Auhtors: Patra KC, Hay N PMID: 24196563 PMCID: PMC3875752 DOI: 10.18632/oncotarget.1563 Abstract It is well established that cancer cells differ from most somatic adult cells by their high rate of aerobic glycolysis despite oxidative phosphorylation. This distinct property of cancer cells is often used for tumor imaging in vivo following the administration of the labeled [...]

Authors: Houghton CA, Fassett RG, Coombes JS PMID: 24147970 DOI: 10.1111/nure.12060 Abstract Cruciferous vegetables are widely acknowledged to provide chemopreventive benefits in humans, but they are not generally consumed at levels that effect significant change in biomarkers of health. Because consumers have embraced the notion that dietary supplements may prevent disease, this review considers whether [...]

Auhtors: Newman JC, Verdin E PMID: 24140022 PMCID: PMC4176946 DOI: 10.1016/j.tem.2013.09.002 Abstract Traditionally, the ketone body β-hydroxybutyrate (βOHB) has been looked upon as a carrier of energy from liver to peripheral tissues during fasting or exercise. However, βOHB also signals via extracellular receptors and acts as an endogenous inhibitor of histone deacetylases (HDACs). These recent [...]

Authors: Ray K PMID: 23982685 DOI: 10.1038/nrgastro.2013.170 Abstract Coffee drinking is a global phenomenon, with an estimated >2.25 billion cups of coffee consumed in the world every day. A myriad of health benefits across a wide range of diseases have been attributed to coffee consumption and much research has focussed on the effects of caffeine [...]

Authors:Bergman P, Lindh AU, Bjorkhem-Bergman L, Lindhagen L. PMID:PMC3686844 DOI: 10.1371/journal.pone.0065835 Abstract Background: Low levels of 25-OH vitamin D are associated with respiratory tract infection (RTI). However, results from randomized controlled trials are inconclusive. Therefore, we performed a systematic review and meta-analysis to assess the preventive effect of vitamin D supplementation [...]

Auhtors: Wang S-F, Hu W-W, Yan H-J, Tan L, Gao J-Q, Tian Y-Y, et al. PMID: 23791924 DOI: 10.1016/j.neulet.2013.06.013 Abstract Histamine, a neurotransmitter or neuromodulator has been demonstrated to be neuroprotective in cerebral ischemia. However, few reports concern its function on astrocytes during cerebral ischemia. The purpose of this study was to investigate the effects [...]

Auhtors: Shin S, Jing K, Jeong S, Kim N, Song K-S, Heo J-Y, et al. PMID: 23841076 PMCID: PMC3691929 DOI: 10.1155/2013/568671 Abstract Docosahexaenoic acid (DHA) induces autophagy-associated apoptotic cell death in wild-type p53 cancer cells via regulation of p53. The present study investigated the effects of DHA on PC3 and DU145 prostate cancer cell lines [...]

Authors: Ranjbar E, Kasaei MS, Mohammad-Shirazi M, Shams J, Mostafavi SA PMID: 24130605 PMCID: PMC3796297 Abstract Objective: Major depression is a mood disorder that causes changes in physical activity, appetite, sleep and weight. Regarding the role of zinc in the pathology of depression, the present study was aimed to investigate the effects of zinc supplementation [...]

Authors: Kessler NJ, Hong J PMID: 24139013 DOI: 10.1016/j.jbmt.2013.03.001 Abstract The unsatisfactory results associated with conventional treatments for symptoms of diabetic peripheral neuropathy (DPN) demonstrate a need for research into alternative therapies. The purpose of this study was to determine the efficacy of whole body vibration therapy (WBV) as a treatment for pain associated with [...]

Authors: LaRocca TJ, Gioscia-Ryan RA, Hearon CM, Seals DR PMID: 23612189 PMCID: PMC3700669 DOI: 10.1016/j.mad.2013.04.004 Abstract Arterial aging, characterized by stiffening of large elastic arteries and the development of arterial endothelial dysfunction, increases cardiovascular disease (CVD) risk. We tested the hypothesis that spermidine, a nutrient associated with the anti-aging process autophagy, [...]