Authors: Bek LM, Berentschot JC, Huijts S, Vlake JH, Aerts JG PMID: 36284829 PMCID: PMC9421428 DOI: 10.1183/23120541.00355-2022 Abstract Introduction: A large proportion of patients experience a wide range of sequelae after acute COVID-19, especially after severe illness. The long-term health sequelae need to be assessed. Our objective was to longitudinally assess [...]

Authors: Peluso MJ, Deveau TM, Munter SE, Ryder D, Buck A, Lu S et al. doi: https://doi.org/10.1101/2022.06.21.22276660 Abstract Epstein-Barr virus (EBV) reactivation has been proposed as a driver of Long COVID (LC), but studies in well- characterized post-acute COVID-19 cohorts of individuals with and without Long COVID symptoms over a time course consistent with current [...]

Authors: Voruz P, Allali G, Benzakour L, Jacot I, Pierce J doi: https://doi.org/10.3390/ctn6020009 Abstract There is growing awareness that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, even in its mild or moderate respiratory forms, can include long-term neuropsychological deficits. Standardized neuropsychological, psychiatric, neurological, and olfactory tests were administered to 45 patients 236.51 ± 22.54 [...]

Authors: Oaklander AL, Mills AJ, Kelley M, Toran MK PMID: 35232750 PMCID: PMC8889896 DOI: 10.1212/NXI.0000000000001146 Abstract Background and objectives: Recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection appears exponential, leaving a tail of patients reporting various long COVID symptoms including unexplained fatigue/exertional intolerance and dysautonomic and sensory concerns. Indirect evidence links long COVID [...]

Authors: Patterson B, Yogendra R, Guevara-Coto J, Osgood E, Bream J, Parikh P DOI:10.21203/rs.3.rs-1344323/v1 Abstract Post-acute sequelae of COVID (PASC), or long COVID, is a multisystem complication of SARS-CoV-2 infection that continues to debilitate millions worldwide thus highlighting the public health importance of identifying effective therapeutics to alleviate this illness. The [...]

Authors: Pretorius E, Venter C, Laubshder G, Kotze M, Moremi K doi: https://doi.org/10.21203/rs.3.rs-1205453/v1 Abstract We recognise that fibrin(ogen) amyloid microclots and platelet hyperactivation, that we have previously observed in COVID-19 and Long COVID/Post-Acute Sequelae of COVID-19 (PASC) patients, might form a suitable set of foci for the clinical treatment of the symptoms of long COVID/PASC. [...]

Authors: Sabel BA, Zhou W, Huber F, Schmidt F, Sabel K PMID: 34924406 PMCID: PMC8764598 DOI: 10.3233/RNN-211249 Abstract Background: An effective treatment is needed for long-COVID patients which suffer from symptoms of vision and/or cognition impairment such as impaired attention, memory, language comprehension, or fatigue. Objective: Because COVID-19infection causes reduced blood flow which may cause [...]

Authors: Robbins T, Gonevski M, Clark C, Sharma K, Magar A PMID: 34862223 PMCID: PMC8806311 DOI: 10.7861/clinmed.2021-0462 Abstract Background: Long COVID is a common occurrence following COVID-19 infection. The most common symptom reported is fatigue. Limited interventional treatment options exist. We report the first evaluation of hyperbaric oxygen therapy (HBOT) for long COVID treatment. Methods: [...]

Authors: Weinstock LB, Brook JB, Walters AS, Goris A, Afrin LB, Molderings GJ PMID: 34563706 PMCID: PMC8459548 DOI: 10.1016/j.ijid.2021.09.043 Abstract Objectives: Hyper-inflammation caused by COVID-19 may be mediated by mast cell activation (MCA) which has also been hypothesized to cause Long-COVID (LC) symptoms. We determined prevalence/severity of MCA symptoms in LC. Methods: Adults in LC-focused [...]

Authors:Michelen M, Manoharan L, Elkheir N, Cheng V, Dagens D, Hastie C. . PMID: PMC8478580 DOI: 10.1136/bmjgh-2021-005427 Abstract Background: While it is now apparent clinical sequelae (long COVID) may persist after acute COVID-19, their nature, frequency and aetiology are poorly characterised. This study aims to regularly synthesise evidence on long COVID characteristics, to help inform [...]