Authors: Fadel R, Morrison AR, Vahia A, Smith ZR, Chaudry Z, Bhargava P et al. PMID: 32427279 PMCID: PMC7314133 DOI: 10.1093/cid/ciaa601 Abstract Background: There is no proven antiviral or immunomodulatory therapy for coronavirus disease 2019 (COVID-19). The disease progression associated with the proinflammatory host response prompted us to examine the role of early corticosteroid therapy [...]

Authors: Murai IH, Fernandes AL, Sales LP, Pinto AJ, Goessler KF. doi: https://doi.org/10.1101/2020.11.16.20232397 Abstract Importance Patients with COVID-19 may exhibit 25-hydroxyvitamin D deficiency, but the beneficial effects of vitamin D3 supplementation in this disease remain to be proven by randomized controlled trials. Objective To investigate the efficacy and safety of vitamin D3 supplementation in patients [...]

Authors: Arslan B, Ergun NU, Topuz S, Semerci SY, Suner N. DOI: 10.2139/ssrn.3682517 Abstract Background: While waiting for vaccine, hygiene measures, social distance and personal protective equipment are the only basic protection against Novel Coronavirus. However, these are not sufficient to protect healthcare workers.This study aimed to evaluate if quercetin and vitamin C could be [...]

Auhtors: Kim TL, Jeong GH, Yang JW, Lee KH, Kronbichler A, van der Vliet HJ, et al. PMID: 32667980 PMCID: PMC7666907 DOI: 10.1093/advances/nmaa077 Abstract Tea is one of the most widely consumed beverages, but its association with cancer risk remains controversial and unclear. We performed an umbrella review to clarify and determine the associations between [...]

Authors: Clausen TM, Sandoval DR, Spliid CB, PiHl J, Painter CD, Thacker BE et al. PMID: 32970989 PMCID: PMC7489987 DOI: 10.1016/j.cell.2020.09.033 Abstract We show that SARS-CoV-2 spike protein interacts with both cellular heparan sulfate and angiotensin-converting enzyme 2 (ACE2) through its receptor-binding domain (RBD). Docking studies suggest a heparin/heparan sulfate-binding site adjacent to the ACE2-binding [...]

Authors: Abou-Arab O, Huette P, Debouvries F, Dupont H, Jounieaux V PMID: 33183348 PMCID: PMC7661015 DOI: 10.1186/s13054-020-03371-x Abstract The role of inhaled nitric oxide (iNO) in the management of severe hypoxia due to coronavirus disease 2019 (Covid-19) is a subject of debate. Despite the lack of clinical data, the surviving sepsis campaign recommended the use [...]

Authors: Chopra V, Flanders SA, O'Malley M PMID: 33175566 PMCID: PMC7707210 DOI: 10.7326/M20-5661 Abstract Background: Although characteristics and in-hospital outcomes for persons with coronavirus disease 2019 (COVID-19) have been well described, less is known about the longer-term outcomes of hospitalized patients. Objective: To describe 60-day postdischarge clinical, financial, and mental health outcomes of patients with [...]

Auhtors: Debras C, Chazelas E, Srour B, Kesse-Guyot E, Julia C, Zelek L, et al. PMID: 32936868 DOI: 10.1093/ajcn/nqaa246 Abstract Background: Excessive sugar intake is now recognized as a key risk factor for obesity, type 2 diabetes, and cardiovascular diseases. In contrast, evidence on the sugar-cancer link is less consistent. Experimental data suggest that sugars [...]

Authors: Din AU, Mazhar M, Waseem M, Ahmad w, Bibi A. PMID: 33197765 PMCID: PMC7657099 DOI: 10.1016/j.biopha.2020.110947 Abstract</h5 In December 2019, a pneumonia outbreak of unknown etiology was reported which caused panic in Wuhan city of central China, which was later identified as Coronavirus disease (COVID-19) caused by a novel coronavirus, Severe Acute Respiratory Syndrome [...]

Auhtors: Bischoff-Ferrari HA, Vellas B, Rizzoli R, Kressig RW PMID: 33170239 PMCID: PMC7656284 DOI: 10.1001/jama.2020.16909 Abstract Importance: The benefits of vitamin D, omega-3 fatty acids, and exercise in disease prevention remain unclear. Objective: To test whether vitamin D, omega-3s, and a strength-training exercise program, alone or in combination, improved 6 health outcomes among older adults. [...]