Jorge R Miranda-Massari, Alondra P Toro, Doris Loh, Jose R Rodriguez, Raul Morales Borges, Victor Marcial-Vega, Jose Olalde, Miguel J Berdiel, Neil H Riordan, Juan Manuel Martinez, Armando Gil, Michael J Gonzalez PMID: 34947872 PMCID: PMC8708699 DOI: 10.3390/life11121341 AbstractCurrently available anti-viral drugs may be useful in reducing the viral load but are not providing the [...]

Authors: Holford P, Carr AC, Zawari M, Vizcaychipi MP PMID: 34833042 PMCID: PMC8624950 DOI: 10.3390/life11111166 Abstract Severe respiratory infections are characterized by elevated inflammation and generation of reactive oxygen species (ROS) which may lead to a decrease in antioxidants such as vitamin C and a higher requirement for the vitamin. Administration of intravenous vitamin C [...]

Severe respiratory infections are characterized by elevated inflammation and generation of reactive oxygen species (ROS) which may lead to a decrease in antioxidants such as vitamin C and a higher requirement for the vitamin.

Auhtors: Welsh J, Bak MJ, Narvaez CJ PMID: 36028390 PMCID: PMC9509427 DOI: 10.1016/j.molmed.2022.07.002 Abstract Phylloquinone (vitamin K1) and menaquinones (vitamin K2 family) are essential for post-translational γ-carboxylation of a small number of proteins, including clotting factors. These modified proteins have now been implicated in diverse physiological and pathological processes including cancer. Vitamin K intake has [...]

Authors: Tomassa-Irriguible TM, Lielsa-Berrocal L PMID: 34243781 PMCID: PMC8269403 DOI: 10.1186/s12937-021-00727-z Abstract There are limited proven therapeutic options for the prevention and treatment of COVID-19. We underwent an observational study with the aim of measure plasma vitamin C levels in a population of critically ill COVID-19 adult patients who met ARDS criteria according to the [...]

Authors: Zhang J, Rao X, Li Y, Zhu Y, Liu G, Guo G et al. PMID: 34106642 PMCID: PMC8133047 DOI: 10.1097/MD.0000000000025876 Abstract Background: Patients infected with a virus usually lack vitamin C. High-dose vitamin C has an antiviral effect, and has been used by several researchers to treat COVID-19 by intravenous infusion, achieving good results. [...]

INTRODUCTION: Our aim was to investigate the efficacy of vitamin C, melatonin, and zinc in patients with severe Covid-19.

Authors: Patterson G, Isales CM, Fulzele S PMID: 33532123 PMCID: PMC7801272 DOI: 10.14336/AD.2020.0918 Abstract The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been spreading around the world at an exponential pace, leading to millions of individuals developing the associated disease called COVID-19. Due to the novel nature and the lack of immunity within humans, [...]

Authors: Lankadeva YR, Peiris RM, Okazaki N, Birchall IE, Doenom A, Evans RG et al. PMID: 33239507 PMCID: PMC7803449 DOI: 10.1097/CCM.0000000000004770 Abstract Objectives: Oxidative stress appears to initiate organ failure in sepsis, justifying treatment with antioxidants such as vitamin C at megadoses. We have therefore investigated the safety and efficacy of megadose sodium ascorbate in [...]

Authors:Shakoor H, Feehan J, Dhaheri AS, Ali HI, Platat C, Ismail LC. PMID:PMC7415215 DOI: 10.1016/j.maturitas.2020.08.003 Abstract The world is currently in the grips of the coronavirus disease (COVID-19) pandemic, caused by the SARS-CoV-2 virus, which has mutated to allow human-to-human spread. Infection can cause fever, dry cough, fatigue, severe pneumonia, respiratory distress syndrome and in [...]