Authors: de Souza dos Santos MC, Goncalves CF, Vaisman M, Ferreira AC, de Carvalho DP. PMID: 21745527 DOI: 10.1016/j.fct.2011.06.074 Abstract Flavonoids are polyphenolic compounds of natural occurrence produced by plants that are largely consumed both for therapeutic purposes and as food. Experimental data have shown that many flavonoids could inhibit thyroperoxidase activity, decreasing thyroid hormones [...]

Authors: Leuner B, Caponiti JM, Gould E PMID: 21692136 PMCID: PMC4756590 DOI: 10.1002/hipo.20947 Abstract Oxytocin has been linked to social behavior, including social recognition, pair bonding and parenting, but its potential role in promoting neuronal growth has not been investigated. We show here that oxytocin, but not vasopressin, stimulates both cell proliferation and adult neurogenesis [...]

Authors: Lee CY, Jan WC, Tsai PS, Huang CJ PMID: 21610432 DOI: 10.1097/TA.0b013e31820ca695 Abstract Background: Magnesium sulfate (MgSO4) possesses potent anti-inflammation capacity. We sought to elucidate the effects of MgSO4 on mitigating acute lung injury induced by endotoxemia. MgSO4 is an antagonist of the L-type calcium channels and the N-methyl-D-aspartate (NMDA) receptor. The roles of [...]

Authors: Nicolson GL, Settineri R DOI: 10.31989/ffhd.v1i4.134 Abstract Background: Cancer-associated fatigue and the chronic adverse effects of cancer therapy can be reduced by Lipid Replacement Therapy (LRT) using membrane phospholipid mixtures given as food supplements. Methods: This is a review of the published literature on LRT and its uses. Results: LRT significantly reduced fatigue in [...]

Auhtors: Vilchez RA, Madden CR, Kozinetz CA, Halvorson SJ, White ZS, Jorgensen JL, et al. PMID: 15202523 DOI: 10.1080/10428190310001623784 Abstract Millions of people worldwide were inadvertently exposed to live simian virus 40 (SV40) between 1955 and 1963 through immunization with SV40-contaminated polio vaccines. Although the prevalence of SV40 infections in humans is not known, numerous [...]

Auhtors: Mulrooney TJ, Marsh J, Urits I, Seyfried TN, Mukherjee P PMID: 21479220 PMCID: PMC3068150 DOI: 10.1371/journal.pone.0018085 Abstract Background: Many of the current standard therapies employed for the management of primary malignant brain cancers are largely viewed as palliative, ultimately because these conventional strategies have been shown, in many instances, to decrease patient quality of [...]

Auhtors: Hanahan D, Weinberg RA PMID: 21376230 DOI: 10.1016/j.cell.2011.02.013 Abstract The hallmarks of cancer comprise six biological capabilities acquired during the multistep development of human tumors. The hallmarks constitute an organizing principle for rationalizing the complexities of neoplastic disease. They include sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, [...]

Authors: Morselli E, Marino G, Bennetzen MV, Eisenberg T, Megalou E, Schroeder S et al. PMID: 21339330 PMCID: PMC3044119 DOI: 10.1083/jcb.201008167 Abstract Autophagy protects organelles, cells, and organisms against several stress conditions. Induction of autophagy by resveratrol requires the nicotinamide adenine dinucleotide-dependent deacetylase sirtuin 1 (SIRT1). In this paper, we show that the acetylase inhibitor [...]

Authors: Sathyapalan T, Manuchehri AM, Thatcher NJ, Rigby AS, Chapman T. PMID: 21325465 DOI: 10.1210/jc.2010-2255 Abstract Context: There is concern whether soy phytoestrogens may affect thyroid function. If true, soy phytoestrogens may be expected to have a greater impact in subjects with subclinical hypothyroidism. Objective: The primary aim was to determine the effect of soy [...]

Auhtors: Fearon K, Strasser F, Anker SD, Bosaeus I, Bruera E, Fainsinger RL, et al. PMID: 21296615 DOI: 10.1016/S1470-2045(10)70218-7 Abstract To develop a framework for the definition and classification of cancer cachexia a panel of experts participated in a formal consensus process, including focus groups and two Delphi rounds. Cancer cachexia was defined as a [...]