Authors:Carvallo H, Hirsch RR, Alkis P, Contreras V. DOI:10.31546/2633-8653.1007 Abstract The severe acute respiratory syndrome-coronavirus-2 pandemic has had devastating health and socio-economic implications worldwide. Epidemiologic data indicate that SARS-CoV2 is spread by respiratory droplets and contact. The lack of acquired human immunity to the virus and the absence of a vaccine, has meant that current [...]

Authors: Al-Hatamleh MA, Hatmal MM, Sattat K, Ahmad S, Mustafa MZ. PMID: PMC7672575 doi: 10.3390/molecules25215017 Abstract The new coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has recently put the world under stress, resulting in a global pandemic. Currently, there are no approved treatments or vaccines, and this severe respiratory illness has [...]

Authors:Green A, Roberts G, Tobery T, Vincent C, Barili M. doi: https://doi.org/10.1101/2020.10.28.359257 Abstract Background saliva is established to contain high counts SARS-CoV-2 virus and contact with saliva droplets, contaminated surfaces or airborne particles are sources of viral transmission. The generation of infective aerosols during clinical procedures is of particular concern. Therefore, a fuller understanding of [...]

Authors: Valizadeh H, Danshina S, Gencer MZ, Ammari A, Sadeghi A, Aslani S. PMID: PMC7574843 DOI: 10.1016/j.intimp.2020.107088 Abstract Background: As an ongoing worldwide health issue, Coronavirus disease 2019 (COVID-19) has been causing serious complications, including pneumonia, acute respiratory distress syndrome (ARDS), and multi-organ failure. However, there is no decisive treatment approach available for this disorder, [...]

Authors:Annweiler C, Hanotte B, de L'Eprevier CG, Sabatier JM, Lafaie L. PMID:PMC7553119 doi: 10.1016/j.jsbmb.2020.105771 Abstract Vitamin D may be a central biological determinant of COVID-19 outcomes. The objective of this quasi-experimental study was to determine whether bolus vitamin D3 supplementation taken during or just before COVID-19 was effective in improving survival among frail elderly nursing-home [...]

Authors: Islam MN, Hossain KS, Sarker PP, Ferdous J, Hannan A, Rahman M. PMID: PMC7675410 DOI: 10.1002/ptr.6895 Abstract Nigella sativa seed and its active compounds have been historically recognized as an effective herbal panacea that can establish a balanced inflammatory response by suppressing chronic inflammation and promoting healthy immune response. The essential oil and other [...]

Authors: Derosa G, Maffioli P, D'Angelo A, Di Pierro F. doi: https://doi.org/10.1002/ptr.6887 Abstract Several months ago, an outbreak of pneumonia of unknown aetiology was detected in Wuhan City (China) and the aetiological agent of the atypical pneumonia was isolated by the Chinese authorities as novel coronavirus (2019-nCoV or SARS-CoV-2). The WHO announced this new disease [...]

Authors: Moozhipurath RK, Kraft L, Skiera B. PMID: PMC7572372 DOI: 10.1038/s41598-020-74825-z Abstract Prior studies indicate the protective role of Ultraviolet-B (UVB) radiation in human health, mediated by vitamin D synthesis. In this observational study, we empirically outline a negative association of UVB radiation as measured by ultraviolet index (UVI) with the number of COVID-19 deaths. [...]

Reports suggest a role of endothelial dysfunction and loss of endothelial barrier function in COVID-19. It is well established that the endothelial glycocalyx-degrading enzyme heparanase contributes to vascular leakage and inflammation.

Authors:Kaufman HW, Niles JK, Kroll MH, Bi C, Holick MF. PMID: PMC7498100 DOI: 10.1371/journal.pone.0239252 Abstract Until treatment and vaccine for coronavirus disease-2019 (COVID-19) becomes widely available, other methods of reducing infection rates should be explored. This study used a retrospective, observational analysis of deidentified tests performed at a national clinical laboratory [...]