Auhtors: Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ PMID: 18287387 DOI: 10.3322/CA.2007.0010 Abstract Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and [...]

Ivermectin is an antiparasitic drug with a broad spectrum of activity, high efficacy as well as a wide margin of safety. Since 1987, this compound has a widespread use in veterinary medicine and it use has been extended in humans. Here we present a brief review of the information availabile regarding the pharmacokinetics and interactions of ivermectin in humans. Awareness of these characteristics could improve the clinical efficacy of Ivermectin. All Authors declare that they do not have any Conflict of interest and that the work is original. All Authors agree that the contents of the manuscript are confidential and will not be copyrighted, submitted, or published elsewhere (including the Internet), in any language, while acceptance by the Journal is under consideration.

Authors: Lau T, Horschitz S, Berger S, Bartsch D, Schloss P PMID: 18216289 DOI: 10.1096/fj.07-095471 Abstract A deficiency of serotonergic signaling is thought to be involved in the etiology of depression. Thus, drugs blocking the reuptake of serotonin back into the neurons are widely used in treatment of this disease; however, their delayed effect in [...]

Authors: Jacob A, Wu R, Zhou M, Wang P PMID: 18274631 PMCID: PMC2234255 DOI: 10.1155/2007/89369 Abstract Curcumin, the phytochemical component in turmeric, is used as a dietary spice and a topical ointment for the treatment of inflammation in India for centuries. Curcumin (diferuloylmethane) is relatively insoluble in water, but dissolves in acetone, dimethylsulphoxide, and ethanol. [...]

Authors: Blaylock RL doi: 10.1588/medver.2008.05.00183 Abstract There is growing evidence that a number of the psychiatric disorders are strongly related to glutamate excess. Likewise, recent studies have shown a connection between chronic inflammation and these same disorders. A compelling body of research links these two observations, glutamate excess (an excitotoxicity marker) and chronic inflammation (immune [...]

Authors: Shevchuk N PMID: 17993252 DOI: 10.1016/j.mehy.2007.04.052 Abstract Depression is a debilitating mood disorder that is among the top causes of disability worldwide. It can be characterized by a set of somatic, emotional, and behavioral symptoms, one of which is a high risk of suicide. This work presents a hypothesis that depression may be caused [...]

Auhtors: Merhi M, Raynal H, Cahuzac E, Vinson F, Cravedi JP, Gamet-Payrastre L PMID: 17874193 DOI: 10.1007/s10552-007-9061-1 Abstract Objective: In this study we conducted a meta-analysis of 13 case-control studies that examined the occurrence of hematopoietic cancers in pesticide related occupations in order to undertake a qualitative and quantitative evaluation of a possible relationship. Methods: [...]

Auhtors: Holick MF PMID: 17634462 DOI: 10.1056/NEJMra070553 Abstract Once foods in the United States were fortified with vitamin D, rickets appeared to have been conquered, and many considered major health problems from vitamin D deficiency resolved. But vitamin D deficiency is common. This review considers the role of vitamin D in skeletal and nonskeletal health [...]

The objective of this paper is to determine the effect of ivermectin administration on cell mediated (CMI) and humoral immunity (HI) of rabbits.

Auhtors: Zhou W, Mukherjee P, Kiebish MA, Markis WT, Mantis JG, Seyfried TN PMID: 17313687 PMCID: PMC1819381 DOI: 10.1186/1743-7075-4-5 Abstract Background: Malignant brain cancer persists as a major disease of morbidity and mortality in adults and is the second leading cause of cancer death in children. Many current therapies for malignant brain tumors fail to [...]