Auhtors: Cao X, Li Y, Wang Y, Yu T, Zhu C, Zhang X, Guan J PMID: 35041678 PMCID: PMC8765616 DOI: 10.1371/journal.pone.0261370 Abstract Breast cancer (BC) is one of the most common malignant tumors found in females. Previous studies have demonstrated that curcumin, which is a type of polyphenol compound extracted from Curcuma longa underground rhizome, [...]

Authors: Ahmadi R, Salari S, Reihani H, Eslami S. PMID: PMC8358331 DOI: 10.1002/fsn3.2226 Abstract Background: Curcumin, a natural polyphenolic compound, is proposed as a potential treatment option for patients with coronavirus disease by inhibiting the entry of virus to the cell, encapsulation of the virus and viral protease, as well as modulating various cellular signaling [...]

Auhtors: Marton LT, Pescinini-e-Salzedas LM, Eduarda M, Camargo C, Barbalho SM, dos Santos Haber JF, et al. PMID: 34012421 PMCID: PMC8126655 DOI: 10.3389/fendo.2021.669448 Abstract Diabetes mellitus (DM) is an ensemble of metabolic conditions that have reached pandemic proportions worldwide. Pathology's multifactorial nature makes patient management, including lifelong drug therapy and lifestyle modification, extremely challenging. Currently, [...]

Authors: Valizadeh H, Danshina S, Gencer MZ, Ammari A, Sadeghi A, Aslani S. PMID: PMC7574843 DOI: 10.1016/j.intimp.2020.107088 Abstract Background: As an ongoing worldwide health issue, Coronavirus disease 2019 (COVID-19) has been causing serious complications, including pneumonia, acute respiratory distress syndrome (ARDS), and multi-organ failure. However, there is no decisive treatment approach available for this disorder, [...]

Auhtors: Rainey NE, Moustapha A, Petit PX PMID: 32765806 PMCID: PMC7387956 DOI: 10.1155/2020/3656419 Abstract Curcumin has extensive therapeutic potential because of its antioxidant, anti-inflammatory, and antiproliferative properties. Multiple preclinical studies in vitro and in vivo have proven curcumin to be effective against various cancers. These potent effects are driven by curcumin's ability to induce G2/M [...]

Authors: Moballegh Nasery M, Abadi B, Poormoghadam D, Zarrabi A, Keyhanvar P, Tavakol S et al. PMID: PMC7037405 DOI: 10.3390/molecules25030689 Abstract Todays, nano-pharmaceutics is emerging as an important field of science to develop and improve efficacy of different drugs. Although nutraceuticals are currently being utilized in the prevention and treatment of various chronic diseases such [...]

Auhtors: Sala De Oyanguren FJ, Rainey NE, Moustapha A, Saric A, Sureau F, O’Connor J-E, Petit PX PMID: 32033136 PMCID: PMC7072416 DOI: 10.3390/cells9020361 Abstract Curcumin, a major active component of turmeric (Curcuma longa, L.), is known to have various effects on both healthy and cancerous tissues. In vitro studies suggest that curcumin inhibits cancer cell [...]

Authors: Chai YS, Chen YQ, Lin SH, Xie K, Wang CJ, Yang YZ. PMID: 32004976 DOI: 10.1016/j.biopha.2020.109946 Abstract Objectives: Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is one type of respiratory failure characterized by rapid onset of widespread inflammation in the lungs. Curcumin has been reported to be an anti-inflammatory factor through enhancing the function [...]

Authors: Kunnumakkara AB, Harsha C, Banik K, Vikkurthi R, Sailo BL, Bordoloi D PMID: 31361978 DOI: 10.1080/17425255.2019.1650914 Abstract Introduction: Since ancient times, turmeric has been used in several folklore remedies against various ailments. The principal component of turmeric is curcumin and its efficacy has been advocated in various in vitro, in vivo and clinical studies [...]

Authors: Keihanian F, Saeidinia A, Bagheri RK, Johnston TP, Sahebkar A PMID: 29052850 DOI: 10.1002/jcp.26249 Abstract Atherothrombotic cardiovascular disease is a major cause of mortality throughout the world. Platelet activation and aggregation play a central role in hemostasis and thrombosis. Herbal medicines have been traditionally used in the management of cardiovascular disease and can help [...]