How to increase lymphocytes

  • How to increase lymphocytes

    Posted by Cindi Anderson on April 15, 2025 at 12:48 pm EDT

    Any supplements or drugs that are known to increase lymphocytes?

    After radiation therapy for cancer my total lymphocytes dropped in half
    to about 1, and in 3 years I haven’t been able to increase them.

    I take several things that are supposed to increase NK cells, and many things that supposedly “help the immune system:. My B cells are low normal due to an immune deficiency (although my main problem is they make antibodies incorrectly.) If I could get my WBC/lymphocytes to go up, at least I’d have more working immune cells.

    Thanks

    Cindi Anderson replied 19 hours, 51 minutes ago 5 Members · 5 Replies
  • 5 Replies
  • IMA-HelenT

    Organizer
    April 15, 2025 at 2:34 pm EDT

    Hi @qofmiwok thanks for this question.

    I am not a medical doctor, but I often use AI to get my research started, and I thought I would share the AI answer with you:

    Yes, there are several supplements, nutrients, and medications that may help increase lymphocyte levels, depending on the cause of low counts. Lymphocytes (a type of white blood cell) play a vital role in immune function, so increasing them can support immunity when levels are low due to illness, medications, or other factors.

    🧬 Supplements & Nutrients That May Help Increase Lymphocytes

    Zinc

    Crucial for immune cell function, including T-lymphocytes.

    Deficiency is linked to reduced lymphocyte counts.

    Vitamin C

    Enhances immune function and helps protect lymphocytes from oxidative damage.

    Vitamin D

    Plays a regulatory role in immune responses.

    Low levels have been associated with decreased lymphocyte activity.

    Vitamin B6

    Essential for the production and function of white blood cells.

    Folate (Vitamin B9) and Vitamin B12

    Support DNA synthesis and cellular replication, which affects white blood cell production.

    Echinacea

    An herbal supplement believed to enhance immune activity and white blood cell production.

    Astragalus Root

    Traditional Chinese herb known to stimulate the immune system and possibly raise lymphocyte counts.

    Colostrum

    Contains immune-supportive proteins and may help enhance lymphocyte response.

    Reishi Mushroom (Ganoderma lucidum)

    Shown to modulate the immune system and possibly increase lymphocyte activity.

    Hope this helps you explore these as possible solutions.

  • Jeff Gerber

    Member
    April 16, 2025 at 10:55 pm EDT

    https://tuckercarlson.com/tucker-show-patrick-soon Dr. Soon-Shiong had mentioned in this video a couple of things additionally that help NK. IIRC he said sleep and infrared light, but I’d have to watch again to catch all of what he mentioned. I’m a big proponent of IR light benefits and I have a system at home. IR light has an additive effect with methylene blue and that combination is worth researching as well. There have been many experiments over the years that involve both. The 2023 FLCCC talks by Dr. Mobeen Syed (Methylene Blue) and Dr. Paul Marik (Infrared) explains the physics of both (electron transport chain complex IV). Hearing IR reinforced by Dr. Soon caught my attention once again to the amazing range of applications. Skin cancer is another interesting application of combining both that I recently read an article about. Hopefully that gives you some more ammunition to bolster your immune system with!

  • robin-whittle

    Member
    April 17, 2025 at 12:11 am EDT

    It would not be surprising if an unhealthily low number of lymphocytes was at least partly caused by inadequate circulating 25-hydroxyvitamin D.

    The immune system can only function properly with 50 ng/mL (125 nmol/L = 1 part in 20,000,000 by mass) circulating 25-hydroxyvitamin D, as measured in “vitamin D” blood tests. Most people have less than this, especially in winter and if they have black or brown skin, are elderly and/or have sun avoidant lifestyles.

    25-hydroxyvitamin D (calcifediol AKA “calcidiol” is produced, over several days, primarily in the liver by hydroxylating vitamin D3 (cholecalciferol) on the 25th carbon. Neither of these are hormones. These are not signaling molecules. The immune system does not use hormonal signaling.

