Auhtors: Zitvogel L, Galluzzi L, Viaud S, Vétizou M, Daillère R, Merad M, Kroemer G

PMID: 25609166 PMCID: PMC4690201 DOI: 10.1126/scitranslmed.3010473

Abstract

Changes in the interactions among the gut microbiota, intestinal epithelium, and host immune system are associated with many diseases, including cancer. We discuss how environmental factors infuence this cross-talk during oncogenesis and tumor progression and how manipulations of the gut microbiota might improve the clinical activity of anticancer agents.

Keywords: cancer, gut microbiota, intestinal epithelium, immune system

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