Nattokinase v. warfarin/coumadin
Tagged: Coumadin interaction, nattokinase, warfarin
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Nattokinase v. warfarin/coumadin
Posted by CP Hutzky0.0205960273743 seconds
on May 10, 2026 at 1:34 pm EDTHi ~
Having Factor V Leiden, I am somewhat relegated to taking warfarin/coumadin to reduce clotting. In my search to find suitable alternatives I came across Nattokinase, as well as other beneficial supplements, I messaged my PHCP to get his take and make sure I did not cause myself additional problems. As you might guess, I was summarily pooh-poohed, with a strong admonishment on the Nattokinase, as it is considered a ‘blood thinner’.
I was wondering if anyone here has looked into or considered Nattokinase [or any other non-pharmaceutical] as an alternative?
TIA…
CPgoldenarrow0.0210750102997 seconds
replied 3 hours, 41 minutes ago 8 Members · 9 Replies -
9 Replies
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My doc (Leading Edge Clinic, Pierre Kory’s group) directed me to start Neprinol AFD, a product made by Arthur Andrew. Neprinol is a mix of enzymes including Nattokinase, serrapeptase, bromelain, etc. It is basically the McCullough protocol for spike removal and could be a good alternative to taking the rat poison. I am taking due to (unvaxed) high spike antibody levels and cholesterol concerns.
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Look into Dr Judy Mikivits on nani. While there look for the product cardio miracle. Its not meant for blood thinning but its supposed to be excellent for the heart.
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I was prescribed low-dose aspirin when I was diagnosed in May 2019 with FMD (fibromuscular dysplasia) in my carotid arteries. After 5 yrs I replaced the aspirin with VenoFlow, a Nattokinase & pycnogenol combo supplement from Lifeextension.com. I take 1 capsule per day. I asked my dr if it was ok to take, and he didn’t know anything about it. I’ve been taking it daily since April 2024 & my annual carotid scans have not changed. Whenever I have blood drawn the tech always comments how well my blood flows. I have never had bleeding or clotting issues. I can’t guarantee it’ll work for your needs, but it may be worth checking out.
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Nattokinase is well known by Big pharma and they did hide it for not damaging their revenue chain… It has two functions: Its a blood thinner and anticoagulant in one. Further it has none of the bad side effect of e.g. Aspirin cardio and all the damage Statine does on you.
See:: https://journals.sagepub.com/doi/10.1177/1177271918785130
Help for Alzheimer :: https://www.myamyloidosisteam.com/resources/can-nattokinase-help-amyloidosis-learn-the-facts
further it can directly reduce the Covid spike :: https://doi.org/10.3390/molecules27175405
Only thing you should know: Take it either on empty stomach with a tiny bit of fruit juice or use acid resistant capsules.
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@4cphut Thanks for asking this here. All of these questions and answers will come up in search and grow over time. Most appreciated.
And for a bit more context for the layman (and @4cphut ) -please correct this excerpt from Perplexity if it needs adjustment.
Factor V Leiden is an inherited clotting tendency, not a disease in the usual sense. It happens because of a gene change that makes factor V harder to switch off, so blood can clot more easily than normal, especially in the legs or lungs.
What it means
- Most people with it never get a clot.
- If a clot does happen, it is usually a deep vein thrombosis in the leg or a pulmonary embolism in the lungs.
- Having one copy of the gene raises risk modestly; having two copies raises risk much more.
Symptoms
Factor V Leiden itself usually causes no symptoms. The first sign may be a blood clot, which can cause leg swelling, pain, warmth, or sudden shortness of breath and chest pain if it reaches the lungs.
Who is at higher risk
Risk goes up with immobility, surgery, long travel, pregnancy, and estrogen-containing medicines such as some birth control pills or hormone therapy. It is more common in people of European ancestry.
Testing and treatment
It is diagnosed with blood testing and sometimes genetic testing. People who have never had a clot usually do not need ongoing blood thinners, while people who have had a clot may need anticoagulant treatment.
Practical advice
If you have Factor V Leiden, it helps to tell doctors before surgery, during hospital stays, or before starting estrogen-based medication. Staying active during travel, keeping hydrated, avoiding smoking, and maintaining a healthy weight can help reduce clot risk.
A simple way to think about it: your blood has a built-in “clot more easily” setting, but that setting only becomes a real problem when other risk factors stack on top of it.
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Japan is the world’s number one consumer and producer of Natto Kinase. Take it myself for cardio support. Age 71
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I have no idea what Factor V Leiden is but with my own problems with clotting might be different than yours. So, I had a vein filter clog up with blood clots and did not realize it. I was walking around with most of my torso vein clogged up as well as starting to go down both legs and my body compensating by creating small capillaries everywhere. Eventually went to the emergency room, admitted to hospital with herparin. Released two days later with prescription for Xarelto 20mg/day. Taking that stuff made me feel like I was going to have a stroke any moment. There was also no guarantee the clots would dissolve anytime soon. So I did my own research and found two “systemic enzymes” that seem to help me. 1. Dr. Wong’s Essentials “Zymessence” obtained through his website, and 2. AST Enzymes “Excellecor” obtained from Amazon. Zymessence is stronger. 6 of his capsules equal about 15 of Excellecor. Both have an enzyme called Serrapeptase + other ingredients. Dr Wong suggested I should take 9 of his/day until I felt better. So I did. 9 months later, the Vascular MD has me get a CT scan and report came back saying previous filter clot not seen. See the MD and when I told her I took the systemic enzymes she scolded me. Then I said I started bleeding, and she proceeded to laugh at me. Then I said I stopped the Xarelto completely (but kept taking the special enzymes) and the bleeding stopped. She made it sound like I would die if I did not choose her way of doing things but I had the choice what to do. So, one year 1-1/2 years later I still take about 6 Zymessence and 6 Excellecor and have started to reduce the dose down to 3 Zymessence and 9 Excellecor and we’ll see what happens. I also take 2 grams of L-Citrulline (1g/meal) to help with vascular health. Have absolutely no idea if this helps your condition, this is just my story and I will continue to take the enzymes as long as I can afford the out-of-pocket expense. Why this is not “standard of care” and paid for by insurance is because the System is a money-making racket not interested in optimizing our HEALTH. Good luck to you.
By the way, Do Wong HATES nattokinase because at high doses it can act just like Xarelto and cause uncontrolled bleeding. In other words, the usual K1 injection to induce clotting in an uncontrolled bleeding situation does not work! Coumadin does not have this problem and is safer, but also harder to dose on a week-by-week basis. Personally, I HATE the American health system for being so corrupt and purposely not studying solutions to problems that they cannot profit from. “Standard of Care” needs to be banned. Just my OPINION, of course, so don’t sue me!
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