperinsulinemia is hypothesised to be involved in colorectal carcinogenesis, it remains unclear whether a diet inducing an elevated insulin response influences colorectal cancer (CRC) survival. Methods: We examined the association of [...]