[Stephen White]

Found this online; don’t know if it helps.

https://pmc.ncbi.nlm.nih.gov/articles/PMC10312243/

pmc.ncbi.nlm.nih.gov

Saline nasal irrigation and gargling in COVID-19: a multidisciplinary review of effects on viral load, mucosal dynamics, and patient outcomes - PMC

With unrelenting SARS-CoV-2 variants, additional COVID-19 mitigation strategies are needed. Oral and nasal saline irrigation (SI) is a traditional approach for respiratory infections/diseases. As a multidisciplinary network with expertise/experience ...

[IMA-GregT]

👍 – Thanks swonder

[Patricia A Hurd]

I use Snoot from frontierpharm.com. Feels great and has antibacterial properties! Check it out!

[IMA-GregT]

👍 thanks jehurd

[Shaul Shakked]

I use this and it helps:

https://www.amazon.com/NORTH-AMERICAN-HERB-SPICE-SinuOrega/dp/B0011DTL78?th=1

[Dana Mccarthy]

Xlear commecial product. This can be made diy recipe found online.

[IMA-GregT]

👍

[schreib69]

another vote for Xlear!

It works, easy to use.

Just do it.

[IMA-GregT]

👍

[James Kringlee]

Just before indoor “shared air” exposure I 1st spray home mixed antiviral 12% xylitol in PLAIN sterile filtered water into my nose and mouth to saturation and the need to blow my nose. (a scant tsp xylitol in a 30 mL nasal pump type fine metered spray bottle such as “Snoot” brand) I use birch xylitol. Cleans nose – improves biome – reduces viral binding – antiviral activity. Plain water, not saline, seems best here per published research and confirmed in a Steve Kirsch interview with the head of Xlear, a company that produces and sells products with xylitol.

Then a few sprays of home mixed antiviral 0.5% povidone-iodine in sterile saline breathed deep as sprayed into each nostril and mouth and from a bit of a distance (aiming between the eyes at bridge of nose) a couple of sprays on to open eyes and eye area. (1 part povidone-iodine solution 10% to 19 parts saline solution note: some prefer a 1% mix 1 part povidone-iodine to 9 parts saline) Kills the damn virus. I choose more sprays, 4 into each nostril and into mouth of 0.5% (perhaps I will go to 0.6% as 1 study found more effective than 0.5%) for perhaps better wetting and coverage vs fewer sprays, ie. 2 sprays of 1%. I ignore trials started 5 days after testing positive, perhaps 10 days after infection that show no benefit. Probably offers good protection up to 3 hours. 1 study showed viral killing was gone at 4 hours. I found one hospital system mixing it, 0.5%, fresh every day out of concern that in solutions less than 1% the iodine, over time, may be released from the povidone bond. I understand this would make the iodine stronger and more irritating as free iodine dissolved out of the povidone. note: in Japan a 0.23% formulation is marketed. They were using it in the hospital 5 times over the course of the work day from just before starting work to just after finishing work. I give it a good shake before use, I mix a little at a time and use it up, if I had older solution and found it irritating I would mix up a new bottle. I have found the 0.5% very easy to use.

I started out from Dr George Domb, ENT https://krcrtv.com/news/local/<wbr>redding-doctor-says-he-may-<wbr>have-a-solution-to-prevent-<wbr>transmission-of-covid-19 if it does not stay visible, refresh and rapidly click on the page as it momentarily appears. He used 1/2 tsp povidone-iodine solution 10% in a 44mL squeeze bottle of saline nasal spray. His cautions for its use (for prevention) “Do not use it if you are pregnant, breastfeeding, have hyperthyroidism, are being treated for thyroid cancer with irradiated iodine, or hypersensitive to iodine. It should not be used on children younger than 6.” I, personally, would certainly use it for all at the first sign of possible covid infection.

