Treating Lung Nodules

  • Treating Lung Nodules

    Posted by [email protected] on November 6, 2025 at 8:00 pm EST

    I’ve been a smoker for 45 years I’ve been on the pre lung cancer screening since 2018 at which time I had about 10 nodules that were suspicious. In 2019 one of them seemed to be growing quickly so rather than do a biopsy, because it was hard to get to, they did a segmentectomy and removed the top 1/8 to ¼ top of my left lower lobe to remove the entire nodule. Which after testing turned out to be: Histologic Type: Invasive adenocarcinoma, micropapillary predominant, other subtypes present include acinar (20%). Since then I’ve been getting a CT scan every six months and an occasional PET scan. I have two ground grass nodules that are of particular interest that are growing at a faster rate than the other ones which are mostly solid. Based on the testing of the one that was removed there’s about a 90% certainty that these are of the same genre. The growth rate is very slow they’ve only grown about 1 centimeter in all three dimensions in the last five years.

    The purpose of this post and to start the discussion to find out if there are repurposed drugs that can hinder or stop the growth of these nodules. I have tried various things over the last five years but not intensely and none of it seemed to do make a difference the growth rate seems to be consistent, but slow. My most recent PET scan does show an uptake of glucose but at a very low level the lightest color on the PET scan that you can have.

    All the things that I’ve read about repurposed drugs and the way they work on the pathways they really need an active pathway to do their job. Am I understanding this correctly? I guess my question is that since the activity at such a low level what kind of repurposed drug could work at that level and would I have to take it continuously in order to be always present in the body?

    Thanks for entertaining this discussion.,

    [email protected] replied 3 days, 9 hours ago 6 Members · 11 Replies
  • 11 Replies
  • DBartonRD

    Member
    November 6, 2025 at 10:13 pm EST

    You might want to watch the IMA webinar from last night (11/5/25) on cancer. It was very informative and many resources available on the IMA website were mentioned.

    • IMA-GregT

      Member
      November 7, 2025 at 10:51 am EST

      @DBartonRD Thank you, was a really helpful webinar (as they all are :))

  • CharliePh

    Member
    November 6, 2025 at 10:52 pm EST

    After the webcast of last night, you need to hunt for an integrative oncologist, ideally through this site. Also get a copy of Paul Marik’s Cancer Care second Edition. Focus on the lifestyle tomorrow before you can research an integrative Oncologist…

    That’s what I’d do

    Good luck

    • IMA-GregT

      Member
      November 7, 2025 at 10:49 am EST

      👍@CharliePh h It was another great webinar. Lots of empowering info.

  • Jamey Nichols

    Member
    November 7, 2025 at 6:30 am EST

    Friend, sorry for your health news. Make sure you have plenty of spiritual and emotional support. Makes a world of difference in outlook over outcome.

    You’re searching for a more precise approach and I’d point you and your integrative oncologist towards Astron Health (based in England). They can do genomic testing on your malignant tissue samples and determine a more particular recommendation for metabolic pathways to up or down regulate unique to you. No, you don’t need to travel there. And remember, if there’s no integrative oncologist nearby, you could consult IMA for telehealth referral options. Astron might also have additional names with whom they’re networked. Always worth asking. Finally, type “integrative oncology” into the search field of something like Apple Podcasts and find other integrative oncs who’ve been interview guests. The movement is growing! Many of those might be willing to do telehealth appointments.

    Prayers for you. God bless. (James 5:16)

    • IMA-GregT

      Member
      November 7, 2025 at 10:50 am EST

      @jamey Great reply – thank you.

  • Jeff Gerber

    Member
    November 7, 2025 at 8:04 pm EST

    Have a read through this article: https://link.springer.com/article/10.1007/s10989-019-09895-3

    • IMA-GregT

      Member
      November 8, 2025 at 10:07 am EST

      👍 Thanks @jrgerber

      • [email protected]

        Member
        November 12, 2025 at 3:07 pm EST

        Thanks, I will check it out.

  • IMA-GregT

    Member
    November 8, 2025 at 9:47 am EST

    @rmbuckatt-net from Dr. Paul Marik

    Thank you for your question.. there is no simple answer.

    From what you are describing this is a low grade tumor with low activation of the glycolytic pathways.

    Nevertheless, the fact that it is malignant and the fact that the PET is positive (albeit at a low level) indicates that the cancer is driven by metabolic reprogramming and glycolytic enzyme activation.

    Therefore, anti-Warburg repurposed drugs should slow the growth of the tumor.. see table below and attachment.

    These should be taken for ever. i.e the rest of your life.

    In addition, it is important to follow a low glycemic diet; ideally ketogenic.

    Please keep us updated.

    Paul Marik.

  • [email protected]

    Member
    November 12, 2025 at 3:23 pm EST

    Thanks for your response, Dr. Mark. I will try to stick to the diet not always easy though. I can give status of my compliance and growth rate every 6 months after CT scans, if the post is still around. My biggest problem is candy, chocolate. Thanks again for your answer.

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