Auhtors: Choi YS, Cho HJ, Jung HJ PMID: 36039737 PMCID: PMC9437372 DOI: 10.4196/kjpp.2022.26.5.367 Abstract Gastric cancer stem cells (GCSCs) are a major cause of radioresistance and chemoresistance in gastric cancer (GC). Therefore, targeting GCSCs is regarded as a powerful strategy for the effective treatment of GC. Atorvastatin is a widely prescribed cholesterol-lowering drug that inhibits [...]

Auhtors: Akhgarjand C, Asoudeh F, Bagheri A, Kalantar Z, Vahabi Z, Shab-Bidar S, et al. PMID: 36017529 DOI: 10.1002/ptr.7598 Abstract Clinical trial studies revealed conflicting results on the effect of Ashwagandha extract on anxiety and stress. Therefore, we aimed to evaluate the effect of Ashwagandha supplementation on anxiety as well as stress. A systematic search [...]

Auhtors: Evangeliou AE, Spilioti MG, Vassilakou D, Goutsaridou F, Seyfried TN PMID: 36059366 PMCID: PMC9435310 DOI: 10.7759/cureus.27603 Abstract A high-fat and low-carbohydrate diet was administered as a complementary and alternative therapy to a 54-year-old man suffering from non-small-cell lung cancer (NSCLC) with brain metastasis. Three months after the cessation of chemotherapy and radiotherapy, a ketogenic [...]

Auhtors: Wimalawansa SJ PMID: 35889955 PMCID: PMC9319502 DOI: 10.3390/nu14142997 Abstract Vitamin D deficiency is a global public health problem, a pandemic that commonly affects the elderly and those with comorbidities such as obesity, diabetes, hypertension, respiratory disorders, recurrent infections, immune deficiency, and malignancies, as well as ethnic minorities living in temperate countries. The same groups [...]

Auhtors: Sadrekarimi H, Gardanova ZR, Bakhshesh M, Ebrahimzadeh F, Yaseri AF, Thangavelu L, et al. PMID: 35794566 PMCID: PMC9258144 DOI: 10.1186/s12967-022-03492-7 Abstract In recent years, there has been a greater emphasis on the impact of microbial populations inhabiting the gastrointestinal tract on human health and disease. According to the involvement of microbiota in modulating physiological [...]

Auhtors: Rawat SG, Tiwari RK, Jaiswara PK, Gupta VK, Sonker P, Vishvakarma NK, et al. PMID: 35725975 DOI: 10.1007/s10495-022-01741-0 Abstract Cyclic nucleotide phosphodiesterase 5 (PDE5) has been recently identified to play a crucial role in the progression of many cancers. PDE5 promotes tumorigenesis by dysregulating various cellular processes such as proliferation, apoptosis, angiogenesis, and invasion [...]

Auhtors: Goubran H, Stakiw J, Seghatchian J, Ragab G, Burnouf T PMID: 35753906 PMCID: PMC9192107 DOI: 10.1016/j.transci.2022.103488 Abstract The COVID-19 pandemic caused by the SARS-CoV-2 virus has significantly disrupted and burdened the diagnostic workup and delivery of care, including transfusion, to cancer patients across the globe. Furthermore, cancer patients suffering from solid tumors or hematologic [...]

Auhtors: Li J, Fan Y, Zhang Y, Liu Y, Yu Y, Ma M PMID: 35745143 PMCID: PMC9228598 DOI: 10.3390/nu14122413 Abstract Resveratrol (RSV) has been reported to induce autophagy and apoptosis in non-small-cell lung cancer A549 cells, and the nerve growth factor receptor (NGFR) regulates autophagy and apoptosis in many other cells. However, the effect of [...]

Auhtors: Mengual D, Medrano LE, Villamizar-Villamizar W, Osorio-Llanes E, Mendoza-Torres E, Bolívar S PMID: 35745567 PMCID: PMC9228383 DOI: 10.3390/ph15060648 Abstract Cancer is one of the main causes of death globally. Most of the molecular mechanisms underlying cancer are marked by complex aberrations that activate the critical cell-signaling pathways that play a pivotal role in cell [...]

Auhtors: Tie Y, Tang F, Wei YQ, Wei XW PMID: 35585567 PMCID: PMC9118588 DOI: 10.1186/s13045-022-01282-8 Abstract Immunotherapies like the adoptive transfer of gene-engineered T cells and immune checkpoint inhibitors are novel therapeutic modalities for advanced cancers. However, some patients are refractory or resistant to these therapies, and the mechanisms underlying tumor immune resistance have not [...]