Ivermectin Cancer and Statins
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Hello,
My father is about to start taking Ivermectin in addition to his conventional cancer therapies. I checked his current prescriptions to see if there are any possible drug interactions. The one possible interaction I found is with Atorvastatin which he takes 20mg a day.
I found the following information:
Atorvastatin
The risk or severity of rhabdomyolysis can be increased when Ivermectin is combined with Atorvastatin.
Atorvastatin and Ivermectin
Combining ivermectin with atorvastatin can increase the risk or severity of muscle-related side effects, specifically myopathy and rhabdomyolysis. Rhabdomyolysis is a serious condition involving muscle breakdown that can lead to kidney damage. Both drugs independently can cause muscle toxicity, and their combination may heighten this risk, although the overall incidence remains low.
While some drug interaction checkers report no direct interactions, multiple authoritative sources highlight the potential for increased muscle toxicity when these medications are used together. If co-administration is necessary, patients should be monitored for symptoms such as unexplained muscle pain, tenderness, or weakness, and for elevated creatine kinase (CK) levels.
What statins are safe to use with Ivermectin?
All commonly used statins—including atorvastatin, simvastatin, lovastatin, pravastatin, fluvastatin, pitavastatin, and rosuvastatin—have a potential risk of increased muscle toxicity (rhabdomyolysis) when combined with ivermectin. This interaction is not limited to a single statin; the risk is noted across the entire class.
There is no evidence from current drug interaction databases or literature that any specific statin is categorically “safe” to use with ivermectin, as all may carry this risk to varying degrees. If statin therapy is required alongside ivermectin, close monitoring for muscle pain, weakness, or elevated creatine kinase (CK) levels is recommended, regardless of which statin is chosen.
My questions is, is anyone here taking large doses of Ivermectin in addition to a statin? If so, have you had any problems?
I’m assuming we will need to monitor his creatine kinase (CK) levels and vitamin D levels through Quest Diagnostics. If so, how often would you recommend having these specific blood tests done while he’s on this treatment regimen?
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