Authors: Sorokowaka A, Drechsler E, Karwowski M, Hummel T PMID: 28040824 DOI: 10.4193/Rhino16.195 Abstract The neural plasticity of the olfactory system offers possibilities of treatment in terms of stimulation of the sense of smell, and different studies have suggested effectiveness of smell training, i.e., daily exposition to certain odors. To obtain reliable and precise estimates [...]

Authors: Rosa DD, Dias MM, Grzeskowiak LM, Reis SA. PMID: 28222814 DOI: 10.1017/S0954422416000275 Abstract Kefir is fermented milk produced from grains that comprise a specific and complex mixture of bacteria and yeasts that live in a symbiotic association. The nutritional composition of kefir varies according to the milk composition, the microbiological composition of the grains [...]

Authors: Kniotek M, Boguska A PMID: 28316997 PMCID: PMC5337856 DOI: 10.1155/2017/4541958 Abstract Sildenafil, a type 5 phosphodiesterase inhibitor (PDE5-I), is primarily used for treating erectile dysfunction. Sildenafil inhibits the degradation of cyclic guanosine monophosphate (cGMP) by competing with cGMP for binding site of PDE5. cGMP is a secondary messenger activating protein kinases and a common [...]

Authors: Rich GT. PMID: 28165426 doi: 10.3390/nu9020111 PMCID: PMC5331542 Abstract We have studied the uptake of quercetin aglycone into CaCo-2/TC7 cells in the presence and absence of mixed micelles that are present in the human small intestine. The micelles inhibited the transport of quercetin into the cells. To gain an understanding of why this is [...]

Authors: Nichols AJ, Hughs OB, Canazza A, Zaiac M PMID: 28367262 PMCID: PMC5367873 Abstract Objective: To evaluate the effectiveness of a novel oral supplement, Forti5®, containing green tea extract, omega 3 and 6 fatty acids, cholecalciferol, melatonin, beta-sitosterol, and soy isoflavones, and in the management of subjects with androgenetic alopecia. Design: A prospective case series [...]

Authors: Larsson P, Alwis I, Niego B, Glise L, Daglas M, Jackson SP PMID: 27706906 DOI: 10.1111/jth.13527 Abstract Essentials Stimulating endogenous fibrinolysis could be a novel antithrombotic strategy. The effect of valproic acid on endothelial tissue plasminogen activator in mice was investigated. Valproic acid increased tissue plasminogen activator expression in vascular endothelium. Valproic acid reduced [...]

Authors: Fung J, Moore J Abstract Thousands of books have been written about the latest and greatest diets that will help people lose weight and improve health. But a key element in any successful nutritional health program is a tried-and-true method that most people haven’t thought about—yet it could be revolutionary for taking health to [...]

Authors: Kim JK, Park SU PMID: 28096787 PMCID: PMC522573 doi: 10.17179/excli2016-485 Abstract Sulforaphane [SFN: 1-isothiocyanato-4-(methylsulfinyl)butane] belongs to the isothiocyanate class of phytochemicals. Glucoraphanin, a glucosinolate precursor of SFN, is a glucosinolate found in cruciferous vegetables such as broccoli, cabbage, cauliflower, and kale. All glucosinolates are composed of a basic structure consisting of a β-D-thioglucose group, [...]

Authors: Ornaghi S, Davis JN, Gorres KL, Miller G, Paidas MJ PMID: 27657833 PMCID: PMC5102808 DOI: 10.1016/j.virol.2016.09.012 Abstract Cytomegalovirus (CMV) infection can generate debilitating disease in immunocompromised individuals and neonates. It is also the most common infectious cause of congenital birth defects in infected fetuses. Available anti-CMV drugs are partially effective but are limited by [...]

Authors: Rahimi HR, Nedaeinia R, Shamloo AS, Nikdoust S. PMID: 27516979 PMCID: PMC4967834 Abstract Objective: Curcumin is extracted from Curcuma longa and regulates the intracellular signal pathways which control the growth of cancerous cell, inflammation, invasion and apoptosis. Curcumin molecules have special intrinsic features that can target the intracellular enzymes, genome (DNA) and messengers (RNA). [...]