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  • Published On: October 27, 2021

    Reference: New methods, old brains – A systematic review on the effects of tDCS on cognition of elderly people.

    Authors: Siegert A, Diedrich L, Antal A PMID: 34776903 PMCID: PMC8578968 DOI: 10.3389/fnhum.2021.730134 Abstract The world's population is aging. With this comes an increase in the prevalence of age-associated diseases, which amplifies the need for novel treatments to counteract cognitive decline in the elderly. One of the recently discussed non-pharmacological approaches is transcranial direct current [...]

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  • Published On: October 23, 2021

    Reference: Efficacy of non-invasive brain stimulation on global cognition and neuropsychiatric symptoms in Alzheimer’s disease and mild cognitive impairement: A meta-analysis and systematic review.

    Authors: Teselink J, Bawa KK, Koo GK, Sankhe K, Liu CS, Oh P PMID: 34700007 DOI: 10.1016/j.arr.2021.101499 Abstract Background: Non-invasive brain stimulation (NIBS) techniques have shown some promise in improving cognitive and neuropsychiatric symptoms (NPS) in people with Alzheimer's disease (AD) and its prodromal stage, mild cognitive impairment (MCI). However, data from clinical trials involving [...]

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  • Published On: June 24, 2021

    Reference: Intervention effect of non-invasive brain stimulation on cognitive functions among people with traumatic brain injury: A systematic review and meta-analysis.

    Authors: Ahorsu DK, Adjaottor ES, Lam BY PMID: 34202739 PMCID: PMC8301762 DOI: 10.3390/brainsci11070840 Abstract This systematic review and meta-analysis aggregated and examined the treatment effect of non-invasive brain stimulation (NIBS) (transcranial direct current stimulation and transcranial magnetic stimulation) on cognitive functions in people with traumatic brain injury (TBI). A systematic search was conducted using databases [...]

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  • Published On: April 12, 2021

    Reference: Long-COVID syndrome-associated brain fog and chemofog: Luteolin to the rescue.

    Authors: Theoharides TT, Cholevas C, Polyzoidis K, Poliotis A PMID: 33847020 PMCID: PMC8250989 DOI: 10.1002/biof.1726 Abstract COVID-19 leads to severe respiratory problems, but also to long-COVID syndrome associated primarily with cognitive dysfunction and fatigue. Long-COVID syndrome symptoms, especially brain fog, are similar to those experienced by patients undertaking or following chemotherapy for cancer (chemofog or [...]

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  • Published On: November 9, 2020

    Reference: BR-BCSC Signature: The Cancer Stem Cell Profile Enriched in Brain Metastases that Predicts a Worse Prognosis in Lymph Node-Positive Breast Cancer.

    Auhtors: Dionisio MR, Vieira AF, Carvalho R, Conde I, Oliveira M, Gomes M, et al. PMID: 33182375 PMCID: PMC7695320 DOI: 10.3390/cells9112442 Abstract Brain metastases remain an unmet clinical need in breast oncology, being frequently found in HER2-overexpressing and triple-negative carcinomas. These tumors were reported to be highly cancer stem-like cell-enriched, suggesting that brain metastases probably [...]

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  • Published On: September 1, 2020

    Reference: Association of central noninvasive brain stimulation interventions with efficacy and safety in tinnitus management. A meta-analysis.

    Authors: Chen JJ, Zeng BS, Wu CN, Stubbs B, Carvalho AF, Su KP PMID: 32644131 PMCID: PMC7349076 DOI: 10.1001/jamaoto.2020.1497 Abstract Importance: Tinnitus has a prevalence of 10% to 25% and is frequently associated with numerous complications, such as neuropsychiatric disease. Traditional treatments have failed to meet the needs of patients with tinnitus. Noninvasive brain stimulation [...]

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  • Published On: April 8, 2020

    Reference: Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice.

    Authors: Xu TT, Li H, Dai Z, Lau GK, Li BY, Zhu WL et al. PMID: 32268299 PMCID: PMC7185103 DOI: 10.18632/aging.103035 Abstract The natural polyamine spermidine and spermine have been reported to ameliorate aging and aging-induced dementia. However, the mechanism is still confused. An aging model, the senescence accelerated mouse-8 (SAMP8), was used in this [...]

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  • Published On: February 6, 2019

    Reference: Non-invasive brain stimulation for the rehabilitation of children and adolescents with neurodevelopmental disorders: A systematic review.

    Authors: Finisguerra A, Borgatti R, Urgesi C PMID: 30787895 PMCID: PMC6373438 DOI: 10.3389/fpsyg.2019.00135 Abstract In the last years, there has been a growing interest in the application of different non-invasive brain stimulation techniques to induce neuroplasticity and to modulate cognition and behavior in adults. Very recently, different attempts have been made to induce functional plastic [...]

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  • Published On: November 27, 2018

    Reference: Residual vision activation and the brain-eye-vascular triad: Dysregulation, plasticity and restoration in low vision and blindness – a review.

    Authors: Sabel BA, Flammer J, Merabet LB PMID: 30412515 PMCID: PMC6294586 DOI: 10.3233/RNN-180880 Abstract Vision loss due to ocular diseases such as glaucoma, optic neuropathy, macular degeneration, or diabetic retinopathy, are generally considered an exclusive affair of the retina and/or optic nerve. However, the brain, through multiple indirect influences, has also a major impact on [...]

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  • Published On: October 11, 2018

    Reference: Noninvasive brain stimulation in psychiatric disorders: a primer.

    Authors: Brononi AR, Sampaio-Junior B, Moffa AH, Aparicio L, Gordon P, Klein I et al. PMID: 30328957 PMCID: PMC6781710 DOI: 10.1590/1516-4446-2017-0018 Abstract Objective: Noninvasive brain stimulation (NIBS) techniques, such as transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS), are increasingly being used to treat mental disorders, particularly major depression. The aim of [...]

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