Auhtors: Li J, Fan Y, Zhang Y, Liu Y, Yu Y, Ma M PMID: 35745143 PMCID: PMC9228598 DOI: 10.3390/nu14122413 Abstract Resveratrol (RSV) has been reported to induce autophagy and apoptosis in non-small-cell lung cancer A549 cells, and the nerve growth factor receptor (NGFR) regulates autophagy and apoptosis in many other cells. However, the effect of [...]

Auhtors: Ferraresi A, Esposito A, Girone C, Vallino L, Salwa A, Ghezzi I, et al. PMID: 34831435 PMCID: PMC8625920 DOI: 10.3390/cells10113213 Abstract Background: Ovarian cancer progression and invasiveness are promoted by a range of soluble factors released by cancer cells and stromal cells within the tumor microenvironment. Our previous studies demonstrated that resveratrol (RV), a [...]

Auhtors: Tian Y, Song W, Li D, Cai L, Zhao Y PMID: 31802896 PMCID: PMC6802539 DOI: 10.2147/OTT.S213043 Abstract Resveratrol, as a natural product compound, has been recently attracted much attention for its potent effects on cancer. Cancer is a serious disease threatening human survival and social development. Autophagy is a cellular pathway to realize the [...]

Auhtors: Liu Z, Peng Q, Li Y, Gao Y PMID: 30103844 PMCID: PMC6177506 DOI: 10.5483/BMBRep.2018.51.9.114 Abstract Cisplatin is one of the most effective chemotherapeutic drugs used in the treatment of HCC, but many patients will ultimately relapse with cisplatin-resistant disease. Used in combination with cisplatin, resveratrol has synergistic effect of increasing chemosensitivity of cisplatin in [...]

Auhtors: Ko JH, Sethi G, Um JY, Shanmugam MK, Arfuso F, Kumar AP, et al. PMID: 29194365 PMCID: PMC5751192 DOI: 10.3390/ijms18122589 Abstract Abstract: Natural product compounds have recently attracted significant attention from the scientific community for their potent effects against inflammation-driven diseases, including cancer. A significant amount of research, including preclinical, clinical, and epidemiological studies, [...]

Authors: Kou X, Chen N PMID: 28837083 PMCID: PMC5622687 DOI: 10.3390/nu9090927 Abstract Alzheimer's disease (AD) is one of the most common neurodegenerative disorders over the age of 65 years old. Although several underlying mechanisms for explaining the pathogenesis of AD are elucidated, the effective supplements or drugs for the intervention of AD are still limited. [...]

Auhtors: León D, Uribe E, Zambrano A, Salas M PMID: 28272357 PMCID: PMC6155386 DOI: 10.3390/molecules22030398 Abstract Resveratrol-a polyphenol of natural origin-has been the object of massive research in the past decade because of its potential use in cancer therapy. However, resveratrol has shown an extensive range of cellular targets and effects, which hinders the use [...]

Authors: Park D, Jeong H, Lee MN, Koh A, Kwon O, Yang YR et al. PMID: 26902888 PMCID: PMC4763238 DOI: 10.1038/srep21772 Abstract Resveratrol (RSV) is a natural polyphenol that has a beneficial effect on health, and resveratrol-induced autophagy has been suggested to be a key process in mediating many beneficial effects of resveratrol, such as [...]

Authors: Morselli E, Marino G, Bennetzen MV, Eisenberg T, Megalou E, Schroeder S et al. PMID: 21339330 PMCID: PMC3044119 DOI: 10.1083/jcb.201008167 Abstract Autophagy protects organelles, cells, and organisms against several stress conditions. Induction of autophagy by resveratrol requires the nicotinamide adenine dinucleotide-dependent deacetylase sirtuin 1 (SIRT1). In this paper, we show that the acetylase inhibitor [...]

Authors: Walle T PMID: 21261636 DOI: 10.1111/j.1749-6632.2010.05842.x Abstract This paper reviews our current understanding of the absorption, bioavailability, and metabolism of resveratrol, with an emphasis on humans. The oral absorption of resveratrol in humans is about 75% and is thought to occur mainly by transepithelial diffusion. Extensive metabolism in the intestine and liver results in [...]