I wipe the spray nozzle and inside of the nozzle cap with a piece of tissue damped with a bit of bleach and clean out the spray bottle and sprayer using 70% isopropyl alcohol , spraying with the cap on loosely to rinse it out and shake out the bottle and spray out the sprayer then air dry before refilling. Xylitol in plain water will support mold growth spots inside the bottle. Before refilling I put a bit of bleach solution in the bottle put the sprayer back on the bottle, shake, spray let it sit a bit then rinse with sterile water

After the xylitol and PVI sprays I put on a 3M N95 and add the side shields to my normal looking safety eye glasses – any eyeglasses help. Comfortable breathable 3M “Aura” 9205+ N95 with weak straps that break or the Aura 9210+ with probably stronger straps, both which fits the most people and which have a filtration efficiency of, see test # 644, . Keeping out 99.68% – “total leakage” through and around the mask – of salt test particles with a median size the size of a smaller single sars-cov-2 virus and within the salt test particle mix particles 30 times smaller and twice as large approximating the size of a larger single sars-cov-2 per wickedpedia sars-cov-2 size data . see Aaron Collins testing masks on youtube. Also see there how easy it actually is to adjust N95 masks for fit. I also use the 8210+ with a filtration efficiency of 99.80% see test # 636 because it is so easy to put on and take off fast and wear for a few minute “encounter” for protection from the curb side pickup “close talker” or cough or sneeze in the face. Aaron Collins has said the 3M™ VFlex™ Particulate Respirators 9100 Series was his “new favorite” because it is exceptionally breathable. It is also the lowest cost and available in 2 sizes. Mask test data available here https://docs.google.com/<wbr>spreadsheets/d/<wbr>1M0mdNLpTWEGcluK6hh5LjjcFixwmO<wbr>G853Ff45d3O-L0/edit?pli=1#gid=<wbr>1976839763 note: the electrostatic charge fills all the space between the fiber of the masks so that very tiny particles with little mass are easily captured by the electrostatic charge which draws the fine particles to the fibers and sticks them there. These may also be quite effective against tiny toxic “shed” particles. note: the 95% rating is against a larger, heavier, “most penetrating” size and mass particle.

After indoor “shared air” exposure, when back home, depending on perceived risk from infected shared air exposure, I use 1% Johnson’s regular “no more tears” baby shampoo in sterile saline for nasal flush using a NeilMed 8 ounce nasal flush bottle, for eye wash from palm of clean hand or eye wash cup – blinking a lot and for mouthwash/gargle. (1 tsp/5mL baby shampoo per ~16 ounces/500 mL saline) then, as you will, a few sprays of PVI. The baby shampoo in saline is a viral killer and good cleaner. I may also nebulize a few mL (8 ml?) of regular vodka – easy to do after a few partial “diluted” 1/2 breaths. I use the Philips respironics “InnoSpire Elegance”, no prescription needed from some on line suppliers, low cost 100% duty cycle . I think this would be better, easier to breathe, if enough “saline mix” was added to the vodka to convert the 60% water fraction in the vodka to normal saline. note: A anti-covid ethanol nebulization study states that nebulization creates such tiny particles that the ethanol and water separate by rapid evaporation into very high percent ethanol and water. note: I think that if the right amount of baking soda / salt saline mix was added to dissolve in the water component of vodka, in addition to outright killing of the virus some additional inhibition of viral cell entry and inhibition of viral replication in the cell could be possible. note: Nebulation is a key to therapeutic delivery of covid-19 prevention and treatment including, per Dr Zelenko and David Scheim PhD, hydroxychloroquine where as few as 1 or 2 pills worth of HCQ nebulized almost immediately builds the therapeutic effect, and more, of a full course of pills without potential systemic side effects or contraindications.

For saline I use 1 part baking soda 3 parts salt which is close to the NeilMed formula for saline mix.

(by measuring a couple of NeilMed saline mix packs) to make 2 cups/16 ounces/500mL 1/4 tsp baking soda 3/4 tsp salt. I boil the water from a 500 mL bottle of filtered water for a few minutes, let it cool down then add the baking soda and salt. I let it cool till just warm because heat chemically changes baking soda.

