Auhtors: Cao X, Li Y, Wang Y, Yu T, Zhu C, Zhang X, Guan J PMID: 35041678 PMCID: PMC8765616 DOI: 10.1371/journal.pone.0261370 Abstract Breast cancer (BC) is one of the most common malignant tumors found in females. Previous studies have demonstrated that curcumin, which is a type of polyphenol compound extracted from Curcuma longa underground rhizome, [...]

Auhtors: Noman MZ, Desantis G, Janji B, Hasmim M, Karray S, Dessen P, et al. PMID: 35053426 PMCID: PMC8774531 DOI: 10.3390/cells11020310 Abstract Myeloid-derived suppressor cells (MDSCs) are one of the main suppressive cell population of the immune system. They play a pivotal role in the establishment of the tumor microenvironment (TME). In the context of [...]

Auhtors: Ma T, Renz BW, Ilmer M, Koch D, Yang Y, Werner J, Bazhin AV PMID: 35053426 PMCID: PMC8774531 DOI: 10.3390/cells11020310 Abstract Myeloid-derived suppressor cells (MDSCs) are one of the main suppressive cell population of the immune system. They play a pivotal role in the establishment of the tumor microenvironment (TME). In the context of [...]

Authors: Gutierrez-Castrellon P, Gandara-Marti T, Abreu AT, Nieto-Rufino CD, Lopez-Orduna E PMID: 35014600 PMCID: PMC8757475 DOI: 10.1080/19490976.2021.2018899 Abstract Intestinal bacteria may influence lung homeostasis via the gut-lung axis. We conducted a single-center, quadruple-blinded, randomized trial in adult symptomatic Coronavirus Disease 2019 (Covid19) outpatients. Subjects were allocated 1:1 to probiotic formula (strains Lactiplantibacillus plantarum KABP022, KABP023, [...]

Authors: Izquierdo JL, Soriano JB, Gonzalez Y, Lumbreras S PMID: 35084258 PMCID: PMC8795755 DOI: 10.1177/00368504221074574 Abstract Infection by SARS-CoV-2 causing coronavirus disease 2019 (COVID-19) can be associated with serious and life-threatening conditions, including acute respiratory distress syndrome (ARDS). Severity and mortality have been related to a cytokine storm, an imbalance of oxidative stress, and a [...]

Authors: Patterson BK, Francisco EB, Yogendra R, Long E, Pise A, Hall E et al. PMID: 35082777 PMCID: PMC8784688 DOI: 10.3389/fimmu.2021.746021 AbstractThe recent COVID-19 pandemic is a treatment challenge in the acute infection stage but the recognition of chronic COVID-19 symptoms termed post-acute sequelae SARS-CoV-2 infection (PASC) may affect up to 30% of all infected [...]

Authors: Rondanelli M, Perna S, Gasparri C, Petrangolini G, Cavioni A, Peroni G. PMID: 35054459 PMCID: PMC8780248 DOI: 10.3390/life12010066 Abstract Quercetin, for its crucial properties, fulfills the need for a multifactor action that is useful for the potential counterbalance of a COVID-19 infection. Given this background, the aim of the study was to evaluate the [...]

Authors: Santamarina MG, Beddings I, Martinez Lomakin F, Boisier Riscal D PMID: 34980198 PMCID: PMC8721481 DOI: 10.1186/s13054-021-03885-y Abstract Background: SARS-CoV-2 seems to affect the regulation of pulmonary perfusion. Hypoperfusion in areas of well-aerated lung parenchyma results in a ventilation-perfusion mismatch that can be characterized using subtraction computed tomography angiography (sCTA). This study aims to evaluate [...]

Authors: Clemency BM, Varughese R, Morse CG, Koster DJ, Blaiss MS PMID: 34807241 PMCID: PMC8609464 DOI: 10.1001/jamainternmed.2021.6759 Abstract Importance: Systemic corticosteroids are commonly used in treating severe COVID-19. However, the role of inhaled corticosteroids in the treatment of patients with mild to moderate disease is less clear. Objective: To determine the efficacy of the inhaled [...]

Authors: Pretorius E, Venter C, Laubshder G, Kotze M, Moremi K doi: https://doi.org/10.21203/rs.3.rs-1205453/v1 Abstract We recognise that fibrin(ogen) amyloid microclots and platelet hyperactivation, that we have previously observed in COVID-19 and Long COVID/Post-Acute Sequelae of COVID-19 (PASC) patients, might form a suitable set of foci for the clinical treatment of the symptoms of long COVID/PASC. [...]