Safety and pharmacokinetics (PK) of the antiparasitic drug ivermectin, administered in higher and/or more frequent doses than currently approved for human use, were evaluated in a double-blind, placebo-controlled, dose escalation study.

Authors: Shiraishi T, Nakagawa Y. PMID: 12011519 DOI: 10.1159/000057723 AbstractObjective: Encouragement of gargling is important for the control of opportunistic and community-acquired infections. In hospitals, a povidone-iodine (PVP-I) gargle is used frequently. However, at pharmacies in the community a variety of gargles containing various ingredients are now available. In view of this, we conducted a [...]

Authors: Ader AW, Paul TL, Reinhardt W, Safran M, Pino S, McArthur W et al. PMID: 3350910 DOI: 10.1210/jcem-66-3-632 Abstract A prospective study was conducted to investigate the effect of long term therapy with two iodine-containing mouth rinses on thyroid function. Two groups of subjects were treated daily for 6 months with either a 5% [...]