IMO Very much worth the effort for the high risk. Actually simple after a routine has been established. Most all may actually be at risk over the long term from some “spike” pathology even from “mild” covid and also from the spike “vaccine” antigen.

ps. the 2 times per day nasal flush study that reduced hospitalization of covid sick older high risk people by 8 times added either 1/2 tsp of povidone-iodine solution 10% OR 1/2 tsp of baking soda to 1 cup/8 fluid ounces of “normal” (NeilMed) saline. Both the povidone-iodine and the alkalizing baking soda mix worked ~ equally well.

continued below as a reply to this comment

[James Kringlee]

Addition to my comment on BASIC PREVENTION

Keys are 1) Keep it out – Avoidance, N95 and eye protection 2) Kill it before and if it gets in – povidone-iodine, ethanol, and soap/detergent/baby shampoo, isopropyl alcohol 3) Stop entry into the cell – Add raise PH over 6.8 baking soda, and any number of other options to stop entry into the cell 4) Stop replication in the cell if it gets in – Add hypertonic saline, probably simply ~2 times “normal” concentration, and any number of other options to stop replication in the cell

I first used home mixed antiviral azelastine eye drops and recently the 0.5% povidone-iodine / saline spray for eyes. Which is better? I do not know. Azelastine was shown early on to be an effective sars-cov-2 antiviral at the prescribed concentration (which prescribed concentration was not referenced). The prescribed concentration for eye drops is 0.05%. The new over the counter “Astepro Allergy” azelastine nasal spray is 0.15% azelastine, even stronger than the prescription version azelastine nasal spray. (good for your covid kit) At walmart I bought Astepro and a 0.5 FL OZ (15 mL) “Sterile Artificial Tears” which I used, I also bought the Equate 0.5 FL OZ (15 mL) “Dry Eye Relief” (or your choice or sterile saline?) Wash first and sterilize hands with 70% isopropyl alcohol and all – syringe,tsp measure if used, dish to put bottle tops on. I first shook the bottles a bit and let them sit to settle. I wiggled off the top of the eye drop bottle gripping it with a piece of paper towel wet with 70% isopropyl alcohol. I poured out and discared 1 tsp / 5 mL. I unscrewed the Astepro top, put it on the plate and poured to fill the 1 tsp / 5 mL.measuring spoon and used a sterilized syringe (it was not marked with graduations) to put this into the eye drop bottle. There has been no visible (clear bottle) change in this mixed, now antiviral eye drop solution for over a year.

note: A study shows adding such as ~1% Johnson’s regular baby shampoo (1 tsp/5ml per 500 mL) to 70% isopropyl alcohol improves its efficacy as a hand sanitizer. The 70% version evaporates slower SO it has more viral killing “dwell time” on hands. Probably the better (vs 91%) choice for budget hand sanitizer application. I have found no drawbacks to adding 1% Johnson’s baby shampoo to 70% isopropyl alcohol for home mixed hand sanitizer.

Review of the use of nasal and oral antiseptics during a global pandemic https://www.ncbi.nlm.nih.gov/<wbr>pmc/articles/PMC7842245/

When considering a combination of both baking soda and salt – for some applications some combination which both raises PH above 6.8 around the cell area it contacts and has a saline concentration of around 1.5% or so is indicated in Light of some of the references below.

Hypertonic saline solution inhibits SARS-CoV-2 in vitro assay https://www.biorxiv.org/<wbr>content/10.1101/2020.08.04.<wbr>235549v2 “Our data shows that 260 mM NaCl (1.5%) inhibits 100% SARS-CoV-2 replication in Vero cells. Furthermore, our results suggest that the virus replication inhibition is due to an intracellular mechanism and not due to the dissociation between spike SARS-CoV-2 protein and its human receptor angiotensin-converting enzyme 2 interaction. NaCl depolarizes the plasma membrane supposedly associated with the inhibition of the SARS-CoV-2 life cycle. This observation could lead to simple, safe and low cost interventions at various stages of COVID-19 treatment, improving the prognosis of infected patients, thereby mitigating the social and economic costs of the pandemic.” my note: saline does not block viral entry via ACE2.

my note: when the cell is “flooded” with hypertonic saline this causes the cell to redirect cell energy the virus is using for replication to use that cell energy to re-balance the sodium concentration in the cell thereby stopping viral replication use of that cell energy as this “re-balance” process proceeds.

