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  • Published On: March 4, 2022

    Reference: Comparison of Moderna versus Pfizer-BioNTech COVID-19 vaccine outcomes: A target trial emulation study in the U.S. Veterans Affairs healthcare system.

    Authors: Ioannou GN, Locke E, Green PK, Berry K DOI: https://doi.org/10.1016/j.eclinm.2022.101326 Abstract Background mRNA COVID-19 vaccines manufactured by Pfizer-BioNTech (BNT162b2) and Moderna (mRNA-1273) have been shown to be efficacious but have not been compared in head-to-head clinical trials. Methods We designed this observational study to emulate a target trial of COVID-19 vaccination by BNT162b2 versus [...]

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  • Published On: March 1, 2022

    Reference: Peripheral neuropathy evaluations of patients with prolonged long COVID.

    Authors: Oaklander AL, Mills AJ, Kelley M, Toran MK PMID: 35232750 PMCID: PMC8889896 DOI: 10.1212/NXI.0000000000001146 Abstract Background and objectives: Recovery from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection appears exponential, leaving a tail of patients reporting various long COVID symptoms including unexplained fatigue/exertional intolerance and dysautonomic and sensory concerns. Indirect evidence links long COVID [...]

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  • Published On: February 27, 2022

    Post: Is the CDC Hiding COVID Data? Find Out About Hospitalizations & Boosters

    The Centers for Disease Control and Prevention has come under fire for failing to publish large segments of data related to COVID-19.  The data includes statistics on hospitalizations and the efficacy of booster shots.

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  • Published On: February 25, 2022

    Reference: Role of Zinc and Zinc Ionophores in Brain Health and Depression Especially during the COVID-19 Pandemic.

    Authors: Ahmed A, Ghit A, Houjak A, Elkazzaz M DOI: 10.5772/intechopen.102923 Abstract Zinc is a trace metal ion that has a role in both physiological and pathological processes, making it one of the most common and necessary components involved in brain function. Besides, zinc is required for cell proliferation control in a variety of mechanisms, [...]

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  • Published On: February 24, 2022

    Reference: The neuroprotective effects of intermittent fasting on brain aging and neurodegenerative diseases via regulating mitochondrial function.

    Authors: Zhao Y, Jia M, Chen W, Liu Z PMID: 35218914 DOI: 10.1016/j.freeradbiomed.2022.02.021 Abstract Intermittent fasting (IF) has been studied for its effects on lifespan and the prevention or delay of age-related diseases upon the regulation of metabolic pathways. Mitochondria participate in key metabolic pathways and play important roles in maintaining intracellular signaling networks that [...]

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  • Published On: February 22, 2022

    Reference: Alopecia in COVID-19: Systematic review and meta-analysis.

    Authors: Nguyen B, Tosti A PMID: 35224518 PMCID: PMC8860672 DOI: 10.1016/j.jdin.2022.02.006 Abstract Background: COVID-19 is associated with androgenetic alopecia (AGA), telogen effluvium (TE), and alopecia areata (AA). No studies have analyzed the aggregate data to date. Objective: We conducted a systematic review to characterize the types, incidence, timing, and clinical outcomes of COVID-19-associated alopecia. Methods: [...]

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  • Published On: February 1, 2022

    Reference: Zinc as a neuroprotective nutrient for COVID-19-related neuropsychiatric manifestations: A literature review.

    Authors: Cereda G, Ciappolino V, Boscutti A, Cantu F, Enrico P, Oldani L PMID: 34634109 PMCID: PMC8524565 DOI: 10.1093/advances/nmab110 Abstract The outbreak of the pandemic associated with Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) led researchers to find new potential treatments, including nonpharmacological molecules such as zinc (Zn2+). Specifically, the use of Zn2+ as a [...]

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  • Published On: February 1, 2022

    Reference: Targeting the monocytic-endothelial-platelet axis with maraviroc and pravastatin as a therapeutic option to treat long COVID/Post-acute sequelae of COVID (PASC).

    Authors: Patterson B, Yogendra R, Guevara-Coto J, Osgood E, Bream J, Parikh P DOI:10.21203/rs.3.rs-1344323/v1 Abstract Post-acute sequelae of COVID (PASC), or long COVID, is a multisystem complication of SARS-CoV-2 infection that continues to debilitate millions worldwide thus highlighting the public health importance of identifying effective therapeutics to alleviate this illness. The [...]

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  • Published On: January 11, 2022

    Reference: Probiotic improves symptomatic and viral clearance in Covid-19 outpatients: a randomized, quadruple-blinded, placebo-conttrolled trial.

    Authors: Gutierrez-Castrellon P, Gandara-Marti T, Abreu AT, Nieto-Rufino CD, Lopez-Orduna E PMID: 35014600 PMCID: PMC8757475 DOI: 10.1080/19490976.2021.2018899 Abstract Intestinal bacteria may influence lung homeostasis via the gut-lung axis. We conducted a single-center, quadruple-blinded, randomized trial in adult symptomatic Coronavirus Disease 2019 (Covid19) outpatients. Subjects were allocated 1:1 to probiotic formula (strains Lactiplantibacillus plantarum KABP022, KABP023, [...]

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  • Published On: January 10, 2022

    Reference: Use of N-Acetylcysteine at high doses as an oral treatment for patients with COVID-19.

    Authors: Izquierdo JL, Soriano JB, Gonzalez Y, Lumbreras S PMID: 35084258 PMCID: PMC8795755 DOI: 10.1177/00368504221074574 Abstract Infection by SARS-CoV-2 causing coronavirus disease 2019 (COVID-19) can be associated with serious and life-threatening conditions, including acute respiratory distress syndrome (ARDS). Severity and mortality have been related to a cytokine storm, an imbalance of oxidative stress, and a [...]

    read more
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