Auhtors: Wimalawansa SJ Abstract Globally, the prevalence of vitamin D deficiency is high, and the incidence is rising. This common micronutrient disorder is easily reversible; so, as the associated morbidity and mortality among affected people. The incidences of vitamin D deficiency continue to increase and have become a pandemic, mostly because of insufficient exposure to [...]

Auhtors: Lin M, Heizati M, Wang L, Nurula M, Yang Z, Wang Z, et al. PMID: 33682538 DOI: 10.1080/08037051.2021.1880881 Abstract Purpose: Hypertension commonly co-exists with diabetes mellitus (DM), and both are closely related to adverse health outcomes. The activation of aldosterone and mineralocorticoid receptor (MR) may play important roles in this process. Therefore, we aim [...]

Auhtors: Aydin M, Kose E, Odabas I, Meric BB, Demirci D, Aydin Z PMID: 33773535 PMCID: PMC8286684 DOI: 10.31557/APJCP.2021.22.3.725 Abstract Introduction: The aim of this study is to determine the effects of aerobic and stretching exercises on quality of life and depression levels of breast cancer patients. Methods: A total of 48 women (mean age [...]

Auhtors: Fong D, Christensen CT, Chan MM PMID: 33563159 DOI: 10.2174/1574892816666210208232251 Abstract Background: Cancer is a multistep process involving genetic and epigenetic changes in the somatic genome. Genetic mutations as well as environmental factors lead to the initiation, promotion, and progression of cancer. Metastasis allows cancer cells to spread via circulatory and lymphatic systems; secondary [...]

Auhtors: Nasrollahzadeh A, Momeny M, Fasehee H, Yaghmaie M, Bashash D, Hassani S, et al. PMID: 34182011 DOI: 10.1016/j.bbamcr.2021.119087 Abstract Due to its potent anti-tumor activity, well-investigated pharmacokinetic properties and safety profile, disulfiram (DSF) has emerged as a promising candidate for drug repurposing in cancer therapy. Although several molecular mechanisms have been proposed for its [...]

Auhtors: Das M, Ellies LG, Kumar D, Sauceda C, Oberg A, Gross E, et al. PMID: 33495474 PMCID: PMC7835248 DOI: 10.1038/s41467-020-20743-7 Abstract Accumulating evidence indicates that obesity with its associated metabolic dysregulation, including hyperinsulinemia and aberrant circadian rhythms, increases the risk for a variety of cancers including postmenopausal breast cancer. Caloric restriction can ameliorate the [...]

Auhtors: Ganeriwal SA, Ryan GA, Purandare NC, Purandare CN doi: https://doi.org/10.1016/j.tjog.2020.11.004 Abstract Cesarean section (CS) is one of the most commonly performed surgical operations in the world and has resulted in improved maternal and neonatal morbidity and mortality rates internationally. However, concerns have been raised regarding the ever increasing CS rates to what has been [...]

Auhtors: Montagnese C, Porciello G, Vitale S, Palumbo E, Crispo A, Grimaldi M, et al. PMID: 33396551 PMCID: PMC7824271 DOI: 10.3390/nu13010136 Abstract Healthy lifestyles are associated with better health-related quality of life (HRQoL), favorable prognosis and lower mortality in breast cancer (BC) survivors. We investigated changes in HRQoL after a 12-month lifestyle modification program in [...]

Auhtors: Pan Y, Yu Y, Wang X, Zhang T PMID: 33365025 PMCID: PMC7751482 DOI: 10.3389/fimmu.2020.583084 Abstract Tumor-associated macrophages (TAMs) represent one of the main tumor-infiltrating immune cell types and are generally categorized into either of two functionally contrasting subtypes, namely classical activated M1 macrophages and alternatively activated M2 macrophages. The former typically exerts anti-tumor functions, [...]

Auhtors: Dach J Abstract After three family members were stricken with aggressive cancer, I realized I had to get up to speed on the jargon of cancer research, and devise my own cancer toolkit of repurposed drugs and supplements if I wanted my loved ones to survive. This book is a record of that journey [...]