SARS-CoV-2 requires acidic pH to infect cells https://pubmed.ncbi.nlm.nih.<wbr>gov/36048924/ “we show that fusion and genome penetration require virion exposure to an acidic milieu of pH 6.2 to 6.8, …. . We define a key role of an acidic environment for successful infection, found in endosomal compartments and at the surface of TMPRSS2-expressing cells in the acidic milieu of the nasal cavity.” “pH catheter placed in the left and right nasal cavities of 17 healthy male and female volunteers, we found a mildly acidic pH of around 6.6”

Lowering the transmission and spread of human coronavirus https://onlinelibrary.wiley.<wbr>com/doi/10.1002/jmv.26514 ” A 1% baby shampoo nasal rinse solution inactivated HCoV greater than 99.9% with a 2-min contact time.”

I also ignore (EXCEPT FOR A BIT OF TRUTH NOTED BELOW) such as this typical mis dis mal information “study” from bioweapon baric and the bioweapon baric gain of function gang and colleagues at the university of north carolina at chapel hill et al. “Pharmacokinetic‐based failure of a detergent virucidal for severe acute respiratory syndrome–coronavirus‐2 (SARS‐CoV‐2) nasal infections: A preclinical study and randomized controlled trial” https://www.ncbi.nlm.nih.gov/<wbr>pmc/articles/PMC9011886/ ( SOUNDS REAL “OFFICIAL”) They started the trial much much too late to show benefit and they only tested for viral load reduction in nasal cells just inside the opening of the nostrils. The only area tested was “(about 2cm) or until you feel resistance”. into the nose “with self‐administered mid‐turbinate swabs”

“The primary outcome measure in the clinical trial was change in SARS‐CoV‐2 viral load over 21 days” The earliest swabbing was 3 to 4 days after they tested positive so perhaps 10 days after infection – so way too late. People collected and then stored the swabs at home for weeks.before sending them in. Wonder of wonder no difference between the control and “experimental” groups.

BIT OF TRUTH from the “study” note: J&J = Johnson & Johnson regular baby shampoo “(Figure 2A,B). Having identified a nontoxic concentration of J&J/S (½ tsp J&J/240 ml saline), we then showed that this concentration of J&J/S exhibited robust virucidal activity against SARS‐CoV‐2 at varying titers (Figure 2C). Further assays of virucidal activity demonstrated that this concentration was also virucidal in vitro against NL63 coronavirus and respiratory syncytial virus (Supplementary Figure 2A,B).

note: they used 2 packets of NeiMed saline mix in 240mL of water to make a hypertonic saline – 1 packet in 240mL / 8 fluid ounces / 1 cup makes normal saline.

As we know “they” also did this type study to discredit all Real early treatment, Real ER treatment, Real in hospital treatment and most everything actually useful to stop hospitalization and death including a povidone-iodine is bad (overdosed) “study” that only showed using much more povidone-iodine than needed caused a temporary, quickly reversed, elevation of thyroid markers. There was even an obvious “set-up” “povidone-iodine is bad ” website to push that “study”.. All adding evidence in the Provable – Depraved-heart mass murder of millions. see Depraved-heart murder definition at wickedpedia here https://en.wikipedia.org/wiki/<wbr>Depraved-heart_murder

ncbi.nlm.nih.gov

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[IMA-GregT]

👍 Thanks jamesk.

[jwilliamearnhardt]

https://articles.mercola.com/sites/articles/archive/2023/01/08/how-to-nebulize-hydrogen-peroxide.aspx

100% effective, systemically effective, inexpensive.

Also see Dr. Tom Levy, MD, JD article on same.

jwemd

articles.mercola.com

Can Nebulized Peroxide Help Against Respiratory Infections?

Dr. David Brownstein explains how nebulized peroxide may help fight respiratory infections.

[IMA-GregT]

👍 thanks jwemd.

