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powassan virus and IVM?
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powassan virus and IVM?
I live in NH and there have been a couple of powassan virus cases. On in New Hampshire and another in Maine. I did a quick search and see that the powassan virus is a positive sense single stranded rna virus. It’s my understanding that IVM is often beneficial for these types of viruses. The news report in the video below says that there is NO treatment for this virus. Where have I heard that before? A few questions:
1. Is it likely that IVM would help treat this virus?
If so,
2. Despite it being a low risk (very few cases) would it make any sense to take IVM as a prophylatic during tick season? The tick only needs to be attached for 15 minutes to transmit the virus. If it would make sense to take IVM, how frequently? Every week, month?
3. How much would you be willing to bet that the patients were not given IVM? 😀
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3 Replies
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Hi @oakhilltop did you watch the “Beyond Lyme” webinar, they discuss tick born illness prevention and treatment https://imahealth.org/alpha-gal-syndrome-tick-borne-illness/
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Yes I did watch that. It was awhile ago. From what I remember, the discussion was about bacterial infections and also the alpha-gal allergy rise. Powassan is a virus and it seems to me that it is the type of virus that IVM has success with. I’m sure no authority is going to test IVM against the powassan virus. So, I’m wondering what people with more knowledge than I think about treating this virus. It sounds like a very nasty virus if one happens to be unlucky enough to get bitten by an infected tick. And it appears that the people in healthcare don’t know what to do with it.
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IVM is the only known drug that is able to reconstruct nerves see:
https://www.mdpi.com/2227-9059/10/2/335
https://link.springer.com/article/10.15252/emmm.201708743
As the virus attacks the nerves IVM could help in 2 ways.
IVM primarily is a Q-protease inhibitor what means it blocks reassembly of the virus. But all such blockages are not total like a switch on/off as complicated chemical balances are at work and also each cell has multiple enzymes.
I would certainly try it for treatment as it even works for influenza . For prophylaxes its a kind of shooting with canons at mosquitos. For Covid prevention IVM works fine but the chances to get covid are several magnitudes larger than to get the rare tick virus.
So step one is to try whether it works or not as a cure.
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