Auhtors: Yu EW, Gao L, Stastka P, Cheney MC, Soto MT, Ford CB, et al. PMID: 32150549 PMCID: PMC7062239 DOI: 10.1371/journal.pmed.1003051 Abstract Background: There is intense interest about whether modulating gut microbiota can impact systemic metabolism. We investigated the safety of weekly oral fecal microbiota transplantation (FMT) capsules from healthy lean donors and their ability [...]

Auhtors: Vallianou NG, Stratigou T, Tsagarakis S PMID: 30342053 DOI: 10.1016/j.diabres.2018.10.008 Abstract Alterations in the diversity or structure of gut microbiota known as dysbiosis, may affect metabolic activities, resulting in metabolic disorders, such as obesity and diabetes. The development of more sophisticated methods, such as metagenomics sequencing, PCR-denaturing gradient gel electrophoresis, microarrays and fluorescence in [...]

Auhtors: Baracos VE, Martin L, Korc M, Guttridge DC, Fearon KCH PMID: 29345251 DOI: 10.1038/nrdp.2017.105 Abstract Cancer-associated cachexia is a disorder characterized by loss of body weight with specific losses of skeletal muscle and adipose tissue. Cachexia is driven by a variable combination of reduced food intake and metabolic changes, including elevated energy expenditure, excess [...]

Auhtors: Cao Y, Wu K, Mehta R, Drew DA, Song M, Lochhead P, et al. PMID: 28377387 PMCID: PMC5628103 DOI: 10.1136/gutjnl-2016-313413 Abstract Objective: Recent evidence suggests that antibiotic use, which alters the gut microbiome, is associated with an increased risk of colorectal cancer. However, the association between antibiotic use and risk of colorectal adenoma, the [...]

Authors: Klooker TK, Braak B, Koopman KE, Welting O, Wouters MM, Schemann M PMID: 20650926 DOI: 10.1136/gut.2010.213108 Abstract Background: Mast cell activation is thought to be involved in visceral hypersensitivity, one of the main characteristics of the irritable bowel syndrome (IBS). A study was therefore undertaken to investigate the effect of the mast cell stabiliser [...]