[dickatlee]

FWIW, for several years, in the evening after being in an enclosed public space, I use peroxide:
Nasal: NeilMed bottle with 4oz saline (3 NeilMed pkts/gallon distilled water) + 3.0 ml H2O2 (my max to avoid discomfort)
Deep gargle (tongue up to get to back of throat): 10ml H202 in 4oz tap water = 4 gargles

I admit to being a bit concerned about the impact of H2O2 on mucosal tissue, but haven’t seen any serious objections to it.

[theornerynurse]

I swear by Xlear twice a day and Listerine mouthwash/gargle for my own personal use (not medical advice).

[Jenrae68]

I use NaturaNectar Nasal Spray with propolis. They also have other powerful propolis supplements.

I also use Sovereign Silver colloidal silver nose spray. Hope this helps.

https://pmc.ncbi.nlm.nih.gov/articles/PMC8391193/#:~:text=As%20an%20antiviral%20agent%2C%20propolis,syndrome%20coronavirus%202%20(SARS%2DCoV

pmc.ncbi.nlm.nih.gov

Anti-Viral and Immunomodulatory Properties of Propolis: Chemical Diversity, Pharmacological Properties, Preclinical and Clinical Applications, and In Silico Potential against SARS-CoV-2 - PMC

Propolis, a resin produced by honeybees, has long been used as a dietary supplement and folk remedy, and more recent preclinical investigations have demonstrated a large spectrum of potential therapeutic bioactivities, including antioxidant, ...

[donmidwest]

I purchased Xlear brand Xylitol based nasal spray based on a strong recommendation by Peter McCollough two years ago. I cannot find that video but here is a link to his opinions.

“<b style=”background-color: var(–bb-content-background-color);”>Xylitol Nasal Spray Prevents SARS-CoV-2 Infection<b style=”background-color: var(–bb-content-background-color);”>Results from a Prospective Randomized, Double-Blind, Placebo-Controlled Trial

Peter A. McCullough, MD, MPH

Feb 22, 2023″

https://petermcculloughmd.substack.com/p/xylitol-nasal-spray-prevents-sars

I purchased 2 bottles and used them but don’t know if they worked for me. I am going on a trip next month and I am going to get another bottle to take on the flight.

I tried to delete the photo of Peter below that came up automatically after I posted the link. If anyone can delete that it is OK with me.

A 1:30 long testimonial from a mom is posted on Amazon in which her family extols the benefits of Xlear spray for allergies.

https://www.amazon.com/live/video/0febbdcdfb734cf3b713a676bcaa9d5d?

substack.com

Peter A. McCullough, MD, MPH | Substack

Internist, cardiologist, and epidemiologist: Co-author (with John Leake) of "The Courage to Face COVID-19: Preventing Hospitalization & Death While Battling the Bio-Pharmaceutical Complex."

[grantmorgan1906]

I have thyroid issues and can’t use iodine. I use peroxide and squeeze bottle saline nasal spray. I spray both nostrils with saline spray and then dip a qtip (both ends) into the peroxide. Swab both nostrils twice and blow out. I do it morning and night daily.

[Guido Socher]

Somebody mentioned already Snoot but just make your own Chlorine Dioxide (ClO2) nasal spray for pennies. It’s amazing. My wife had a bad cold (we think it was covid) a few weeks ago and I used the homemade ClO2 nasal spray. I did not get sick at all. It’s very gentile. I use 5+5 drops of “MMS” in 30ml of sterile water with a bit of salt.

[dickatlee]

MMS: where do you get it or how do you make it? And what does “5+5” mean in this case?

[Guido Socher]

You can buy this in many places. Amazon is one option. Pierre Kory is currently writing a number of articles about Chlorine Dioxide at https://pierrekorymedicalmusings.com/ . Dr Robert Yoho has a lot of articles at https://robertyoho.substack.com/ (has also detail on where to buy it).
There is the “Curious Substack” https://curioushumanproductions.substack.com/ .
A good place to start is https://theuniversalantidote.com/

5+5 means you mix 5 drop of NaClO2 solution with 5 drops of an activator acid and this produces the ClO2 (Chlorine Dioxide, it’s actually a gas but it dissolves easily in water).