    There is very little vitamin D in food, including in food fortified with vitamin D3 or the less effective vitamin D2. Until the late 1920s, the primary source of vitamin D3 was ultraviolet-B irradiation of the skin, where it breaks a bond, opening up one of the carbon rings of 7-dehydrocholesterol to form a molecule which changes shape of its own accord to become stable vitamin D3. Far from the equator, sufficient UV-B light to do this is only available in the middle of cloud-free summer days, without glass, clothing or sunscreen intervening. However, this UV-B also damages DNA and so raises the risk of skin cancer.

    In winter, many people who do not supplement vitamin D3 at all, or who do so in the very small amounts recommended by many doctors (such as 25 micrograms = 1000 IU a day, on average) have 25-hydroxyvitamin D levels below 25 ng/mL (62.5 nmol/L). Some have 5 ng/mL (12.5 nmol/L) or less, even in sunny Israel, See Figure 1 in https://www.medrxiv.org/content/10.1101/2020.09.04.20188268v1.

    Consequently, most people cannot be fully healthy without proper vitamin D3 supplementation.

    If we had no supplemental vitamin D3, health would be optimised by some level of UV-B skin exposure which trades off the skin cancer risk against the essential benefits of improving immune system function by raising 25-hydroxyvitamin D levels. However, since vitamin D3 (produced by UV-B irradiation of 7-dehydrocholesterol made from wool fat) is so inexpensive and readily available, the best approach is to supplement properly and avoid excessive UV-B exposure.

    Please see the research articles cited and discussed at: https://vitamindstopscovid.info/00-evi/.

    This includes descriptions of the compounds and recommendations from New Jersey based Professor of Medicine Sunil Wimalawansa on how much vitamin D3 cholecalciferol to supplement, on average, per day, to attain at least 50 ng/mL circulating 25-hydroxyvitamin D after several months, without the need for blood tests or medical monitoring. The amount depends on body weight and obesity status. For 70 kg 154 lb body weight, without obesity, 0.125 mg (125 micrograms = 5000 IU) is a good amount.

    “5000 International Units” a day sounds like a lot, but it is a gram every 22 years. Pharma grade vitamin D3 costs about USD$2.50 a gram ex-factory.

    Most doctors are not aware of the immune system’s need for 50 ng/mL or more circulating 25-hydroxyvitamin D, so they regard 20 ng/mL (50 nmol/L) or perhaps 30 ng/mL (75 nmol/L) as sufficient for good health. These levels are sufficient to supply the kidneys in their role of maintaining a very low (0.05 to 0.1 ng/mL) level of circulating calcitriol (1,25-dihydroxyvitamin D) in the bloodstream, where it functions as a hormone – a long-distance, blood-borne (also perhaps in the cerebrospinal fluid) molecule whose level (concentration) affects the behavior of one of more types of cell in distant parts of the body. This is the one hormonal function of the three molecules – to enable the kidneys to play their role in regulating calcium-phosphate-bone metabolism.

    Most doctors and immunologists are not aware of 25-hydroxyvitamin D ==> calcitriol intracrine (inside an individual cell, sometimes mistakenly referred to as “autocrine”) and paracrine (to nearby cells, often of different types) signaling, since they have only been discovered in the last 20 years and since there are no peer-reviewed tutorials which explain them. These signaling systems are unrelated to hormonal signaling and are essential to many types of immune cell’s ability to respond to their changing circumstances. I wrote a non-peer-reviewed tutorial on these signaling systems in 2020: https://vitamindstopscovid.info/02-intracrine/. A simplified version is at: https://vitamindstopscovid.info/00-evi/#02-compounds.

    • IMA-GregT

      Organizer
      April 18, 2025 at 6:15 am EDT

      👍 Thanks very much robin-whittle. Great info.

  • Cindi Anderson

    Member
    April 18, 2025 at 3:59 pm EDT

    Thanks HelenT and jrGerber, I take all those. Robin-whittle my vit D levels are high.

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