Authors: Li L, Zhang W, Hu Y, Tong X, Zeng S, Yang J PMID: 32492084 PMCID: PMC7270883 DOI: 10.1001/jama.2020.10044 Abstract Importance: Convalescent plasma is a potential therapeutic option for patients with coronavirus disease 2019 (COVID-19), but further data from randomized clinical trials are needed. Objective: To evaluate the efficacy and adverse effects of convalescent plasma [...]

Authors: Morath C, Weigand MA, Zeier M, Speer C, Tiwari-Heckler S PMID: 32753056 PMCID: PMC7399583 DOI: 10.1186/s13054-020-03171-3 Abstract The spectrum of coronavirus disease 2019 (COVID-19) ranges from asymptomatic infection to respiratory failure and death of patients. Severely affected patients may develop a cytokine storm-like clinical syndrome with multi-organ failure and a mortality rate of up [...]

Authors: Tobin MJ, Laghi F, Jubran A PMID: 32539537 PMCID: PMC7397783 DOI: 10.1164/rccm.202006-2157CP Abstract Patients with coronavirus disease (COVID-19) are described as exhibiting oxygen levels incompatible with life without dyspnea. The pairing-dubbed happy hypoxia but more precisely termed silent hypoxemia-is especially bewildering to physicians and is considered as defying basic biology. This combination has attracted [...]

Authors: Hiedra R, Lo KB, Elbashabsheh M, Gul F, Wright RM PMID: 32662690 PMCID: PMC7441798 DOI: 10.1080/14787210.2020.1794819 Abstract Background: The coronavirus disease 2019 (COVID-19) pandemic has affected almost 2.5 million people worldwide with almost 170,000 deaths reported to date. So far, there is scarce evidence for the current treatment options available for COVID-19. Vitamin C [...]

Authors: Qin C, Zhou L, Hu Z, Zhang S PMID: 32161940 PMCID: PMC7108125 DOI: 10.1093/cid/ciaa248 Abstract Background: In December 2019, coronavirus 2019 (COVID-19) emerged in Wuhan and rapidly spread throughout China. Methods: Demographic and clinical data of all confirmed cases with COVID-19 on admission at Tongji Hospital from 10 January to 12 February 2020 were [...]

Authors: Kwon PS, Oh H, Kwon SJ, Jin W, Zhang F, Fraser K et al. PMID: 32714563 PMCID: PMC7378085 DOI: 10.1038/s41421-020-00192-8 Abstract COVID-19, caused by the SARS-CoV-2 virus, has now spread worldwide with catastrophic human and economic impacts and currently has infected over 10 million people and killed over 500,0001. In an effort to mitigate [...]

Paul S Kwon, Hanseul Oh, Seok-Joon Kwon, Weihua Jin, Fuming Zhang, Keith Fraser, Jung Joo Hong, Robert J Linhardt, Jonathan S Dordick PMID: 32714563 PMCID: PMC7378085 DOI: 10.1038/s41421-020-00192-8 Abstract No abstract available Keywords:Glycobiology; Mechanisms of disease. Source: https://pubmed.ncbi.nlm.nih.gov/32714563/ Archive: https://archive.is/wip/eUJkR

Authors: Akbar AN, Gilroy DW PMID: 32675364 DOI: 10.1126/science.abb0762 Abstract Aging is associated with increased morbidity arising from a range of tissue dysfunctions. A common denominator of age-associated frailty is increased baseline inflammation, called inflammaging, that is present in older individuals. Recent studies have shown that the presence of excessive inflammation can inhibit immunity in [...]

Authors: Zhang J, Meng G, Li W, Shi B, Dong H, Su Z PMID: 32664991 PMCID: PMC7359422 DOI: 10.1186/s12931-020-01440-x Abstract Background: In December 2019, the outbreak of a disease subsequently termed COVID-19 occurred in Wuhan, China. The number of cases increased rapidly and spread to six continents. However, there is limited information on the chest [...]

Authors: Chowdhury AT, Shahabz M, Karim MR, Islam J, Guo D, He D. DOI: https://doi.org/10.21203/rs.3.rs-38896/v1 Abstract Background The worldwide COVID-19 pandemic was caused by a newly discovered Coronavirus. The treatment methods for COVID-19 are emerging and rapidly evolving. Existing drugs, including Ivermectin and Hydroxychloroquine, offer the hope of effective treatment in early disease. In this [...]