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Ivermectin with dangerous ingredient?
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Ivermectin with dangerous ingredient?
Hi
A good friend of mine, a naturopath and ER nurse has recently stopped taking Ivermectin for prevention purposes, saying that almost all Ivermectin now contains an emulsifier called Polysorbate 80. She thinks only those people with Covid or spike can benefit at all, that the detrimental effect of polysorbate outways the benefits. IMO, most ivermectin gels could probably contain Polysorbate. I have capsules and am taking to prevent coming down with a flu. Has anyone heard about the problem with Polysorbate yet? Tks
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11 Replies
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Thanks @eagle_ag Good question. Asked my AI friend Perplexity and this is the answer:
Polysorbate 80 is a common emulsifier used in some ivermectin formulations, particularly topical creams (like 1% ivermectin for rosacea) and certain oral or veterinary solutions, to improve solubility and stability. Not all ivermectin products include it—standard human oral tablets like Stromectol typically do not.
Potential Concerns
Concerns about Polysorbate 80 include increased intestinal permeability, which may disrupt nutrient absorption (e.g., minerals like calcium and potassium) and promote inflammation or bacterial translocation. It has also been linked to hypersensitivity reactions, anaphylactoid events, and gut microbiome disruption in studies, though effects vary by dose and individual sensitivity.
Safety Context
In pharmaceuticals, it’s widely used (e.g., in oncology drugs) but can cause injection-site reactions or oxidative stress in vitro; human risks are debated and often tied to high doses. Check specific product labels, as Polysorbate 80-free ivermectin alternatives exist. Consult a healthcare provider for personalized advice.
Here’s a study – https://pmc.ncbi.nlm.nih.gov/articles/PMC6015121/ Hope this helps
pmc.ncbi.nlm.nih.gov
Safety of Polysorbate 80 in the Oncology Setting - PMC
Polysorbate 80 is a synthetic nonionic surfactant used as an excipient in drug formulation. Various products formulated with polysorbate 80 are used in the oncology setting for chemotherapy, supportive care, or prevention, including docetaxel, ...
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Thanks to you and your AI friend perplexity who certainly delivered a great result. Am grateful u took the time to answer. Just wondering where do I find perplexity?
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https://www.perplexity.ai/ Hey @eagle_ag is one of the AI offerings. We, in the IMA, use it to try find answers to great observations like yours.
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She is only referring to Veterinary products. Most have switched to these industrial type emulisfiers (a yellowish gel). Previously, they were made with GRAS (Generally Recognized As Safe) emulsifiers and looked like a white paste. The only one I know of that still looks like this is Ivercare by Farham. However, all these brands keep it a secret what their Inactive Ingredients list is. She should not stop taking IVM, just get it from a licensed compound pharmacy (I use 3 Rivers Pharmacy but there are others). Does this help?
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Hey thanks a lot goldenarrow. This is very helpful.
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👍
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I don’t think “Petmectin” contains it. It’s not listed on the ingredients.
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I seriously wonder if all manufacturers of IVM are required to list thses kinds of ingredients. Tks for ur answer.
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When I first see concerns such as this, my blood pressure goes up. Then I realize that it shouldn’t be a concern for me since I get my ivermectin in either powdered (in capsules by prescription) or tablet form (India), which would have no need for use of an emulsifier. However, I realize that many folks do not want to, or cannot spend the money for prescription meds, and try to make do with veterinary products designed for pets – which is a lot cheaper, but with more health risks – too bad, since pure ivermectin is a remarkably safe drug.
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@AaronAF There are still many bans in many countries for ‘correct’ ivermectin, so sometimes the only option is veterinary. I did like the instant blood pressure picture, then the relax after.😀
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May I suggest checking with the MSDS if using veterinary form of ivermectin. As an example consider the pour on type for cattle like IVOMEC (a brand name). Before use, you should download the Safety Data Sheet (MSDS) for the product. Pour on generally uses Isopropyl alcohol, IPA, so you will have to test for skin sensitivity as the expected strength is >50<70.. I have not found any additional elements added to the product on the MSDS or box label. In lab tests identified in the MSDS their studies revealed no cariogenic action.
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